Treatment Of Senile Patients Research Articles

Analysis of Application Effect of Psychiatric Rehabilitation Training and Nursing in Rehabilitation Treatment of Senile Patients with Mental Diseases

Analysis of Application Effect of Psychiatric Rehabilitation Training and Nursing in Rehabilitation Treatment of Senile Patients with Mental Diseases

Clinical Value of Prosthodontics in the Treatment of Senile Patients with Oral Diseases

Clinical Value of Prosthodontics in the Treatment of Senile Patients with Oral Diseases

Clinical Effectiveness of Decitabine Combined with Reduced FLAG Regimen in the Treatment of Senile Patients with High-Risk Acute Myeloid Leukemia

To explore the efficacy and adverse reactions of decitabine combined with reduction FLAG regimen on the senile patients with high-risk AML. 12 senile patients with high-risk AML received decitabine combined with reduced FLAG regimen (decitabine 20 mg/m2, intravenous drip, qd, d 1-5; fludarabine 30 mg/m2, intravenous drip lasts 30 min, qd, d 3-6; Ara-C 1 g/m2, intravenous drip, qd, d 3-6; and G-CSF 300 μg/d, subcu- taneous injection, d 2 to neutrophils reached the lowest return to＞1.0×109/L) in our study. The efficacy and adverse reactions of this regimen were analyzed. 9 patients achieved complete remission(CR) after one course of decitabine combined with reduced FLAG regimen, 2 patients achieved partial remission (PR) and 1 patient reached a stable disease (SD). The overall response rate was 92%. The median follow-up period was 7.4 months ranged from 3 to 12 months. The median survival time for all patients was 6.4 months. The main treatment-related toxicities were myelosuppression and infection due to neutropenia. Severe non-hematologic toxicities were not observed in these patients, and there was no treatment-related mortality. Decitabine combined with reduced FLAG regimen has a definite clinical efficacy in the treatment of senile patients with high-risk AML. This regimen, as induction remission regimen, can effectively improve the CR rate and reduce the adverse reactions. Therefore, it may be used as one of the preferred induction remission regimen to treat the senile patients with high-risk AML.

Clinical observation of radiofrequency thermocoagulation combined steroid injection in treatment of the aged cervical spondylotic radiculopathy

Objective In this study, ultrasound and CT-guided radiofrequency ablation combined with injection through the cervical intervertebral foramen in the treatment of geriatric patients with cervical spondylotic radiculopathy (CSR) and just injection in the treatment of geriatric patients with CSR, compared the clinical effects of two different treatments on senile patients with CSR. Methods Forty geriatric patients with CSR were randomly divided into two groups using a random number table (n=20) : The test group (group T), The control group (group C). The course of treatment are under ultrasound for body surface location. Patients in Group T were treated with radiofrequency thermocoagulation (55 ℃ 60 s, 60 ℃ 120 s, 65 ℃ 60 s)+injection antiphlogistic and analgesic (prescription: 0.25% lidocaine+ 10 mg dexamethasone+ iohexol, a total of 4 ml). Patients in Group C were only treated with anti-inflammatory analgesic (prescription: 0.25% lidocaine+ 10 mg dexamethasone+ sterile saline, a total of 4 ml). The effectiveness evaluation mainly used the VAS score before treatment, 1 month after the treatment and 6 months after treatment to evaluate the clinical efficacy at 6 months after the treatment and the patients' satisfaction. Results All patients were treated successfully. During the process of treatment and after treatment, no patient showed vascular and nerve injury. Also, no patient had numbness and neurological dysfunction after operation. Pain VAS scores of group T and group C were lower than the values of before, 1 month and 6 month after the treatment (P<0.05). Among them, pain VAS score of group T decreased more significantly. The excellent rate of group T was 85% but the rate of group C was only 45%. There was significant difference between two groups (P<0.05). Conclusions Ultrasound and CT-guided radiofrequency thermocoagulation combined with injection through the cervical intervertebral foramen in the treatment of senile patients with CSR is a simple, safe and effective treatment method. Key words: Ultrasound; Radio frequency; Aged; Cervical spondylotic radiculopathy

