The transmission end of large-scale wind power generation bases faces challenges such as high AC-DC coupling strength, low system inertia, and weak voltage support capabilities. Deploying distributed synchronous condensers (SCs) within and around wind farms can effectively provide transient reactive power support, enhance grid system inertia at the transmission end, and improve dynamic frequency support capabilities. However, the high investment and maintenance costs of SCs hinder their large-scale deployment, necessitating the investigation of optimal SC configuration strategies at critical nodes in the transmission grid. Initially, a node inertia model was developed to identify weaknesses in dynamic frequency support, and a critical inertia constraint based on node frequency stability was proposed. Subsequently, a multi-timescale reactive power response model was formulated to quantify the impact on short-circuit ratio improvement and transient overvoltage suppression. Finally, a two-stage optimal configuration strategy for distributed SCs at the transmission end was proposed, considering dynamic frequency support and transient voltage stability. In the first stage, the optimal SC configuration aimed to maximize system inertia improvement per unit investment to meet dynamic frequency support requirements. In the second stage, the configuration results from the first stage were adjusted by incorporating constraints for enhancing the multiple renewable short-circuit ratio (MRSCR) and suppressing transient overvoltage. The proposed model was validated using the feeder grid of a large energy base in western China. The results demonstrate that the optimal configuration scheme effectively suppressed transient overvoltage at the generator end and significantly enhanced the system’s dynamic frequency support strength.