A 55-year-old male was admitted to our hospital with severe heart failure. He was diagnosed with triple valve regurgitation and an aneurysm of patent ductus arteriosus (PDA). Infectious etiology was suspected because of the valve morphology, but the patient had no sign of infection. After confirming the complete control of infection, a hybrid operation was planned. The opening of PDA at the pulmonary artery side was closed with a patch, accompanied by a multiple valve surgery, after which the aorta side entry of the aneurism was covered with a stent graft. The patient was treated successfully without complications.