Triblock Copolymer Research Articles

Self-Assembly of a Triblock Copolymer in the Presence of a Rigid Conjugated Polyelectrolyte

Self-Assembly of a Triblock Copolymer in the Presence of a Rigid Conjugated Polyelectrolyte

Improving Crystallization Properties, Thermal Stability, and Mechanical Properties of Poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) Bioplastic by Incorporating Cerium Lactate

The more flexible and faster biodegradation rate of poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) (PLLA-PEG-PLLA) triblock copolymer makes it a promising bioplastic compared to PLLA. However, finding effective additives for this triblock copolymer remains a research challenge for their wider applications. This work involved the melt-blending of a cerium lactate (Ce-LA) antibacterial agent with a triblock copolymer. The thermal properties, crystalline structures, mechanical properties, and phase morphology of the PLLA-PEG-PLLA/Ce-LA composites were examined. With 0.5 wt% Ce-LA, the composite exhibited the best crystallization properties. The crystallinity of the composite contained 0.5 wt% Ce-LA increased from 11.8 to 15.9%, and the half-time of crystallization decreased from 3.37 to 1.28 min at 120 °C, compared with the pure triblock copolymer. The incorporation of Ce-LA did not result in any changes to the crystalline structure of the triblock copolymer matrix. The best improvement in thermal stability and tensile properties of the composites was achieved with the addition of 1.5 wt% Ce-LA. When compared to the pure triblock copolymer, the temperature at maximum decomposition rate of PLLA blocks shifted from 310 °C to 327 °C, the tensile strength increased from 14.3 MPa to 19.5 MPa, and the Young’s modulus increased from 204 MPa to 312 MPa. This study concludes that the incorporation of Ce-LA enhanced the crystallizability, thermal stability, and mechanical properties of PLLA-PEG-PLLA, indicating that Ce-LA could serve as a versatile additive to the PLLA-PEG-PLLA bioplastic.

Exploiting Seeded RAFT Polymerization for the Preparation of Graft Copolymer Nanoparticles.

Although seeded reversible addition-fragmentation chain transfer (RAFT) polymerization is explored as a unique method for the preparation of block copolymer nanoparticles with diverse structures, the preparation of nonlinear polymer nanoparticles by seeded RAFT polymerization is rarely reported. Herein, linear block copolymer nanoparticles are first prepared by RAFT dispersion copolymerization of benzyl methacrylate (BzMA) and 2-(2-(n-butyltrithiocarbonate)propionate)ethyl methacrylate (BTPEMA) with different [BzMA]/[BTPEMA] ratios, and employed as seeds for seeded RAFT polymerization of isobornyl acrylate (IBOA) to prepare graft copolymer nanoparticles with different numbers of PIBOA side chains. Comparing with linear triblock copolymers with the same chemical composition, the graft copolymers can promote the formation of higher-order morphologies (e.g., vesicles) under seeded RAFT polymerization conditions. Effects of reaction parameters on the morphology of graft copolymer nanoparticles are investigated in detail, and two morphological phase diagrams are constructed. It is expected that this study will not only expand the scope of seeded RAFT polymerization but also offer new opportunities for the preparation of unique polymer nanoparticles.

Poly(L-lysine)-block-poly(ethylene glycol)-block-poly(L-lysine) triblock copolymers for the preparation of flower micelles and their irreversible hydrogel formation

ABSTRACT Poly(L-lysine)-block-poly(ethylene glycol)-block-poly(L-lysine) (PLys-block-PEG-block-PLys) triblock copolymers formed polyion complex (PIC) with poly(acrylic acid) (PAAc) or sodium poly(styrenesulfonate) (PSS), leading to the formation of flower micelle-type nanoparticles (NanoLys/PAAc or NanoLys/PSS) with tens of nanometers size in water at a polymer concentration of 10 mg/mL. The flower micelles exhibited irreversible temperature-driven sol-gel transitions at physiological ionic strength, even at low polymer concentrations such as 40 mg/mL, making them promising candidates for injectable hydrogel applications. Rheological studies showed that the chain length of PLys segments and the choice of polyanions significantly impacted irreversible hydrogel formation, with PSS being superior to PAAc for the formation. The incorporation of silica gel nanoparticles into the PIC flower micelles also resulted in irreversible gelation phenomena. The highest storage modulus exceeded 10 kPa after gelation, which is sufficient for practical applications. This study demonstrates the potential of these PIC-based hydrogels as biomaterials with tunable properties for biomedical applications.

