Treatment Techniques Research Articles

Sustainable Sludge Management in China: Quantifying GHG Emissions and Exploring Its Reduction Strategies

This study aims to evaluate the emissions of greenhouse gases (GHGs) stemming from the sludge treatment sector in China and to investigate the feasibility of novel technologies in curtailing these emissions, with the aim of fostering sustainable sludge management methodologies. Employing a life-cycle assessment (LCA) methodology, the research computed the comprehensive GHG emissions resulting from sludge treatment, taking into consideration diverse elements such as treatment techniques (e.g., landfills, incineration, and land application) and the geographical variations among China’s 660 municipalities. Findings indicate that the total amount of GHG emissions from sludge treatment amounted to 18.54 Mt CO2-eq in 2017, with incineration registering the highest emissions (10,011.53 kg CO2-eq/t dry sludge (DS)), followed by landfills (717.51 kg CO2-eq/t DS) and land application (276.41 kg CO2-eq/t DS). The geographical dispersion of emissions characteristics reveal notable regional disparities, with the top 1% of cities responsible for 34.2% of the overall emissions. The concentration of emissions in the top 1 percent of cities underscores the necessity for tailored mitigation measures that consider localized sustainable development challenges. Principal component analysis (PCA) demonstrates that economic determinants and treatment scales exert substantial influence on emissions, underscoring the imperative of aligning Sustainable Development Goals (SDGs) with economic advancement. To curtail the carbon footprint associated with sludge treatment and enhance sustainability, the study evaluated the emission mitigation potential and expenses of diverse technologies, encompassing thermal conversion, anaerobic digestion, hydrothermal treatment, and wet oxidation. These technologies have the capacity to slash GHG emissions by 0.09–0.46 t CO2-eq/t DS in comparison to traditional approaches, while concurrently advancing resource recuperation and principles of circular economy. For instance, gasification could diminish GHG emissions by 0.33–0.46 t CO2-eq/t DS, whereas anaerobic digestion could yield reductions of 0.09–0.30 t CO2-eq/t DS. The implementation of these innovative technologies across 660 Chinese municipalities could potentially curtail total GHG emissions from sludge treatment by 15–40%. Nevertheless, further enhancements are imperative to refine their environmental and economic efficiency and guarantee enduring sustainability. By deploying these technologies and embracing optimization tactics, China’s sludge treatment sector can make a substantial contribution towards attaining national carbon neutrality objectives and advancing sustainable development.

Novel single-entry point injection technique for masseter hypertrophy treatment using botulinum neurotoxin based on patient-reported comfort.

Botulinum neurotoxin (BoNT) injections are widely used for the treatment of masseter muscle hypertrophy in Southeast Asia. However, there remains a lack of consensus regarding the optimal injection technique. This study aimed to compare the efficacy and patient discomfort associated with single-entry point injections versus multiple three-point injections for masseter muscle hypertrophy treatment with BoNT. Sixteen participants, comprising both male and female Korean adults aged 22-63, were enrolled in the study. On the left side of the face, single-entry point injections were administered, followed by multidirectional injections, while on the right side, three-point injections were given. Pain intensity during the procedure was assessed using visual analogue scale scores. Our results revealed that participants experienced lower levels of pain with single-entry point injections compared to three-point injections (average visual analogue scores of 3.31 and 5.19, respectively). These findings highlight the potential benefits of single-entry point injections in reducing patient discomfort during masseter muscle hypertrophy treatment with BoNT. We advocate for further research to validate these findings and encourage practitioners to consider single-entry point injections as a viable option for enhancing treatment outcomes in their clinical practice.

De‐Intercalation of Iodoplumbate(DMSO)x Complex for Uniaxially Oriented Halide Perovskite Thin‐Film Solar Cells

AbstractOrganic lead halide perovskite solar cells (PSCs) have become a viable alternative for next‐generation photovoltaic systems. The significance of reproducibly processing perovskite with less defects comes from the fact that imperfections have a major impact on the solar cell's performance and long‐term stability. Although it is well known that cautious precursor processing has a significant influence on perovskite defect generation, there haven't been extensive investigations on the serial associations between precursor processing, perovskite orientation, and defect generation in PSCs. Making use of a unique precursor chemistry treatment technique that facilitates uniaxially oriented perovskite growth, it is aimed to mitigate defects of sequentially spin‐coated perovskite. Through the temperature‐dependent configurational entropic effect on coordination between iodoplumbate and dimethylsulfoxide (DMSO), a DMSO de‐intercalation processing method is developed. This method enables the induction of uniaxially‐oriented α‐FA0.9MA0.1PbI3‐xBrx (FA: formamidnium, MA: methylammomnium, x < 0.13) perovskite growth parallel to substrates. As a result, this processing delivered significant advances in power conversion efficiency (24.02%) and ambient operational stability under light. This straightforward technique provides a accesible process for producing efficient and stable perovskite solar cells, enabling uniaxially oriented perovskite fabrication without complicated procedures or additional substances.

