In this paper, the confinement loss of octagonal photonic crystal fibers (PCFs) with an isosceles triangle lattice of air-holes are numerically investigated. Taking into account the confinement loss, the mode field diameter (MFD), the effective area (A eff ) and the chromatic dispersion of octagonal PCFs are calculated, compared to conventional hexagonal PCFs. It is found from confinement loss and MFD results that the octagonal PCFs can confine the field strongly than the hexagonal PCFs due to the different air filling fraction. Moreover, it is shown that the octagonal PCFs are obtained not only positive but also negative larger dispersion values and smaller A eff values compared to the hexagonal PCFs.