Preparation and application of multilayered flexible phase change material with high thermal conductivity and high enthalpy

Phase change material (PCM) uses latent heat to store heat and are widely used in thermal management of electronic components. However, endowing PCM with high thermal conductivity and high enthalpy remains a challenge. This study designs a multilayered structure, paraffin (PA)/styrene-b-(ethylene-co-butylene)-b-styrene triblock copolymer (SEBS) (PA/SEBS) and PA/SEBS/expanded graphite (EG) (PA/SEBS/EG) are prepared by melt blending and crosslinked together in sequence, named 0EG@6EG. The results show that the enthalpy value of 0EG@6EG is as high as 167.46 kJ·kg−1, and the thermal conductivity has been improved compared to traditional uniform structure. 0EG@6EG has a certain degree of self-healing ability, and the contact surface between layers could withstand a tensile strength of 0.23 MPa. The passive experiment indicates that the temperature rising rate of 0EG@6EG is 4.08 % higher than that of PA/SEBS/3EG. The active experiment shows that the highest outlet temperature difference between 0EG@6EG and PA/SEBS/3EG is 1.52 °C, and the heat released is 26.73 % higher than that of PA/SEBS/3EG. The optimal thickness ratio between PA/SEBS/0EG to PA/SEBS/6EG in 0EG@6EG is 1.2:0.8, and when the active system contacts with the layer of PA/SEBS/6EG, it is conducive to enhance heat transfer. This work provides a reference for increasing the thermal conductivity of PCM without decreasing enthalpy value.

Self-aggregation behavior of well-defined PEO-based amphiphilic tri-block copolymers and their application as metal detectors

PMMA-b-PEO-b-PMMA tri-block copolymers were synthesized by anionic polymerization technique usingtelechelic1,1-diphenylethylene-terminated poly (ethylene oxide)as macroinitiators and Sec-BuLi four tri-block copolymers of PMMA-b-PEO-b-PMMA with different number average molecular weight ( M ¯ n ) were synthesized, and the structure of the macroinitiators and polymers was confirmed by FTIR. and1H NMR spectroscopic methods. Through the solvent-induced association, the aqueous solutions of PMMA-b-PEO-b-PMMA were formed. After that, hydrodynamic diameter, DLS and TEM were used to study the morphology of the resulting aqueous solutions. The polymer’s self-assembled nanostructures of core-shell flower-like spherical micelles structures were observed. Also, the PMMA hydrophobic content of the tri-block increases steadily and the core size of the micelles decreases significantly, due to reverse micelle formation in which the core is hydrophobic PMMA blocks and the corona is PEO block. This micelle is an excellent detector for metal ions and acts as a reducing agent for them to convert into pure nontoxic nanoparticles.

Anchoring Ties: Improving Environmental Stress Crack Resistance in HDPE with Styrenic Triblock Copolymer

Anchoring Ties: Improving Environmental Stress Crack Resistance in HDPE with Styrenic Triblock Copolymer

Effect of polyacrylic acid‐polypropylene‐polyacrylic acid triblock copolymers with different acid content on mechanical properties of carbon fiber/polypropylene composites

AbstractThe use of polyacrylic acid‐polypropylene‐polyacrylic acid triblock copolymers (PAA‐iPP‐PAA, abbreviated as iPP‐PAA) with different acrylic acid contents (9, 19.5, 29 wt%) as compatibilizers for carbon fiber (CF)/polypropylene (PP) composites and their effect on the tensile properties of the composites were investigated. The addition of iPP‐PAA improved the tensile properties of the CF/PP composites. This enhancement in mechanical properties was considered to be due to the hydrogen bonding network between iPP‐PAAs, which improved the mechanical properties of the matrix resin itself, and to hydrogen bonding between carbon fiber surface and iPP‐PAAs, which improved the interfacial adhesion. A higher acrylic acid content of iPP‐PAA resulted in better interfacial properties; however, excessive acrylic acid content adversely affected the crystallinity and tensile properties of the composite, which suggests that there is an optimum acrylic acid content for the iPP‐PAA. The results indicated that iPP‐PAA is an effective compatibilizer in CF/PP composites, and the iPP‐PAA with the best performance had an acrylic acid content of 19.5%.Highlights PAA‐PP‐PAA copolymers used as compatibilizers for CF/PP composites. Acrylic acid content of PAA‐PP‐PAA varied as 9%, 19.5%, and 29%. Tensile properties of CF/PP composites enhanced by iPP‐PAA addition. Hydrogen bonding improved mechanical properties of matrix resin and CF‐resin adhesion. Optimum acrylic acid content for CF/PP composite was 19.5%.