Clinical and radiological variants of the nail–patella syndrome: Why is it important to make a correct diagnosis?

BACKGROUND: Nail–patella syndrome is an autosomal dominant disease caused by LMX1B mutations, characterized by a combination of dermatological and musculoskeletal abnormalities. The classic tetrad of the nail–patella syndrome includes hypoplasia of the nail plates, absence or hypoplasia of the patella, elbow joint contractures, often accompanied by posterior subluxation of the radial head, presence of “iliac horns” on radiographs of the pelvic bones, and renal changes. However, its diagnosis and treatment are not described in sufficient detail in domestic and foreign literature. AIM: This study aimed to analyze the variability of clinical and radiological manifestations in children with nail–patella syndrome. MATERIALS AND METHODS: Nine patients with nail–patella syndrome were examined and treated (aged 4 months to 14 years). All children presented to the H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery with a diagnosis of congenital multiple arthrogryposis. The examination results excluded this diagnosis. The diagnosis of nail–patella syndrome has been verified. RESULTS: Various variants of the nail–patella syndrome have been identified, with lesions to only the elbow joints (n = 3), damage to the upper and lower extremities (n = 5), and damage to only the lower extremities (n = 1). All patients had hypoplasia of fingernail plates. However, the pathognomonic sign – “iliac horns” on radiographs of the pelvic bones – was noted only in 33% of cases. Regarding functional disorders of the kidneys, proteinuria was observed in one patient, which appeared at the age of 15 years. In two cases, the parents suffered from this disease. A genetic examination was performed in three patients: a pathogenic variant in LMX1B was detected in a heterozygous state. All patients underwent conservative treatment for knee and elbow joint contractures and foot deformities. When casting, the presence of dislocation of the radial head or patella was considered. Surgical treatment was performed on five patients. The results of surgery on the lower extremities (knee contractures, foot deformities, and hip dislocation) were good in 87% of the cases. Recurrence of flexion contractures in the elbow joints was observed both after conservative and after surgical treatment in all cases; however, their severity varied. CONCLUSIONS: Clinical observations were considered to attract the attention of doctors of different specialties to a rare pathology. Moreover, a molecular genetic study is recommended for the timely diagnosis of the nail–patella syndrome, determining the treatment techniques and disease prognosis.

Dosimetric and radiobiological advantages from deep inspiration breath-hold and free breath technique for left-sided breast radiation using 3DCRT, IMRT and Rapid Arc methods-a complete assessment.

The verification and use of the best treatment approach using 3D conformal radiation therapy (3DCRT), intensity modulated radiation therapy (IMRT) and Rapid Arc methods for left breast radiation with dosimetric and radiobiological characteristics. The use of custom-built Python software for the estimation and comparison of volume, mean dose, maximum dose, monitor units and normal tissue integral dose along with radiobiological parameters such as NTCP, tumor control probability, equivalent uniform dose and LKB's effective volume from 3DCRT, IMRT and Rapid Arc planning with deep inspiration with breath holding (DIBH) and free breadth (FB) techniques. Volume growth of three-fourth in DIBH compared with FB causes a decrease in cardiac doses and complications because the left lung expands, pulling the heart away from the chest wall and the treatment area. A tiny area of the left lung was exposed during treatment, which reduced the mean dose. There was little difference in the treatment approaches because the spinal cord was immobile in both techniques. Rapid Arc is the unmatched modality for left-sided breast irradiation with significant patient breath-hold, as shown by the comparison of dosimetric and radiobiological parameters from treatment techniques with a deep inspiration breath-hold approach.

Effect of a peer-led emergency department behavioral intervention on non-fatal opioid overdose: 18-month outcome in the Navigator randomized controlled trial.

