Troubleshooting Of Problems Research Articles

The Evolution of LC Troubleshooting: Strategies for Improving Peak Tailing

As chromatography technologies change, our approaches to using them in ways that value reliability, as well as the ways we should approach troubleshooting and fixing problems, should also change. In this installment, we continue the discussion started earlier this year about how some specific troubleshooting topics have evolved over time, this time focusing on chemical causes of peak tailing, and strategies that we can use to overcome them. Understanding how knowledge and technologies related to peak tailing have evolved is helpful for troubleshooting problems with peak shape, designing reliability into new methods, and when considering updates to legacy methods that have been in use for decades.

The Evolution of LC Troubleshooting: Degassing

As chromatography technologies change, our approaches to using them in ways that value reliability, as well as the ways we should approach troubleshooting and fixing problems, should also change. In this installment, I continue the discussion started last month about how some specific troubleshooting topics have evolved over time, this time focusing on mobile phase degassing. Understanding how approaches to degassing have evolved is helpful for troubleshooting problems with pumps and detection, designing reliability into new methods, and when considering updates to legacy methods that have been in use for decades.

The Evolution of LC Troubleshooting: Protective Devices and Column Repair

As chromatography technologies change, our approaches to using them in ways that value reliability, as well as the ways we should approach troubleshooting and fixing problems, should also change. In this installment, we survey several protective and troubleshooting strategies, and discuss which approaches have changed over time, and which ones have not. Understanding how the use of these approaches has evolved is helpful both for designing reliability into new methods and when considering updates to legacy methods that have been in use for decades.

Pediatric Hearing Aid Management: Experiences and Perspectives of Spanish-Speaking Parents.

The purpose of the study was twofold: (a) to explore hearing aid management experiences of Spanish-speaking parents who have young children using hearing aids and (b) to explore parents' access to the Internet and perceptions about remote audiology services. The study used a mixed methods design. Data were collected through a phone interview. Eleven mothers of children aged 14-60 months participated. Most of the children (9/11) had a bilateral hearing loss, and two had an additional disability. Three themes emerged for hearing aid management experiences: audiology services, routines, and emotional challenges/supports. Parents had variable levels of confidence in their skills ranging from no confidence to complete confidence, with the greatest variability for three items: (a) using the listening tube to make sure that the sound quality of the hearing aid is good, (b) removing moisture from the earmold tubing, and (c) troubleshooting problems when your child's hearing aids are not working. All participants reported having consistent Internet access and had positive perceptions about the possibility of remote audiology services. This study provided insights into hearing aid management experiences and perceptions of Spanish-speaking parents. Parents described variability for audiology services, routines for hearing aid use and care, and access to other parents of children with hearing loss. Spanish-speaking parents present additional elements in the hearing care process that need to be incorporated in planning. Remote services may be an opportunity to enhance access to support that could improve effectiveness of hearing aid management.

School Nurses' Comfort With Diabetes Management and Technology From 2012 to 2019.

School nurses are integral to optimizing diabetes management for students with type 1 diabetes. The aim of this study was to describe the use of diabetes technology in schools over time and assess school nurses' comfort level performing diabetes management tasks. From 2012 to 2019, school nurses who attended a diabetes education program completed a survey about their experience and comfort level with diabetes management. A total of 1,796 school nurses completed the survey; 56% had at least 5 years of school nursing experience. Most (86%) had at least one student with type 1 diabetes. Among school nurses with at least one student with type 1 diabetes, 73% had at least one student using insulin pump therapy, and 48% had at least one student using continuous glucose monitoring (CGM). There was no change in pump use over time, but the percentage of nurses who had a student using CGM increased significantly from 24% in 2012 to 86% in 2019 (P <0.001). School nurses' comfort level using pumps remained stable over time. Overall, 47% reported being mostly/very comfortable giving boluses using a pump, and 17% reported being mostly/very comfortable troubleshooting problems with a pump. However, there was a significant increase in school nurses reporting feeling mostly/very comfortable working with CGM devices, increasing from 9% in 2012 to 44% in 2019 (P <0.001). School nurses are an important part of diabetes management for school-aged youth with type 1 diabetes. There is a need for additional diabetes education and support to build their confidence with diabetes management and technology, especially with further technological advancements in management.

