The primary thesis of this paper is that the character of sedimentary rocks within or directly on top of an ophiolite complex can be used to constrain tectonic models of oceanic crustal genesis. Late Jurassic ( c. 169-161 Ma) Coast Range ophiolite remnants are exposed E and W of the San Andreas Fault in central California. Ophiolite volcanic rocks are mainly sub-alkaline tholeiitic basalts, but include subordinate intermediate and silicic flows and breccias. Available ‘immobile’ major and trace element data indicate that the Coast Range ophiolite formed above a subduction zone, possibly in a fore-arc setting, as suggested by the presence of high magnesian andesites and boninites. The ophiolite extrusives mainly comprise pillow lava and lava breccia formed on a rugged fault-controlled ocean floor. Interlava pelagic sediment is restricted to very small amounts of interstitial red chert and nannoplankton limestone. Widespread occurrence of vesicular lavas probably reflects high primary volatile contents rather than eruption in shallow water. Local interbeds of arc-derived silicic tephra in the uppermost extrusives suggest that the ophiolite and cover sediments formed together in a single tectonic setting. Depositionally overlying deep-water successions up to 600 m thick comprise radiolarian-rich tuffaceous and volcaniclastic sediments of ?Callovian-mid-Tithonian age (165-148 Ma). Depositional processes included airfall, turbidity currents, mass flow and current reworking. Small SiFeMn lenses along the lava-sediment contact formed by hydrothermal replacement of basal siliceous tuffaceous sediments or by direct chemical precipitation. At one locality (Llanada), the ophiolite is overlain by up to 1.8 km of younger (?Tithonian) basic-intermed, and acid lava flows, submarine lahars and mainly silicic pyroclastic sediments, of inferred volcanic arc origin. The volcaniclastic cover passes conformably upwards into late Tithonian and younger terrigenous deep-water clastic sediments of the Great Valley Group, deposited in a fore-arc setting. The Coast Range ophiolite and its cover are interpreted as an incipient intraoceanic volcanic arc, possibly developed above an eastward (continent-ward)-dipping subduction zone within the equatorial Pacific Ocean. In this scenario, short-lived (5–8 Ma) supra-subduction zone spreading to form the ophiolite was followed by ?Callovian-Tithonian arc volcanism, shedding tuffaceous debris onto the adjacent fore-arc. Subduction was active separately along the western American continental margin with the result that the Coast Range arc-ophiolite complex eventually collided with North America, triggering the Late Jurassic Nevadan orogeny and initiating Franciscan subduction-accretion. The Coast Range ophiolite remnants, at least those west of the San Andreas Fault, were apparently translated northwards to their present positions after Late Cretaceous.