Precisely Prepared Hierarchical Micelles of Polyfluorene-block-Polythiophene-block-Poly(phenyl isocyanide) via Crystallization-Driven Self-Assembly.

The precise preparation of hierarchical micelles is a fundamental challenge in modern materials science and chemistry. Herein, poly(di-n-hexylfluorene)-block-poly(3-tetraethylene glycol thiophene) (poly(1m-b-2n)) diblock copolymers and polyfluorene-block-polythiophene-block-poly(phenyl isocyanide) triblock copolymers were synthesized using a one-pot process via the sequential addition of corresponding monomers using a Ni(II) complex as a single catalyst for living/controlled polymerization. The crystallization-driven self-assembly of amphiphilic conjugated poly(1m-b-2n) led to the formation of nanofibers with controlled lengths and narrow dispersity. The block copolymers exhibited white, yellow, and red emissions in different self-assembly states. By using uniform poly(1m-b-2n) nanofibers as seeds, introducing the polyfluorene-block-polythiophene-block-poly(phenyl isocyanide) triblock polymer as a unimer in the seed growth process, and adjusting the structure of the poly(phenyl isocyanide) block and the polarity of self-assembly solvent, A-B-A triblock micelles, multiarm branched micelles, and raft micelles were prepared.

Precisely Prepared Hierarchical Micelles of Polyfluorene‐block‐Polythiophene‐block‐Poly(phenyl isocyanide) via Crystallization‐Driven Self‐Assembly

AbstractThe precise preparation of hierarchical micelles is a fundamental challenge in modern materials science and chemistry. Herein, poly(di‐n‐hexylfluorene)‐block‐poly(3‐tetraethylene glycol thiophene) (poly(1m‐b‐2n)) diblock copolymers and polyfluorene‐block‐polythiophene‐block‐poly(phenyl isocyanide) triblock copolymers were synthesized using a one‐pot process via the sequential addition of corresponding monomers using a Ni(II) complex as a single catalyst for living/controlled polymerization. The crystallization‐driven self‐assembly of amphiphilic conjugated poly(1m‐b‐2n) led to the formation of nanofibers with controlled lengths and narrow dispersity. The block copolymers exhibited white, yellow, and red emissions in different self‐assembly states. By using uniform poly(1m‐b‐2n) nanofibers as seeds, introducing the polyfluorene‐block‐polythiophene‐block‐poly(phenyl isocyanide) triblock polymer as a unimer in the seed growth process, and adjusting the structure of the poly(phenyl isocyanide) block and the polarity of self‐assembly solvent, A−B−A triblock micelles, multiarm branched micelles, and raft micelles were prepared.

Next-generation cancer nanotherapeutics: Pluronic® F127 based mixed micelles for enhanced drug delivery.

Cancer, projected to become the second leading cause of mortality globally, underscores the critical need for precise drug delivery systems. Nanotechnology, particularly micelles, has emerged as a promising avenue. These nano-sized colloidal dispersions (< 100 nm) utilize amphiphilic molecules featuring a hydrophilic tail and hydrophobic core, facilitating efficient drug encapsulation and delivery. Pluronic® F127, a triblock copolymer (PEO101-PPO56-PEO101), has emerged as a promising drug carrier due to its non-ionic, less-toxic nature, which prolongs drug circulation time and improves drug delivery across blood-brain and intestinal barriers. Mixed micelles, formed using Pluronic® F127 combined with other polymers, surfactants, and drugs, enhance drug solubility, stability, and targeted delivery. This review highlights the key features of mixed micelles, including enhanced pharmacokinetics and targeting abilities, folic acid (FA) conjugation strategies, superior cytotoxicity with reduced side effects, overcoming multidrug resistance, and versatility across various cancer types and compounds. Additionally, the potential for clinical translation of Pluronic® F127-based mixed micelle in cancer treatment is discussed, addressing current challenges and paving the way for optimized applications.

