For the intelligent and therefore successful treatment of any surgical ailment an exact knowledge of its pathology and mode of invading the various structures of the body is most important. In the case of tuberculosis of the male genitalia such exact knowledge is in some respects lacking; especially in regard to the structures primarily attacked by this disease. At the present writing, the majority opinion holds that the first structure to become involved in the tuberculous process is the epididymis, and that from this the disease quickly spreads to involve the vesicle and prostate. A smaller number of investigators feel that the disease begins its genital invasion in the prostate, spreading from there to the vesicles and epididymis. This is a question which has long been argued, and is of much more than mere academic importance, because only by eradicating the primary focus may we expect the greatest number of