Treatment Of Pyogenic Infections Research Articles

Changing pattern of antimicrobial resistance in clinical isolates from pyogenic infections in tertiary care hospital at Western Rajasthan, India

Background: Pyogenic wound infections are one of the most common clinical entities caused and aggravated by the invasion of pathogenic organisms. Despite the advancements in diagnostic techniques, treatment of pyogenic infections in the developing countries is challenging due to the emergence of multidrug-resistant (MDR) pathogens. This study was done to know the changing pattern of antimicrobial resistance in clinical isolates from pyogenic infections in patients attending a tertiary care hospital at Western Rajasthan, India. Methods and materials: This cross-sectional study was conducted at the Department of Microbiology in a tertiary care hospital during 2014–2015. Clinical specimens such as pus, wound aspirate, sterile body fluids except for CSF, wound swab, necrotic tissue, and surgical drainage were collected aseptically from suspected patients with pyogenic wound infections and processed. Bacterial isolates were identified by standard bacteriological methods and antibiotic susceptibility testing was done by Kirby-Bauer disc diffusion method as per CLSI guidelines. Results: Out of the total of 1190 clinical specimens processed, 231 (19.41%) specimens were from pyogenic infections; 108 (46.75%) specimens were culture positive. Gram-negative pathogens were 34%, followed by gram-positive pathogens which were 23%. Eleven percent were skin commensal flora. S. aureus (23%), E. coli (14%), Klebsiella spp. (7.4%), and Pseudomonas spp. (9.2%) were the common pathogens isolated. Staphylococcus aureus was resistant to Penicillin-G (100%), Erythromycin (56%) followed by Ciprofloxacin (28%). Among Enterobacteriaceae, Escherichia coli and Klebsiella spp. were resistant to Ampicillin (93.75%). and Amoxy-clave (93.75%) followed by ceftriaxone (81.25%). The majority of Pseudomonas isolates were susceptible to most of the antimicrobials. Conclusion: S.aureus and members of enterobacteriaceae are developing more resistance against commonly used antimicrobials, in comparison to Pseudomonas, which is commonly considered as a most resistant pathogen. This changing pattern is important in making the antibiotic policy.

Osteoarticular tuberculosis.

The radiological features of osteoarticular tuberculosis are quite variable. The rareness of AIDS-associated tuberculosis and relatively mild course and imaging features may be the common feature of osteoarticular tuberculosis in Japan. Imaging features are generally similar to other low-grade infections, and liberal (often incomplete) use of antibiotics for the treatment of pyogenic infection may also make the differential diagnosis difficult on many occasions.

Alfa-6-deoxy-oxy-tetracycline in the treatment of pyogenic infections of skin.

Alfa-6-deoxy-oxy-tetracycline in the treatment of pyogenic infections of skin.

Antibiotic treatment of pyogenic infections of dental origin

Antibiotic treatment of pyogenic infections of dental origin

Diagnosis and Treatment of Pyogenic Infections of the Intervertebral Disk

Diagnosis and Treatment of Pyogenic Infections of the Intervertebral Disk

Topical chloramphenicol (chloromycetin) therapy of pyogenic dermatoses.

The continuing search for more effective agents for the treatment of pyogenic infections of the skin has led to the development of many improved preparations over the past few years.1In the evaluation of a new agent, two basic factors must be observed. The agent must possess an active bacteriostatic effect, preferably in low concentrations, against a wide spectrum of microorganisms that commonly affect the skin. It must also show a low index of cutaneous sensitivity. Some of the newer antibiotic ointments appear to meet both of these criteria.1Another factor worthy of consideration is the stability of the preparation in various vehicles. This report evaluates topical chloramphenicol with reference to effectiveness in the treatment of pyodermas, to cutaneous allergenicity, and to applicability in a greaseless base. HISTORICAL DATA In 1947, Ehrlich and co-workers2announced the recovery of a new antibiotic, chloramphenicol (chloromycetin®), from Streptomyces venezuelae

Expectant treatment of pyogenic infections of the hand, with special reference to infection of the flexor aspect of the fingers.

Expectant treatment of pyogenic infections of the hand, with special reference to infection of the flexor aspect of the fingers.

Bacitracin in local treatment of pyogenic infections

Bacitracin in local treatment of pyogenic infections

Sterilization of blowfly eggs: In the culture of surgical maggots for use in the treatment of pyogenic infections

The separation and sterilization of blowfly eggs are significant factors in the culture of sterile maggots for use in the treatment of suppurative infections. Experiments were conducted on the separation of eggs and a method was devised by which they can be separated rapidly and without loss or injury. The method consists of briefly softening the egg clumps between layers of wet cloth and then separating them by spreading with a spatula. The technique involved in egg sterilization is described. Agglutination of eggs caused by certain disinfectants is discussed, and a means for its prevention given. Nine disinfecting combinations were tested on eggs in regard to sterility and mortality caused. A 5 per cent solution of formalin plus 1 per cent sodium hydroxide when used for five minutes was found to give the most satisfactory results from all viewpoints. Several solutions were tested against resistant spores and results showed the difficulty of finding disinfectants that would destroy the spores without greatly reducing the viability of the eggs. The age of eggs best adapted to sterilization varies with the disinfectant used. In contrast with several agents in common use, the one recommended in this article permitted a good hatch when used with freshly laid eggs. A suggested procedure for sterilizing eggs is given, which will permit disinfection the same day the eggs are laid, thereby reducing the time involved and lowering the cost of production.

The Treatment of Pyogenic Infection by Roentgen Irradiation

IT seems to me that, in recent years, too much attention has been paid to the treatment of malignancy and its allied conditions, to the utter neglect of some phases of radiotherapy from which more satisfactory results may be obtained. Too many physicians believe that the word “radiotherapy” is synonymous with “cancer therapy,” and this belief is the fault of the roentgenologist who for the past seven or eight years has devoted all his time to urging cancer therapy by means of X-ray treatment. I have purposely selected pyogenic lesions as the subject to be discussed because of the lack of literature concerning them. We have access to no end of papers and discussions on the treatment of hopeless malignancy and on the treatment of various leukemias, but when we look for the more every-day conditions, such as boils and carbuncles, we find only a few writers mentioning them. I believe that, in the near future, we shall find the trend of the roentgenologists, in increasing numbers, toward the treatment of these...

RÔLE OF SURGERY IN THE TREATMENT OF PULMONARY SUPPURATION

The same general principles of the treatment of pyogenic infections elsewhere apply equally well to those conditions of the lung. These are essentially (1) drainage, (2) obliteration of infected cavities and (3) extirpation of chronically inflamed tissue. The differences between suppurations of the lung and suppurations elsewhere consist chiefly in differences in the structure of the lung as compared with that of other organs. In this connection the lung should be regarded as a multilocular structure opening into a tube that leads to the outside of the body. Natural drainage, therefore, is usually through this tube and is often effective, leading to a spontaneous recovery. In many other cases, however, because of the multilocular nature of the lung parenchyma, many small abscesses occur which do not connect adequately with the natural drainage tube, and the result is therefore one of unsatisfactory drainage. The walls of the bronchi and bronchioles often