Efficacy and safety of RevoLix 2 micron continuous wave laser vaporesection in treatment for senile patients with benign prostatic hyperplasia

The clinical efficacy and safety of RevoLix 2 μm continuous wave laser vaporesection in treatment of senile patients with benign prostatic hyperplasia (BPH) were retrospective evaluated. In 291 senile patients with BPH, 213 received 2 μm continuous wave laser vaporesection (group A) and other 78 patients received transurethral resection of prostate (TURP, group B). Compared with group B the intraoperative blood loss was less, the bladder irrigation time, catheter time and hospitalization time were shorter in group A. The subjective or objective indexes were all significantly improved at 3 and 12 months after laser treatment. The improvements of international prostate symptom score (IPSS), IPSS-S, overactive bladder symptom score (OABSS) in patients of 70-79 were more marked than those of 80 or older. Patients with mild overactive bladder (OAB) had less improvement in IPSS and IPSS-S than those with moderate-severe OAB which suggest that the storage symptoms could be improved significantly by removing obstruction. Key words: Lasers therapy; Prostatic hyperplasia; Transurethral resection of prostate

Analysis of failure after treatment of senile femoral intertrochanteric fractures with InterTan nails

Objective To analyze the causes for failed treatment of senile patients with femoral intertrochanteric fracture by the InterTan nailing system.Methods We retrospectively analyzed the clinical data of 337 elderly patients who had been treated in our department from April 2009 to December 2012 for femoral intertrochanteric fracture with closed reduction and internal fixation with InterTan nails.They were 189 males and 148 females,60 to 87 years of age (mean,69.7 years).According to the AO/OTA classification,71 fractures were type A1.1,89 type A1.2,78 type A1.3,51 type A2.1,35 type A2.2,7 type A2.3,and 6 type A3.We observed intraoperative and postoperative complications to analyze the causes for failed internal fixation and their preventive countermeasures.Results Of all the patients,205 were followed up for an average of 2.3 years (from 0.5 to 4.0 years).The rate of follow-up was 60.8％ (205/337).The fracture healed in 169 out of 205 patients after 2.6 to 3.4 months (average,2.9 months).Twelve months after operation,14 patients died and fixation failure occurred in another 22 patients (10.7％).Varus deformity was found 3 months postoperatively in 6 cases,of which 4 were complicated with cutout of a lag screw.At 6 months postoperatively,shortening of the femoral neck was found in 2 cases and varus deformity in 11 cases.After the intertrochanteric fracture healed during follow-up,3 cases of femoral fractures occurred at the end of the nail.We performed revision surgery for all these 22 cases of failed fixation.Arthroplasty was done for 5 cases and fixation was changed for 17 cases.After the revision surgery,fracture healed in 12 cases and 5 cases died within 12 months postoperatively.Conclusions The senile femoral intertrochanteric fractures can be successfully treated by the InterTan nailing system,but intraoperative and postoperative complications are inevitable.Good intraoperative manipulation is the key to preventing failure of the fixation and intensive postoperative follow-up is needed to watch out for complications like varus deformity,shortening of the femoral neck and cutout of a lag screw. Key words: Hip fractures; Fracture fixation, intramedullary; Bone nails; Old

Functional and Psychoemotional Rehabilitation of Senile Patients with Proximal Femus Fracture after Bipolar Hip Hemiarthroplasty

Ten years experience in treatment of senile patients with proximal femur fractures after hemiarthroplasty is presented. Data of clinical-functional and psychoemotional analysis show the efficacy of bipolar monoimplants application. Due to relatively high price bipolar hemiimplants are not widely used in native clinical practice however simplicity and low invasiveness of the intervention as well as good outcomes allow the authors to recommend more wide used of these implants.

