Teat-end mean vacuum is directly related to teat health and milking process (liner adhesion on teat, proper flow rate). Moreover, vacuum fluctuations (cyclic and irregular) increase the risk of bacterial transmission from one teat to the other. Goat sector is yet missing references on factors linked with milking machine and animal, which influence teat-end vacuum. A laboratory experimentation was performed using a milking simulation device, used for International Committee for Animal Recording (ICAR) tests. The influence of six different parameters on vacuum levels in cluster was studied: pipeline height, working vacuum, pulsation type, pulsation rate and ratio and flow rate. The data analysis was based on vacuum stability calculation: vacuum loss and cyclic vacuum fluctuations.In high line, due to a complex milk flow in long milk tube, teat-end vacuum fluctuations are about 4kPa higher than in low line. An increase of flow rate also leads to higher vacuum fluctuations. This relation seems to be linear; however, this hypothesis should be confirmed through another specific experiment. Contrary to other publications, in low line, vacuum fluctuations are slightly intensified by alternate pulsation, compared to simultaneous one (+1.3kPa). A farm experiment should be carried out, in order to check these results with real field situation and to analyze the effects of these vacuum fluctuations levels on milking incident frequency and udder health. Vacuum loss analysis reveals that high working vacuum level, especially when associated with low flow rates, may lead to teat-end average vacuum over 38kPa. This point out the interest of reducing overmilking and measuring teat-end vacuum during milking, to help farmers define their proper working vacuum level, with regards to mammary health.