Emergency departments (EDs) provide an opportunity to identify people at risk of overdose and reduce the risk. We evaluated the effect of an ED behavioral intervention delivered by peer recovery support specialists (PRSSs) on non-fatal opioid overdose. Two-arm, randomized trial. Two EDs in Rhode Island, USA. ED patients presenting with an opioid overdose, complications of opioid use disorder or a recent history of opioid overdose (November 2018-May 2021). Among 648 participants, the mean age was 36.9years, 68.2% were male and 68.5% were White. Participants were randomized to receive a behavioral intervention from a PRSS (n = 323) or a licensed clinical social worker (LICSW) (n = 325). PRSS and LICSW used evidence-based interviewing and intervention techniques, informed by their lived experience (PRSS) or clinical theory and practice (LICSW). We identified non-fatal opioid overdoses in the 18 months following the ED visit through linkage to statewide emergency medical services data using a validated case definition. The primary outcome was any non-fatal opioid overdose during the 18-month follow-up period. Among 323 participants randomized to the PRSS arm, 81 (25.1%) had a non-fatal opioid overdose during follow-up, compared with 95 (29.2%) of 325 participants randomized to the LICSW arm (P = 0.24). There was no statistically significant difference in the effectiveness of randomization to the PRSS arm versus the LICSW arm on the risk of non-fatal opioid overdose, adjusting for the history of previous overdose (relative risk = 0.86, 95% confidence interval = 0.67-1.11). In Rhode Island, USA, over one-in-four emergency department patients at high risk of overdose experience a non-fatal opioid overdose in the 18 months post-discharge. We found no evidence that the risk of non-fatal opioid overdose differs for emergency department patients receiving a behavioral intervention from a peer recovery support specialist versus a licensed clinical social worker.

Evaluating the predictive potential of RSM and ANN Techniques in treatment of greywater-syrup mixture using Ekowe clay-PEM microbial fuel cell

Evaluating the predictive potential of RSM and ANN Techniques in treatment of greywater-syrup mixture using Ekowe clay-PEM microbial fuel cell

Evaluating the predictive potential of RSM and ANN Techniques in treatment of greywater-syrup mixture using Ekowe clay-PEM microbial fuel cell

Evaluating the predictive potential of RSM and ANN Techniques in treatment of greywater-syrup mixture using Ekowe clay-PEM microbial fuel cell

Reducing Fear and Enhancing Aesthetics: Orthodontic Management with Video Self-Modeling in an Adolescent with Autism Spectrum Disorder

Abstract Introduction Autism spectrum disorder (ASD) presents challenges in social interaction and communication, particularly in the context of orthodontic treatment where patients may experience heightened anxiety. This case report introduces an innovative approach that utilizes video self-modeling (VSM) to address these challenges and enhance the orthodontic treatment experience for adolescents with ASD. Case Report An 11-year-old female patient with ASD required orthodontic treatment. Conventional behavioral guidance techniques were unsuccessful because of the patient's anxiety and sensory sensitivity. Utilizing VSM, we crafted personalized video content to illustrate the dental procedure, significantly alleviating patient's fear and anxiety. This approach led to the successful completion of her orthodontic treatment. Conclusion This case report underscores the effectiveness of VSM as a valuable behavioral guidance technique in orthodontic treatment for adolescents with ASD. By alleviating anxiety and fear, VSM has the potential to significantly enhance the dental care experience and promote improved oral health and well-being in this specific patient population.

Cost-effectiveness of approaches to cervical cancer screening in Malawi: comparison of frequencies, lesion treatment techniques, and risk-stratified approaches

BackgroundRecently-updated global guidelines for cervical cancer screening incorporated new technologies—most significantly, the inclusion of HPV DNA detection as a primary screening test—but leave many implementation decisions at countries’ discretion. We sought to develop recommendations for Malawi as a test case since it has the second-highest cervical cancer burden globally and high HIV prevalence. We incorporated updated epidemiologic data, the full range of ablation methods recommended, and a more nuanced representation of how HIV status intersects with cervical cancer risk and exposure to screening to model outcomes of different approaches to screening.MethodsUsing a Markov model, we estimate the relative health outcomes and costs of different approaches to cervical cancer screening among Malawian women. The model was parameterized using published data, and focused on comparing “triage” approaches—i.e., lesion treatment (cryotherapy or thermocoagulation) at differing frequencies and varying by HIV status. Health outcomes were quality-adjusted life years (QALYs) and deaths averted. The model was built using TreeAge Pro software.ResultsThermocoagulation was more cost-effective than cryotherapy at all screening frequencies. Screening women once per decade would avert substantially more deaths than screening only once per lifetime, at relatively little additional cost. Moreover, at this frequency, it would be advisable to ensure that all women who screen positive receive treatment (rather than investing in further increases in screening frequency): for a similar gain in QALYs, it would cost more than four times as much to implement once-per-5 years screening with only 50% of women treated versus once-per-decade screening with 100% of women treated. Stratified screening schedules by HIV status was found to be an optimal approach.ConclusionsThese results add new evidence about cost-effective approaches to cervical cancer screening in low-income countries. At relatively infrequent screening intervals, if resources are limited, it would be more cost-effective to invest in scaling up thermocoagulation for treatment before increasing the recommended screening frequency. In Malawi or countries in a similar stage of the HIV epidemic, a stratified approach that prioritizes more frequent screening for women living with HIV may be more cost-effective than population-wide recommendations that are HIV status neutral.

