We use direct numerical simulation (DNS) to explore the effect of tilt on two-dimensional turbulent thermal convection on a half-soap bubble that is heated at its equator. In the DNS, the bubble is tilted by an angle δ∈[0°,90°], the Rayleigh number is varied between Ra∈[3×106,3×109], and the Prandlt number is fixed at Pr = 7. The DNS reveals two qualitatively different flow regimes: the dynamic plume regime (DPR) and the stable plume regime (SPR). In the DPR, small dynamic plumes constantly emerge from random locations on the equator and dissipate on the bubble. In the SPR, the flow is dominated by a single large and stable plume rising from the lower edge of the bubble. The scaling behavior of the Nusselt number Nu and Reynolds number Re is different in these two regimes, with Nu∝Ra0.3 for the DPR and Nu∝Ra0.24 for the SPR. Concerning Re, the scaling in the DPR lies between Re∝Ra0.48 and Re∝Ra0.53 depending on Ra and δ, while in the SPR, the scaling lies between Re∝Ra0.44 and Re∝Ra0.45 depending on δ. The turbulent thermal and kinetic energy dissipation rates (εT′ and εu′, respectively) are also very different in the DPR and SPR. The probability density functions (PDF) of the normalized log εT′ and log εu′ are close to a Gaussian PDF for small fluctuations but deviate considerably from a Gaussian at large fluctuations in the DPR. In the SPR, the PDFs of normalized log εT′ and log εu′ deviate considerably from a Gaussian PDF even for small values. The globally averaged thermal energy dissipation rate due to the mean temperature field was shown to exhibit the scaling ⟨ε⟨T⟩⟩B∝Ra−0.23 in the DPR and ⟨ε⟨T⟩⟩B∝Ra−0.28 in the SPR. The globally averaged kinetic energy dissipation rate due to the mean velocity field is shown to exhibit the scaling ⟨ε⟨u⟩⟩B∝Ra−0.47 in the DPR (the exponent reduces from 0.47 to 0.43 as δ is increased up to 30°). In the SPR, the behavior changes considerably to ⟨ε⟨u⟩⟩B∝Ra−0.27. For the turbulent dissipation rates, the results indicate the scaling ⟨εT′⟩B∝Ra−0.18 and ⟨εu′⟩B∝Ra−0.29 in the DPR. However, the dependencies of ⟨εT′⟩B and ⟨εu′⟩B on Ra cannot be described by power-laws in the SPR.