Visible light responsive heterophase Titania monoliths for the fast and efficient photocatalytic decontamination of organic pollutants

The article reports the synthesis of an ordered mesoporous network of heterophase TiO2 monoliths as a visible light-responsive photocatalyst using tri-block copolymers of Pluronic F108, P123 and F127 as structure-directing agents (SDAs) and temperature-controlled calcination (450–650 °C) has been carried out by direct templating-assisted hydrothermal approach. The structural/surface morphology and topographical properties of the photocatalyst are characterized using FE-SEM-EDAX, HR-TEM-SAED, p-XRD, VB-XPS, PLS, TG/DTA, UV-Vis-DRS, BET/BJH and zeta potential analysis. The undoped heterophase mesoporous TiO2 monoliths with in-built lattice/surface defects exhibit visible light photocatalytic properties, successfully dissipating Reactive Brown 10 (RB-10) dye. The influence of physicochemical parameters, such as SDAs, temperature, pH, dye concentration, catalyst dosage, photosensitizers and light intensities, are optimized for maximum photocatalytic performance at a shorter timespan. The F127-assisted mesoporous TiO2 monolith (550 °C) exhibits superior degradation kinetics (15 min) for RB-10 dye solution (20 ppm) at pH 2.0–3.0 using a photocatalyst dosage of 50 mg and 2 mM of KBrO3, irradiated with 150 W/cm2 tungsten lamp. The photocatalysts are fabricated without complicated chemical modifications and display topmost efficiency in quickly decontaminating persistent pollutants. The photoproducts from RB-10 photocatalytic degradation are investigated using HR-MS analysis. The photocatalyst can be reused efficiently for six cycles, even under extreme conditions.

Functional interleukin-4 releasing microparticles impact THP-1 differentiated macrophage phenotype.

Macrophage cell therapies offer potential treatment in inflammatory diseases due to their ability to mobilize and stimulate their environment. However, successful treatment requires a pro-regenerative macrophage phenotype to be retained in vivo. Polymeric microparticles may provide a potential route to direct and sustain macrophage phenotype. Interleukin-4 (IL-4) is the most commonly used cytokine for in vitro modulation towards M2a macrophage phenotype. We designed IL-4 encapsulated microparticles to investigate the impact of drug release kinetics and developed a robust human peripheral blood monocyte cell (THP-1) in vitro assay to assess functional IL-4 release upon macrophage phenotype. IL-4 was encapsulated with human serum albumin (HSA) in microparticles fabricated from a blend of PLGA and a PLGA-PEG-PLGA triblock copolymer. Functional release of IL-4 and HSA over different time periods was measured using ELISAs. THP-1 differentiated macrophages were cultured either in direct contact with microparticles or indirectly through transwells. The immunomodulatory impact of microparticles on THP-1 cells were measured using ELISA and qPCR. IL-4 release kinetics fit with the first-order release kinetics model, indicating concentration dependent release. IL-4/HSA encapsulated microparticles modulated THP-1 differentiated macrophages towards pro-immunoregulatory subgroups. This strategy provides a novel approach in drug carrier development for in vitro assessments of macrophage phenotype to inform development of targeted therapies for inflammation and immune modulation.

Photoinduced Anisotropy in Thin Films of Azobenzene-Containing Liquid Crystalline Supramolecular Complexes of Various Polymer Architecture.

Light patternable colorless liquid crystalline (LC) polymers are promising materials for functional photonic devices with broad applications in optical communication, diffractive optics, and displays. This work reports photoinduced optical anisotropy in thin films of azobenzene-containing (Azo) LC block copolymer supramolecular complexes, which can be decolorized after light patterning providing colorless patterned birefringent polymer films. The supramolecular complexes are prepared via intermolecular pyridine-phenol hydrogen bonding between a low-molecular-weight Azo phenol and host LC AB diblock and ABA triblock copolymers consisted of LC phenylbenzoate (PhM) blocks and poly(vinylpyridine) units. The molecular architecture of the host polymers and the morphological pattern formed by the complexes can affect orientational behavior of Azo groups under irradiation with linearly polarized light. Photoorientation of hydrogen-bonded Azo groups is accompanied by the cooperative orientation of non-photochromic PhM units, which form individual microphases and stabilize the orientation of Azo groups. This effect is specific for block copolymer complexes and it is absent for random copolymer complex, which is used as a reference sample. Optical anisotropy induced in films of the block copolymer complexes can be amplified by heating above the glass transition temperature and subsequent rinsing with diethyl ether allows colorless birefringent polymer films to be prepared.