An Update on the Association of COVID-19 and Neuropsychiatric Disorders

Abstract: The COVID-19 pandemic and lockdown have sparked global terror and apprehension. This phenomenon has led to short-term as well as long-term psychosocial and mental health implications for all. This paper aims at reviewing the prevalence, pathophysiology and treatment of various neuropsychiatric disorders in the pandemic era. We conducted a review and collected articles before and during the COVID-19 pandemic and presented a comparative study of the prevalence of neuropsychiatric disorders before COVID-19 and during COVID-19 pandemic. We selected articles and thematically organized them. Prevalence, pathophysiology, and treatment techniques were studied. We can conclude that the time has come to ensure that the special opportunities presented by this pandemic can translate advocacy to resourcing, ensuring that actionable outputs are delivered for better mental health services. This is necessary given the ground level as well as grassroots support for increased funding for mental health services as well as the apparent desire across all sectors for improved service provision. Longitudinal investigations are required for the assessment of long-lived psychological disorders of the COVID-19 pandemic. The findings need comprehensive evaluation and rehabilitation post-COVID-19 to promote quality of life.

Dose Distribution Three-Dimensional Conformal Radiation Therapy (3DCRT) With 2 And 4 Directions in Treatment Planning System for Cervical Cancer Cases

Cervical cancer which attacks the cervix is triggered by a virus called human papilloma virus (HPV). One effective treatment method for cervical cancer is external radiotherapy using a Linear Accelerator (Linac). This research aims to obtain radiation dose distribution by comparing the effectiveness of two treatment techniques cervical cancer, through Conformity Index (CI), Homogenity Index (HI), and radiation protection against Organ at Risk (OAR) in accordance with QUANTEC rules. The techniques used is Three Dimensional Conformal Radiation Therapy (3DCRT) with 2 directions of irradiation (anterior – posterior) and 4 directions of irradiation (box). Research data was obtained from 15 images of cervical cancer patients who have contoured by a Radiation Onkology Doctor at Indriati Hospital Solo Baru. From the result of the research, it can be said that the 3DCRT technique with 4 directions It can be seen from a higher Conformity Index (CI) value indicating a better level of conformity, and a lower Homogenity Index (HI) value indicating a higher level of homogenity. In addition, the 3DCRT technique with 4 directions of irradiation is also considered more effective in protecting OAR compared to 2 directions of irradiation.

Dose Distribution Three-Dimensional Conformal Radiation Therapy (3DCRT) With 2 And 4 Directions in Treatment Planning System for Cervical Cancer Cases

Cervical cancer which attacks the cervix is triggered by a virus called human papilloma virus (HPV). One effective treatment method for cervical cancer is external radiotherapy using a Linear Accelerator (Linac). This research aims to obtain radiation dose distribution by comparing the effectiveness of two treatment techniques cervical cancer, through Conformity Index (CI), Homogenity Index (HI), and radiation protection against Organ at Risk (OAR) in accordance with QUANTEC rules. The techniques used is Three Dimensional Conformal Radiation Therapy (3DCRT) with 2 directions of irradiation (anterior – posterior) and 4 directions of irradiation (box). Research data was obtained from 15 images of cervical cancer patients who have contoured by a Radiation Onkology Doctor at Indriati Hospital Solo Baru. From the result of the research, it can be said that the 3DCRT technique with 4 directions It can be seen from a higher Conformity Index (CI) value indicating a better level of conformity, and a lower Homogenity Index (HI) value indicating a higher level of homogenity. In addition, the 3DCRT technique with 4 directions of irradiation is also considered more effective in protecting OAR compared to 2 directions of irradiation.