ML-Based Traffic Classification in an SDN-Enabled Cloud Environment

Traffic classification plays an essential role in network security and management; therefore, studying traffic in emerging technologies can be useful in many ways. It can lead to troubleshooting problems, prioritizing specific traffic to provide better performance, detecting anomalies at an early stage, etc. In this work, we aim to propose an efficient machine learning method for traffic classification in an SDN/cloud platform. Traffic classification in SDN allows the management of flows by taking the application’s requirements into consideration, which leads to improved QoS. After our tests were implemented in a cloud/SDN environment, the method that we proposed showed that the supervised algorithms used (Naive Bayes, SVM (SMO), Random Forest, C4.5 (J48)) gave promising results of up to 97% when using the studied features and over 95% when using the generated features.

Control infrastructure monitoring system at the NSRL facility cluster

The National Synchrotron Radiation Laboratory (NSRL) facility cluster is a collection of user facilities developed by NSRL, including the Hefei Light Source-II (HLS-II), Tunable Infrared Laser for Fundamental of Energy Chemistry (FELiChEM), and THz near-field high-flux material physical property test system (NFTHZ). User facilities generally have high operational availability requirements. The NSRL facility cluster relies on the control infrastructure to provide computing, network, and storage resources, as well as various services that must be available 24 hours a day, 7 days a week. The monitoring system is responsible for tracking the operational status of the control infrastructure, gathering information on faults, performance degradation and cybersecurity issues, and distributing alarm messages in time. It facilitates the operator troubleshooting problems efficiently to improve the availability of the user facilities. The monitoring system is developed by integrating several free and open source software tools. Zabbix is selected as the monitoring tool and collects metrics data from the control infrastructure. Three upper-layer applications are developed for data visualization. The dashboard shows the operational status of the network and various devices. The alarm system collects and distributes alarm messages via web-based GUI and WeChat. The reporting system periodically generates metrics and alarm reports. The monitoring system has been deployed since March 2022. The results indicate that the monitoring system can effectively identify hidden hazards in the control infrastructure.

Sistem Scada Level Air Dalam Tangki Menggunakan PLC dan Sensor MPM4700 Intelligent Level Transmitter

Controlling the water level in the tank will not be a problem if it is only used for household needs. For example, if the water in the tank reaches the low level limit, you can still wait for the pump to work to be used. In contrast to the needs of water used in industry. For example, the use of water in a tank to supply water to a boiler, or a tank used in a mineral water company and others of the same type can be fatal. The use of HMI in a well-designed process industry can support high performance in an industry to produce a system that is easy to understand visually and also makes it easier for operators to handle troubleshooting problems. The availability of analog input output facilities on the PLC can read the output voltage of the water level sensor module. and display on the HMI diagram in real time

Development of Web-Enabled Online Learning Effectiveness Model Based on Online Video Tutorial

Information technology has a major impact on knowledge-sharing activities. The combination of knowledge-sharing tools such as Web 2.0 and multimedia embodied in the use of tutorial videos on web-enabled online learning is the solution. The solution is expected to improve individual performance in solving troubleshooting problems. The model was developed which explained the relationship between knowledge sharing and individual performance in troubleshooting problems and identified the factors that influence it. The research data is obtained by distributing questionnaires online to Telkomsel service users who have experienced problems troubleshooting products or services. The conceptual model was tested based on 205 samples obtained online. From the test results, it can be seen that web-enabled online learning is effective because tacit knowledge sharing that occurs directly increases individual performance while the effect of explicit knowledge sharing is mediated by tacit knowledge sharing. The factors that drive knowledge-sharing activities can influence individual performance, namely trust, IT usage, and usability.

Electronic resource management in a post-Plan S world

cOAlition S and research funding policies mean open access content is no longer a ‘trend’ but rather another consideration of content management for librarians and libraries. In 2018, the authors of this article launched a new version of TERMS (Techniques for Electronic Resources Management). TERMS 2.0 envisages a post-Plan S e-resources life cycle blending e-resources and open access content management. This article outlines how open content management can dovetail into current e-resource management tactics across six TERMS: Investigation of material, procurement and licensing of content, implementation, troubleshooting of problems, evaluation and preservation, and sustainability concerns. Lastly, we reflect on the themes growing in libraries in regard to management of online resources.

