Tubular Spaces Research Articles

Fluid transport and tubular intercellular spaces in reptilian kidneys.

Renal tubules of crocodiles, lizards, snakes, and turtles have intercellular spaces similar in type to those observed in the mammalian gall bladder, but different from those of mammalian renal tubules. The fluid movements across renal tubules of reptiles are correlated with the width of the tubular intercellular spaces. In the proximal tubules, where transport is always isosmotic, the spaces are open whenever the tubular epithelium is tranporting, but closed when no transport is taking place. In distal tubules, intercellular spaces are wide open when the osmolality of the urine is close to that of the blood, that is, when the fluid resorbed is almost isosmotic to the tubular fluid. The apical two-thirds of the intercellular spaces are closed when the urine is hypoosmotic. They are also closed when the tubules are not transporting, as in collapsed tubules or tubules poisoned with ouabain. Thus, as in the gall bladder, the open intercellular spaces appear to be found whenever there is fluid transport across the epithelium.

Eruptive Hidradenoma and Syringoma

Eruptive hidradenoma, a rare of syringoma, was studied histologically, histochemically, and electron microscopically in two patients. In spite of its peculiar clinical differences, such as occurrence of numerous lesions with limited distribution to anterior surfaces of the body, it showed features identical to the eyelid syringoma. Direct connections were found between the lesions and epidermis and between individual lesions, but not between the lesions and underlying eccrine secretory segments. Also, cystic or tubular spaces were lined with an immature eccrine intra-epidermal type of epithelium which possessed a periluminal tonofilament band, lysosomes, keratohyaline granules, and often underwent complete keratinization. No secretory epithelium was found in the lesion. Dermal histiocytes with typical Langerhans cell granules and collagen fiber bundles were seen in parenchyma. It seemed that the lesion was undergoing constant destruction and regeneration.

Excretion in fresh-water turtle (Pseudemys scripta) and desert tortoise (Gopherus agassi)

Excretion in fresh-water turtle (<i>Pseudemys scripta</i>) and desert tortoise (<i>Gopherus agassi</i>)