Overview of the low-cost technologies for household water treatment in developing countries

ABSTRACT This study explored various low-cost water treatment technologies that are used to minimize levels of pathogens and contaminants in raw water. The paper focused on techniques such as cloth filtration, boiling, chlorination, and solar water disinfection. In the communities, cloth filtration is applied as the initial step of treating raw water with the proper choice of cloth fabrics followed by either boiling, chlorination or solar water disinfection. In low-income communities with unclean burning fuel sources, boiling was found to be the preferred method. Chlorination was also a popular technique associated with the challenges of low or high levels of free chlorine at the point of use and disinfection by-products. Solar water disinfection required optimal residence time and detection sensors for microorganism inactivation. Overall, the paper provided valuable insights into the different low-cost water treatment techniques that are commonly used for household applications, particularly in developing countries.

Extra-articular proximal tibia fracture fixation with locked plating versus intramedullary nailing: A meta-analysis

ObjectivesThis study compared outcomes of locked plating (LP) versus intramedullary nailing (IMN) techniques for treatment of extra-articular proximal-third tibia fractures. MethodsData Sources: PubMed, Ovid MEDLINE Study SelectionStudies were included if they compared LP and IMN fixation for proximal one third tibial shaft fractures without articular extension or with simple articular extension into the tibial plateau. Minimum 1 year of clinical and radiographic follow up was used. Data ExtractionOutcomes assessed included operative duration, postoperative knee range of motion (ROM), union outcomes (time to union, nonunion, malunion, delayed union), and incidence of postoperative complications (superficial and deep infection, secondary surgical intervention, compartment syndrome). Data SynthesisSeparate random-effects meta-analyses were conducted for each outcome. For categorical data, relative risks were used whereas the standardized mean difference was used for continuous variables, with corresponding 95 % confidence intervals. Results7 studies were included reporting the outcomes of 319 patients treated with LP and 300 treated with IMN. IMN fixation had significantly shorter time to union (p = 0.049) and lower risk for superficial infection (p = 0.028). However, LP conferred a significantly lower risk for malunion (p = 0.017) and postoperative compartment syndrome (p = 0.018). ConclusionIMN demonstrated significantly shorter time to union and lower risk of superficial infection when treating extra-articular proximal tibia fractures, while LP fixation demonstrated significantly lower risk for malunion and postoperative compartment syndrome. Although successful results can be achieved with good technique in LP and IMN fixation, a significant complication profile exists with these fractures regardless of construct choice. Level of EvidenceTherapeutic Level III

Exploring the added effect of three recommender system techniques in mobile health interventions for physical activity: a longitudinal randomized controlled trial

Exploring the added effect of three recommender system techniques in mobile health interventions for physical activity: a longitudinal randomized controlled trial

Noteworthy synthesis strategies and applications of metal-organic frameworks for the removal of emerging water pollutants from aqueous environment

17 global Sustainable Development Goals (SDGs) were established through the adoption of the 2030 Agenda for Sustainable Development by all United Nations members. Clean water and sanitation (SDG 6) and industry, innovation, and infrastructure (SDG 9) are the SDGs focus of this work. Of late, various new companies delivering metal-organic frameworks (MOFs) have blossomed and moved the field of adsorption utilizing MOFs to another stage. Inside this unique circumstance, this article aims to catch recent advancements in the field of MOFs and the utilizations of MOFs relate to the expulsion of arising contaminations that present huge difficulties to water quality because of their steadiness and possible damage to environments and human wellbeing. Customary water treatment techniques regularly neglect to eliminate these poisons, requiring the advancement of novel methodologies. This study overviews engineering techniques for controlling MOF characteristics for better flexibility, stability, and surface area. A current report on MOFs gathered new perspectives that are amicably discussed in emergent technologies and extreme applications towards environmental sectors. Various applications in many fields that exploit MOFs are being fostered, including gas storage, fluid separation, adsorbents, catalysis, medication delivery, and sensor utilizations. The surface area of a wide range of MOFs ranges from 103 to 104 m2/g, which exceeds the standard permeability of several material designs. MOFs with extremely durable porosity are more significant in their assortment and variety than other classes of porous materials. The work outlines the difficulties encountered in the synthesis steps and suggests ways to make use of MOFs' value in a variety of contexts. This caters to creating multivariate systems enclosed with numerous functionalities, leading to the synthesis of MOFs that offer a synergistic blend of in-built properties and exclusive applications. Additionally, the MOF-related future development opportunities and challenges are discussed.