The impact of inducing troubleshooting strategies via visual aids on performance in a computerized digital network task

SummaryTroubleshooting is a particular problem‐solving process comprising error detection, fault diagnosis, and system restoration. Since automation of systems has become increasingly complex and ubiquitous, troubleshooting skills are crucial to maintain safety and security in a variety of contexts. The planned study aims at examining troubleshooting strategies and how to induce them by means of simple visual aids and concise instructions. To this end, a computerized task consisting of network troubleshooting problems will be employed in an experimental study with repeated measures. Indicators of strategy use and performance will be tested for their relation to availability and differential use of visual aids, to cognitive styles that affect how individuals deal with challenges or system information, and to cognitive processes that are involved in metacognition and executive function. The planned research is expected to help gain insights into the cognitive determinants of troubleshooting, reverse engineering, and their links to computational thinking.

A not so worthless attempt to develop primary culture from breast FNAC/CNB samples!

Breast cancer is the second leading death-causing cancer in women. Since a longtime, continuous breast cancer cell lines have been used for drug discovery based research. However, these cell lines may not represent the characteristics of original as they are believed to undergo changes due to repeated passaging. Primary cultures directly obtained from the tumor are gaining more attention worldwide as these are believed to mimic the disease process more accurately than that of continuous cell lines. The major problem with the usage of primary culture is to get the sufficient number of cells for the experiments. Here, in this study we attempted to develop primary culture both from FNAC and core needle biopsy (CNB) samples of the breast cancer patients. Overall, we believe that it is not so difficult to establish primary cultures of breast cancer cells from clinical FNAC/CNB samples. However, the starting population in FNAC samples is less which can be a hindrance in getting an adequate number of cells to reach a monolayer. CNB samples may be better quantitatively and stepwise troubleshooting of problems faced can help in the successful establishment of monolayer and primary cultures that can be propagated. We believe, our experience might be helpful for those who are struggling with the development of the short-term primary culture of breast cancer from the small-sized tissue samples.

A Comprehensive Review on Pharmaceutical Film Coating: Past, Present, and Future.

Pharmaceutical film coating is considered a key part in the production of solid pharmaceutical dosage forms since it gives superior organoleptic properties products. In addition, it can improve the physical and chemical stability of dosage forms, and modify the release characteristics of the drug. Several troubleshooting problems such as twinning mottling, chipping, etc., may arise during or after or even during the shelf life of the film coated dosage forms. These troubleshooting problems may be due to tablet core faults, coating formulation faults and/or coating process faults. These problems must be overcome to avoid unnecessary product problems. Film coating as well as other parts of the pharmaceutical technology is subjecting to continuous innovation. The innovation may be at different levels including pharmaceutical excipients, processes, software, guidelines and equipment. In fact, of particular note is the growing interest in process analytical technology, quality by design, continuous coating processing and the inclusion of new ready for use coating formulations. In this review, we tried to explore and discuss the status of pharmaceutical film coating, the challenges that face this manufacturing process and the latest technological advances in this important manufacturing process.

Preparing for a Pandemic: Our Plans and Lessons Learnt as a Department in a Tertiary Care Hospital.

This is a descriptive article aiming to present and analyse the steps of preparedness and troubleshooting of problems faced at operating rooms and intensive care unit during the ongoing coronavirus infectious disease 2019 (COVID-19) pandemic in Our Lady of Lourdes Hospital, a tertiary care hospital in Ireland from February 2020 to March 2020. Concerningpreparation, we reviewed all aspects of our clinical and potential logistic issues and their accessible solutions in times of limited resources. Analysing availability of critical care staff and essential escalation of care area capacity during the ongoing pandemic, we observed that there was strong communication, commitment and team work among departmental and other non-critical care staff, and disciplines. Being the only regional teaching hospital with critical care unit in county Louth, we found ourselves confident and content with our preparation. We found good communication and training as critical factors in the preparation for a pandemic. Key Words: COVID-19, Pandemic, Preparation, Challenges.