Synthesis of high-ordered mesoporous aluminosilica monoliths using triblock copolymer and application in the water purification

Mesoporous aluminosilica particulates (MASP) offer a high surface area and specific structural properties that make them effective for adsorbing specific contaminants from drinking water. The MASP’s surface characteristics were studied by SEM, TEM, Mapping-EDX, and BET analysis. Through the use of a batch adsorption approach, this work sought to examine the adsorption behavior of MASP sorbent towards Cd(II) ions at different pH values, time intervals, sorbent doses, and temperatures. MASP’s maximal capacity for Cd(II) ions uptake was 16.5 mg/g at pH 6.5, 25 °C, 0.1 g dose, and 5 h of sorption time. The pseudo-first-order model provided a good description of the uptake process. The best-fitting isotherm was found to be the Langmuir and Redlich–Peterson isotherm. The method came out to be exothermic and spontaneous by thermodynamic analysis. MASP demonstrates durability and reusability during over ten regeneration cycles.

Amorphous solid dispersions of amphiphilic polymer excipients and indomethacin prepared by hot melt extrusion

Improving the solubility of poorly water-soluble drugs is essential for enhancing bioavailability, formulation flexibility and reducing patient-to-patient variability. The preparation of amorphous solid dispersions (ASDs) is an attractive strategy to formulate such drugs, leading to higher apparent water solubility and therefore higher bioavailability. For such ASDs, water-soluble polymer excipients, such as poly(vinyl pyrrolidone) (PVP) or poly(vinyl pyrrolidone-co-vinyl acetate) (P(VP-co-VA)), are employed to solubilize and stabilize the drug against crystallization. We posit that polymers bearing tertiary amides are particularly well suited to stabilizing drugs containing H-bond donors, as they offer strong H-bonding potential between the polymer and drug. The aim of this study was to compare new and established polymers with tertiary amides as excipients for ASDs. Experimental amphiphilic ABA triblock copolymers comprising poly(2-methyl-2-oxazoline) (pMeOx), poly(2-butyl-2-oxazoline) (pBuOx) and poly(2-butyl-2-oxazine) (pBuOzi) blocks, were compared with the established excipients, PVP and P(VP-co-VA). ASDs with indomethacin as the model drug were prepared at high drug loadings via hot melt extrusion. The extrudates were studied with DSC and PXRD, revealing the ASDs to be fully amorphous up to 75wt% indomethacin, independent of the polymer used. 13C CPMAS NMR provided insights into intermolecular associations as a function of drug loading, and suggested the presence of drug dimers at 75wt% drug loading in pMeOx-pBuOzi-pMeOx and pMeOx-pBuOx-pMeOx, which could affect physical stability. Independent of the polymers, the solid-state form of the drug in the ASD was found to affect the dissolution profile of the samples, insofar as the samples containing crystalline indomethacin showed slower dissolution than the fully amorphous ones. This study shows that the polymers comprising poly(2-oxazoline) and poly(2-oxazine) are effective polymers for ASD preparation, similar to PVP and P(VP-co-VA) which merits further investigations into these novel polymers for formulating ASDs.

Improving CO2 separation performances of Styrene-Butadiene-Styrene Triblock Copolymer Membranes by tunning its Microstructure via varying solvents and/or non-solvents

Microstructure in block copolymers has a critical impact on CO2 separation performances. In this work, styrene-butadiene-styrene (SBS) triblock copolymer membranes were made using various solvent/non-solvent combinations. It was found that the solvents changed their microstructure thus the CO2 separation performances were changed accordingly. CO2 permeability in the range of 203.4 to 282, and CO2/N2 selectivity in the range of 15.8 to 22.7. The highest CO2 separation performance (PCO2 282 Barrer with CO2/N2 selectivity of 20.5) was obtained using cyclohexane (CYH) as solvent. Furthermore, the CO2 separation performances of the membrane can be further improved by DI water-induced microstructure rearrangement (PCO2 343.5 Barrer and CO2/N2 selectivity 17.9). In addition, it was found that the rearranged membrane demonstrated stable gas separation performance after the membrane was stored under ambient conditions for about 120 days, clearly denoting that the CO2 separation performances of block copolymeric membranes can be tuned by varying the solvents/non-solvents.

