Two-year Comparison Research Articles

Assessing progenies of potato for resistance to skin spot (Polyscytalum pustulans) in the glasshouse

Crosses were made between six parents differing in susceptibility to skin spot and glasshouse-grown tubers from true seedlings of the nine resulting progenies assessed for resistance to the disease. The assessment was evaluated by a two-year comparison with the behaviour of field-grown tubers of the progenies and their parents. The correlations between progenies in the glasshouse and field were r=0.911 and 0.753 and those between the mid-parental values and the progeny means were high (r>0.864), indicating that parental differences were heritable. It is concluded that correlations were sufficient for glasshouse-grown tubers to be used for assessing large numbers of progenies in genetical studies and for eliminating highly susceptible progenies at an early stage in a breeding programme.

2.P.15 Two-year comparison of safety and efficacy of atorvastatin and lovastatin

2.P.15 Two-year comparison of safety and efficacy of atorvastatin and lovastatin

A two-year comparison between the French and Canadian superconducting gravimeter data

SUMMARY This study is devoted to a preliminary comparison of the gravity records provided by two geographically well-separated superconducting gravimeters over a common two-year observing period. The data sets are processed for the first time following exactly the same numerical steps. After a brief description of the observed gravity and pressure signals, we perform a classical least-squares fit to tides, taking into account a single coefficient for the effect of the local barometric pressure fluctuations and a second-order polynomial approximation for the instrumental drift. The results show a totally different drift behaviour between the two instruments. The time fluctuation of the resulting residual gravity signals is shown, as well as the corresponding power spectral density. In particular, we provide detailed statistics on the spectral content of the residual gravity signals. In a subsequent step, we first high-pass filter the observed gravity and pressure signals and then apply an automatic method to detect and remove obvious spikes. A new least-squares fit then provides new residual gravity signals, the power spectral density of which is reduced in all frequency bands, especially in the subtidal band. We finally provide cross-spectral estimates of these two residual gravity sets indicating a further reduction in the power spectral density level.

Immune Status of Asymptomatic HIV-Infected Hemophiliacs: Randomized, Prospective, Two-Year Comparison of Treatment with a High-Purity or an Intermediate-Purity Factor VIII Concentrate

It has been postulated that high-purity factor VIII (FVIII) concentrates, since they contain less alloantigenic proteins than intermediate-purity concentrates, might cause lesser deterioration of the immune systems of hemophilic patients infected with the human immunodeficiency virus (HIV). To evaluate this hypothesis, we have prospectively compared T-lymphocytes subsets and delayed hypersensitivity reactions to skin tests in 17 asymptomatic HIV-positive hemophiliacs randomly assigned to continue treatment with an intermediate-purity concentrate with those of 16 hemophiliacs changed to a high-purity concentrate. For both groups, during the 24-month follow-up period CD4 cell counts showed similar rates of fall from baseline values. There was also no difference in the number of patients anergic to skin tests. Three patients treated with the intermediate purity concentrate and one treated with the high-purity concentrate developed symptoms of HIV infection. On the whole, no striking benefit is conferred to the immune status of asymptomatic HIV-positive hemophiliacs by using this high-purity concentrate for 2 years.

The impact of a very high purity factor VIII concentrate on the immune system of human immunodeficiency virus-infected hemophiliacs: a randomized, prospective, two-year comparison with an intermediate purity concentrate [see comments

Pathophysiologic considerations as well as non-comparative clinical results suggest that very high purity concentrates may slow immunologic deterioration in human immunodeficiency virus (HIV)-infected hemophiliacs. In an attempt to evaluate this hypothesis, we prospectively compared CD4 cell counts, skin testing responses, and changes of the clinical status in 20 asymptomatic HIV-positive hemophiliacs, randomly assigned to continue the treatment with an intermediate purity concentrate or to receive a very high purity product, purified by immunoaffinity chromatography with monoclonal antibodies. In the group switched to the very high purity concentrate there was no significant change of the CD4 cell counts over the 96-week follow-up period, whereas in the group continued on the intermediate purity concentrate, a highly significant decline was detected (P less than .013). Furthermore, in the very high purity group, four of six anergic patients at entry acquired reactivity to skin testing. The results of this study clearly support the use of very high purity concentrates for the replacement therapy of HIV-infected hemophiliacs.

A Two-Year Comparison Dental Study of 132 Naval Reserve Recruits

A Two-Year Comparison Dental Study of 132 Naval Reserve Recruits

A two-year comparison of three topical fluoride agents

AVERILL, H. M.; AVERILL, JEANNE E.; RITZ, ANGELINE G.; LITTLE, MARGARET F. Author Information