Review on Common Observed HPLC Troubleshooting Problems

HPLC provide much higher resolution, more accurate quantitative results, as well as shorter analysis times in comparison to the earlier techniques, HPLC has evolved into an indispensable tool in many analytical laboratories. Troubleshooting is a form of problem solving, often applied to repair failed products or processes. Actually, HPLC refers to a number of separation techniques that use a liquid mobile phase, or eluent. Troubleshooting HPLC instrumentation and separations require a fundamental understanding of how the instrument functions and how the separation works. Common HPLC problems are caused by component malfunctions (pump, degasser, injector, detector, data system, column), and faulty preparation of the mobile phase or sample preparation. Always use well cleaned glassware for preparation for better results. Main key to resolve HPLC problem is Cleaning of HPLC with appropriate solvent. If any problem occurs, it is advisable to perform a quick visual check of the instrument and column. If Monograph or any protocol is provided then try to follow same process. Troubleshooting is a form of problem solving, often applied to repair failed products or processes. Otherwise, we suggest that you read the entire article so as to pick up some ideas that will help you avoid problems in the future. We hope that this article useful to diagnose problems and to gain understanding of underlying causes so that you can prevent or minimize future occurrence. Colum and HPLC care is most important part of troubleshooting. In This article, we tried to cover all major troubleshooting problems.

Optimizing knowledge and skills through protocol-based ECMO management and simulation-based training: A novice clinician's perspectives of a successful ECMO program

Background: Starting a new extracorporeal membrane oxygenation (ECMO) program requires synergizing different organizational aspects and extensive training of a core team to deliver care safely.1,2 Sidra Medicine, a newly opened facility in Qatar, started accepting acute inpatients and activated its ECMO program in 2018. The aim of this quality review is to evaluate the training of ECMO Specialists through benchmarking our ECMO program mechanical complications to the Extracorporeal Life Support Organization (ELSO) data. Methods: The hospital trained ECMO Specialists (experts and novices) come from different parts of the world with varying degrees of knowledge and experience and use a comprehensive training program based on the ELSO guidelines for ECMO training and continuous education.3 This program was delivered over a two-year period to all ECMO team members and included: multiple conferences on key ECMO topics; basic wet labs and emergency drills including the change of different components, and; immersive simulation-based training (SBT) on a modified neonatal manikin (Figures 1 and 2). These face to face interactions, in small groups, with different critical scenarios were followed by debriefing.4,5 SBT sessions started before the opening of the acute unit and continued after the acceptance of the first ECMO patient. Immersive SBT sessions occur monthly and include minor and major troubleshooting, de-airing, priming, circuit change, oxygen failure, pump failure, and other problems that can be encountered during ECMO runs.All ECMO Specialists, both experts and novices, completed a full ECMO training program and had gone through the Sidra ECMO certification examination before handling ECMO patients. They were evaluated and certified using a checklist assessment tool and with skills having to be demonstrated competently by the candidates. Novice clinicians were initially ECMO bedside nurses and as they became familiar with the ECMO daily routine and learned the protocols and policies, they started caring for patients as ECMO Specialists.We retrospectively reviewed collected data of technical complications for the 13 patients who have received ECMO therapy since program activation. We analyzed ECMO mechanical complications and benchmarked them with ELSO registry data in corresponding categories to evaluate the training of ECMO specialists and our ECMO program infrastructure. Result: The Sidra ECMO program has now trained a total of 20 ECMO Specialists (experts and novices). Out of the 13 novice clinicians who volunteered to be trained, 8 successfully became ECMO Specialists.There has been a total of 13 patients on ECMO (Table 1). One of these was the first successful neonatal respiratory ECMO patient in Qatar. Over the 13 cases, minor mechanical complications and usual circuit clots were experienced. There was no pump failure or oxygenator failure encountered. Conclusion: SBT is a valuable ECMO educational approach. It offers the opportunity to practice technical skills repeatedly and to become proficient in high-risk/low frequency events while avoiding harm to patients. Using consistent and continuous training is the key for the success of the ECMO Specialist's model. This is a limited study due to the low number of patients, but as ECMO is a low-volume/high-risk procedure, it still highlights the benefits of simulation in establishing new ECMO programs.

Fungal and marine shell fouling in desalination plant equipment

Abstract The Saudi Arabian Saline Water Conversion Corporation (SWCC) aims to maintain an uninterrupted desalinated water output and has tasked its Desalination Technologies Research Institute (DTRI) with trouble-shooting operational problems and unusual events faced by its desalination plants. Three events were reported and investigated by DTRI. Two were found to involve fungal fouling, and one was found to involve fouling by marine shells. One case of fungal fouling involved a new seawater reverse osmosis membrane and the plant was advised to review the handling and storage practice of membranes. The other case involved product water hoses and manifested itself in the form of black slimy deposits arising from dense fungal growth. The fungus originated from new product hoses and was eliminated by shock-dosing replacement hoses with chlorine. The marine shell fouling involved a feed water line of a combined power/desalination plant. Chlorine, hydrochloric acid, ethylenediaminetetraacetic acid, and fresh water were used to assess their ability to control marine shell fouling in laboratory experiments, with varying results. Since high doses of chlorine were not effective in controlling marine shell fouling, the practice of continuous chlorination should be abandoned in favor of an alternative chlorination regimen, e.g., pulse chlorination.