The teriparatide in the treatment of severe senile osteoporosis

The osteoporosis is a systemic disease of multicausal etiopathogenesis. A progressive bone loss and qualitative alterations in the macro- and micro-architecture of the remaining bones, resulting in a loss of strength of bones to such an extent that even very modest traumas will cause fractures characterize it. Three forms are defined (i) postmenopausal appearing after the menopause, (ii) senile appearing with advancing age, and (iii) the idiopathic forms. Severe osteoporosis is declared when the patients suffer vertebral or femoral fractures without any trauma during a treatment with anti-reabsorptive medicines of at least 1-year. The treatment of osteoporosis is based on various categories of pharmaca, such as bisphosphonates, selective estrogen receptor modulators (SERMs), diaminobutyric acid (DABA), parathyroid hormone (PTH), estrogens and non-hormonal drugs. The teriparatide, the recombinant human (rh)PTH(1–34), is identical in amino acid sequence until the 34th (N-terminal) amino acid of the endogenous, human PTH. It is produced in E. coli using the recombinant DNA technology. It is a pharmacon having a strong trophic-anabolic action on the bone tissue, assuring both the inhibition of the bone loss, and the formation of new bones of good quality. It acts as a stimulant of the osteoblast functions, and at the same time, increases the absorption of calcium from the intestine, and also the renal reabsorption of calcium, and decreases the excretion of phosphates in the kidney. This study summarizes our own experience with the use of rhPTH(1–34) in the treatment of senile patients with severe osteoporosis. Our sample consisted of 40 elderly women of the mean age of 78 ± 5 years, having severe osteoporosis. They displayed a columnar T-score > −3.5 and femoral T-score > −2.5, had been under antireabsorptive treatment since at least 12 months. In particular, 15 patients were treated with Alendronate (70 mg/week), 10 of them with Risedronate (35 mg/week), and 15 of them with Raloxifene (60 mg/day). These patients in our study were treated for 1 year with 20 μg/day of rhPTH (1–34), injected subcutaneously, and supplemented also with a daily dose of 1 g of calcium and 800 IU of Vitamin D, per os. At start of this treatment (time t 0), after 6 months (time t 6) and after 12 months (time t 12) patients underwent a bone mineral density (BMD) analysis (Dexa-Lunar-DPX-P) on the lumbar vertebral column, (L1-L4 zone), as well as a femoral BMD. We applied also quality of life (QoL) questionnaire of the European Foundation for Osteoporosis (QUALEFFO), and evaluated also the use of non-steroidal anti-inflammatory drugs (NSAIDs). Our final considerations are that the teriparatide therapy increases significantly the bone mass density, expressed in terms of T-Score, reduces the occurrence of new fractures, improves the QoL, and decreases also the consumption of NSAIDs.

Colonoscopic screening and follow-up for colorectal cancer in the elderly.

To improve the prevention and treatment of senile patients with colorectal cancer by evaluating the importance of colonoscopy in clinical screening and follow-up. Clinical screening of colonoscopy was performed for 2196 patients aged 60-90 years old according to the protocol,and 1740 of them (79.2%) were followed-up. Colorectal cancer was found in 52 patients, and the detectable rate was 2.4%. Among them, 19 were diagnosed as early colorectal cancer, accounting for 36.5% of the detected colorectal cancer. Among the followed-up patients, early colorectal cancer was found in 9, accounting for 45.0% of the detected colorectal cancer. The resectable rate and 5 years survival rate of colorectal cancer were 97.7% and 80.9% respectively. The incidence of complication was 0.05%, and the successful rate of cecum intubation was 98.9%. Colonoscopic screening and follow-up of the elderly for colorectal cancer and pre-cancerous lesion (adenomatoid polyp) can increase the detectable rate of early colorectal cancer and improve its prevention and treatment.

Diagnosis and Treatment of Senile Patients with Consciousness Disturbance

Diagnosis and Treatment of Senile Patients with Consciousness Disturbance