Sports-related injuries remain a significant problem for collegiate baseball players. Although some studies reported the epidemiology of sports-related injuries among collegiate baseball players, the latest information on sport-related injuries should be provided. To examine the current trends of sports-related injuries among collegiate baseball players in the Pacific 12 (PAC-12) Conference. Descriptive epidemiology study. Demographic and injury data were obtained from a database of the PAC-12 Health Analytics Program between 2016 and 2021. Injury incidence, type, mechanism, and outcome were analyzed. The annual incidence of injuries was defined as the number of injuries per total players for 1 year. Detailed reports of the 20 most common specific diagnoses were generated. A total of 1434 sports-related injuries occurred in 6 years, with the number increasing from 2016 (n = 75; incidence, 8.5 per 100 player-years) to 2021 (n = 378; incidence, 43 per 100 player-years). Most of the injuries occurred in pitchers (33.6%), were acute (76.6%), resulted in missed time (68.8%), and were new injuries (86.9%). In addition, most injuries were caused by noncontact events (53.2%) and occurred during in-season games (39.9%) and practice (47.4%). Only 1.3% of sports-related injuries did not result in a return to the previous activity level. Rotator cuff tendon injuries were the most common specific diagnoses (n = 98), followed by ulnar collateral ligament (UCL) injuries (n = 63), hamstring muscle strains (n = 60), ankle ligament sprains (n = 46), and hand/wrist fractures (n = 40). UCL injuries had the highest proportion of surgical interventions (41.3% of all UCL injuries) and the longest days to clearance (167 ± 197 days) among the 20 most common diagnoses. The number of sports-related injuries among PAC-12 collegiate baseball players has increased by approximately 5 times over the past 6 years. Rotator cuff tendon injuries followed by UCL injuries, hamstring muscle strains, ankle ligament sprains, and hand/wrist fractures are the most common specific diagnoses among this cohort of collegiate baseball players. Of the 20 most common specific diagnoses, UCL injuries most often require surgical interventions and had the longest return to playtime.
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