This study employs the Homotopy perturbation method to analyze the behavior of immiscible, incompressible fluids within a cylindrical coaxial tube, focusing on scenarios relevant to physiological fluid dynamics, particularly in the catheterized oesophagus and similar biological systems. Adopting long-wavelength and low Reynolds number approximations, a two-layered model is proposed with a micropolar fluid in the core and a Newtonian fluid in periphery regions. Parameters such as velocity, flux, friction, pressure, and impedance variations are formulated, particularly under the influence of dilating wave amplitude. Generally, when a catheter is introduced, pressure rises. It is further found that while pressure falls with increasing micropolar parameter, it rises with coupling number upon catheter insertion. Thus feeding patients with micropolar fluids during catheter-assisted pre-diagnosis is impractical due to associated pressure rise. Observations suggest a complex pressure profile during bolus passage through the oesophagus due to the broadening of the catheter size. Additionally, impedance exponentially increases with catheter size, influenced by the micropolar parameters and the coupling numbers, with micropolar fluids exhibiting higher impedance than that with Newtonian fluids. However, this study underscores the significant impact of catheterization on physiological fluid dynamics, notably increasing oesophageal impedance by two to threefold. This highlights the critical role of catheters in altering flow characteristics, emphasizing the need for a careful medical intervention during pre-diagnostic assessments.