Noteworthy synthesis strategies and applications of metal-organic frameworks for the removal of emerging water pollutants from aqueous environment

17 global Sustainable Development Goals (SDGs) were established through the adoption of the 2030 Agenda for Sustainable Development by all United Nations members. Clean water and sanitation (SDG 6) and industry, innovation, and infrastructure (SDG 9) are the SDGs focus of this work. Of late, various new companies delivering metal-organic frameworks (MOFs) have blossomed and moved the field of adsorption utilizing MOFs to another stage. Inside this unique circumstance, this article aims to catch recent advancements in the field of MOFs and the utilizations of MOFs relate to the expulsion of arising contaminations that present huge difficulties to water quality because of their steadiness and possible damage to environments and human wellbeing. Customary water treatment techniques regularly neglect to eliminate these poisons, requiring the advancement of novel methodologies. This study overviews engineering techniques for controlling MOF characteristics for better flexibility, stability, and surface area. A current report on MOFs gathered new perspectives that are amicably discussed in emergent technologies and extreme applications towards environmental sectors. Various applications in many fields that exploit MOFs are being fostered, including gas storage, fluid separation, adsorbents, catalysis, medication delivery, and sensor utilizations. The surface area of a wide range of MOFs ranges from 103 to 104 m2/g, which exceeds the standard permeability of several material designs. MOFs with extremely durable porosity are more significant in their assortment and variety than other classes of porous materials. The work outlines the difficulties encountered in the synthesis steps and suggests ways to make use of MOFs' value in a variety of contexts. This caters to creating multivariate systems enclosed with numerous functionalities, leading to the synthesis of MOFs that offer a synergistic blend of in-built properties and exclusive applications. Additionally, the MOF-related future development opportunities and challenges are discussed.

Effect of natural Sapindus mukorossi treatment process on bio-waste bagasse fibers for biocomposite fabrication and application purposes

In the present research investigation, a novel natural treatment technique consists of Sapindus mukorossi and citric acid was used to treat the fibers as an alternative to conventional chemical treatments that can have adverse effects on both the environment and human health. The fibers were treated with natural solution for varying time intervals of 24, 48, 72, 96 and 120 h, and reinforced with poly-lactic acid using injection moulding machine. The thermal, mechanical and moisture absorption properties of developed naturally treated biocomposites were examined through FTIR spectroscopy, thermogravimetric analysis, and mechanical analysis to explore the optimal treatment period. The optimal treatment period for the fibers was determined to be 72 h, during which overall properties of biocomposite were observed highest. The biocomposites fabricated with 72 h of treatment exhibited 16.8 % improvement in tensile modulus and 22.8 % increment in flexural modulus as compared to untreated fiber biocomposites. Furthermore, the highest levels of water absorption and impact strength were achieved through treatment duration of 96 h and 48 h, resulting in significant improvements of 63.2 % and 22.2 %, respectively. The assessment of surface characteristics was carried out through the use of optical microscopy and scanning electron microscopy (SEM).

Comparative Study between Radiofrequency Ablation and Laser Ablation in Treatment of Varicose Vein

Abstract Background Varicose veins are avery common problem all over the world. Surgery has been the gold standard treatment for many years, however now other less invasive options are available and sometimes more efficient. Aim of the Work The purpose of this study was to evaluate the RFA technique in treatment of GSV varicosities and to compare the results, clinical outcome, complications and recurrence rate after RFA and CS of GSV. Patients and Methods In this study 25 patients with varicose vein were randomized to laser ablation of GSV and another 25 patients underwent RFA of the GSV in Nasser institute. Both techniques were done under local (tumescent) anesthesia helped by sedation (Deprivan) in some patients or spinal anethesia in the other patients. Operative time was nearly the same in both techniques. no statistically significant difference between both techniques Results This study proved that radiofrequency and laser ablation techniques are safe and efficient in treating varicose veins and there was no statistically significant difference between both groups regarding postoperative complications or recanalization and recurrence. Conclusion Duplex guided radiofrequency ablation and laser ablation are efficient and safe modalities in the treatment of great saphenous vein varicosities. Conventional surgery has been used for a long time for treatment of varicose veins with variable degrees of minor to major complications. R radiofrequency and laser ablation of GSV in treatment of varicose vein provides high ablation rates in conjunction with a very moderate side effect profile