A microphase-separated structure of polystyrene-b-polyisoprene-b-polystyrene triblock copolymers prepared via shear-press and injection molding methods during uniaxial deformation

The influence of the preparation method on the initial structure and deformation behavior of polystyrene (PS) - polyisoprene (PI) - PS (SIS) triblock copolymer elastomers was investigated using small-angle X-ray scattering (SAXS) and wide-angle X-ray diffraction (WAXD). Shear pressing (SP) and injection molding (IM) were used as the preparation methods. The samples exhibited a microphase-separated structure, in which the PS cylinders were packed in a hexagonal lattice for the entire sample. SP-SIS possessed a higher degree of microphase separation (DMPS) and an ordering of a microphase-separated structure (OMPSS), and lower degree of the PS cylinder orientation (DCO) than IM-SIS. Uniaxial tensile testing was performed along the parallel (//) and perpendicular (–|) directions to the PS cylinder orientation combining in situ SAXS/WAXD measurements. Young’s modulus and tensile strength of IM-SIS were lager and smaller than those of SP-SIS. A change in the PS cylinder orientation, which occurs for –| stretching, of IM-SIS occurred at larger strain than SP-SIS, indicating that the orientation of highly ordered PS cylinders are difficult to be changed due to their larger domains. It was found that the DCO relates to Young's modulus, yielding, and change in the PS cylinder orientation, while the OMPSS and DMPS relate to tensile strength.

A macromolecule infliximab loaded reverse nanomicelles-based transdermal hydrogel: An innovative approach against rheumatoid arthritis

Infliximab (IFX) is used as a biotherapeutic agent for the treatment of rheumatoid arthritis (RA); however, its biological activity is lost orally because of variations in gastric pH and enzymatic degradation, and reduced bioavailability. The authors have tried to improve the efficacy of macromolecule delivery through transdermal route. Polycaprolactone-Polyethylene glycol-Polycaprolactone (PCL-PEG-PCL) triblock copolymer previously synthesized and was used as an efficient carrier for the preparation of IFX loaded reverse nanomicelles (IFX-RNMs). The RNMs were fabricated via nanoprecipitation technique, characterized and then were incorporated into a Carbopol-based hydrogel with eucalyptus oil (EO) as a penetration enhancer. The optimized RNMs had a particle size of 72.32 nm and an encapsulation efficiency of 83 %. In vitro release, exhibited a sustained pattern of IFX from the prepared carrier system, ex-vivo skin permeation and fluorescence microscopic studies revealed that IFX-RNMs loaded hydrogel with EO markedly improved permeation. An in vivo study was carried out on a CFA-induced RA mice model that revealed significant improvements in the results of behavioral parameters, biochemical assays, histopathological and radiological analysis. Overall, the results concluded that the IFX-RNMs loaded hydrogel can be used as a suitable approach for treating RA.

Rational Synthesis of Spongy Fe3N@N-Doped Carbon Nanorods with Controlled Topography and Porosity for Enhanced Energy Storage Anodes in Lithium-Ion Batteries.

Iron nitrides with the merits of high theoretical capacities, cost-effectiveness, and good electronic/ionic conductivity have been recognized as attractive anode candidates for lithium-ion batteries (LIBs). Carbon compositing, pore engineering, and nanostructure construction have proved to be effective strategies to prepare high-performance metal nitride anodes for LIBs. Herein, we synthesized a series of Fe3N-embedded and N-doped carbon nanorods (Fe3N@NCNR) with a hierarchical porous system and controllable topography by metal-catalyzed graphitization-nitridization of the Fe(III)-triazole framework (Fe-MOF) and thermal evaporation of the triblock copolymer F127 template assembled in Fe-MOF via hydrogen bonding interaction, followed by the air oxidation and urea-assisted ammonolysis processes. The Fe3N@NCNR as anodes for LIBs display extraordinary lithium storage capabilities with a high reversible capacity of 830 mA h g-1 at 0.1 C, a good rate performance of 576 mAh g-1 at 5 C, and a long-term cycling stability of 742 mA h g-1 over 600 cycles at 1 C. Such outstanding performance benefits from the spongy carbon nanorods with rich macropores for rapid electronic/ionic transport and effective accommodation of electrode volume expansion, abundant N-doped meso-/microporous carbon for the additional storage of Li+ via capacitive effect, and the efficient utilization of Fe3N nanoparticles uniformly distributed through carbon nanorods. Importantly, this work introduces an effective strategy to construct superior performance nitride anodes from MOF surfactants based on hydrogen bonding-driven interface self-assembly and provides insight into the preparation of highly efficient nanoarchitectures for Li+ storage.