IGEM Toronto: Promoting Independent Undergraduate Research in Synthetic Biology at the University of Toronto

Finding suitable research opportunities can be stressful for undergraduate students. These experiences can ultimately define a student’s future career path, decision to attend professional school or graduate programs, or interest in work-ing in a specific industrial stream. With academic and job-related applications, including scholarships and funding opportunities, putting greater emphasis on research experience, students are finding themselves seeking any opportu-nities made available to them. This can include becoming a volunteer tasked with basic lab tasks (cleaning, making simple solutions, restocking materials, etc.), or administrative duties (stock inventory, ordering reagents, file organiza-tion), which although important, do not fully allow them to gain the all the skillsets needed to become a researcher. There are also opportunities for students to take on research projects, but often with the project outline and instruc-tions established and given by an upperclassman or principal investigators (PIs), restricting the student from making big decisions or pursuing independent research. Despite being valuable experience, important skills such as designing or planning an experiment, or troubleshooting problems, remain underdeveloped. This creates a large gap in research ability between finishing undergraduate education and entering graduate school or pursuing a research career. So what opportunities are provided for undergraduate students to be independent researchers?

DEVELOPMENT OF THE INFORMATION SEARCH-SYSTEM ”PALEXP” FOR IDENTIFICATION OF PLANT ORIGIN OBJECTS FOR CRIMINALISTIC RESEARCH

One of the most important areas of study of the state institution ”Scientific and Practical Centre of The State Forensic Expertise Committee of The Republic of Belarus” (hereinafter referred to as “the Centre”) is plant objects research using sporo-pollen analysis. Sporo-pollen analysis is used in solving of trouble-shooting problems connected with identifying the territory by the character of flora while determining the time of a crime. The Center for the first time in the Belarusian expert practice conducts research on pollen and spores of plants for the purpose of attributing to one batch of psychoactive substances impregnated with inactive matrix of vegetable origin. In this article, we propose a variant of optimizing palynological expert studies which consists in creating reference information retrieval system ”PalExp” (hereinafter referred to as “RIRS”) in which all information about pollen contains. The architecture and the main components of such a system, the questions of creating categories of accounting in the context of peculiarities of pallinological expert research and related problems of the formalization of information presentation, the basic requirements for the formation and functioning of the RIRS are presented. Advantages of this system as compared to the traditional sources of dendrochronological information are presented. The execution of forensic-palynological expertise with RIRS has a number of advantages, namely: shortening the investigation time, obtaining weighty evidences, as well as providing additional guarantees against unreasonable bringing of citizens to criminal and administrative responsibility. Key words: identification of objects, vegetable objects, forensic investigations, information search system ”PALEXP”.

Can Pair Learning Improve Students’ Troubleshooting Performance in Robotics Education?

In Robotics Education (RE), the hands-on experience with troubleshooting problems is seen as a good catalyst to enhance the participants’ problem-solving skills. Based on the pedagogical technique of collaborative learning and pair programming, pair learning is an emerging and potential method in RE, which means that students collaborate in pairs to construct, build, and program a robot under scripted but switchable roles. As a special collaborative learning, can pair learning also improve students’ troubleshooting performance in RE? Therefore, we conducted a comparison experiment (pair learning versus individual learning) in two classes at a Robot Summer Camp for high school students. The results indicated that (a) in the process of learning making robot artifacts, students in pair learning group (PLG) had a higher success rate in troubleshooting than that of individual learning group (ILG), but failed in other indicators and (b) in the summative test, the troubleshooting performance of students in PLG was similar with that of ILG. The findings showed that, in terms of troubleshooting, collaborative (pair) learning does not always has the superiority over individual learning in RE, which implicates other factors to be explored in future research. Implications for teaching are also discussed in this exploratory study.