Treatment Of Meningococcal Meningitis Research Articles

Treatment of meningococcic meningitis in children with a single intravenous dose of sodium sulfadiazine: Report of nine cases

Summary 1. Nine patients reported here have been treated with a single dose of sodium sulfadiazine intravenously with complete recovery. 2. The single large intravenous dose of sulfadiazine will maintain a sulfa level in the spinal fluid and blood adequately long for rapid recovery. 3. With the present method of treatment there is every indication that the present quarantine period of meningococcic meningitis is unnecessarily too long. 4. It is possible that less than 2 grains per pound of body weight will be adequate to give the same result. Further studies will be necessary to determine the minimum single dose of sulfadiazine sufficient for rapid recovery. 5. High sulfadiazine levels are shown to be well-tolerated if adequate alkalinization of the urine is maintained. Gilligan, and associates 12 and Flippin, Schwartz, and Domm 13 have previously proved the advantages of adjuvant alkali therapy. 6. Spinal fluid cultures were sterile twenty-four hours after a single large intravenous dose of sodium sulfadiazine, thereby lessening the chance for complications and sequelae.

Sulphonamides in the Treatment of Meningococcal Meningitis

Sulphonamides in the Treatment of Meningococcal Meningitis

The Treatment of Meningococcic Meningitis

The Treatment of Meningococcic Meningitis

Treatment of Meningococcal Meningitis with Penicillin

Treatment of Meningococcal Meningitis with Penicillin

Treatment of Meningococcal Meningitis

Treatment of Meningococcal Meningitis

Treatment of meningococcic meningitis and septicemia: Sulfadiazine, sulfanilamide, and serum therapy

Treatment of meningococcic meningitis and septicemia: Sulfadiazine, sulfanilamide, and serum therapy

Sulfadiazine and its sodium compound in treatment of meningococcic meningitis and meningococcemia

sulfadiazine and its sodium compound in treatment of meningococcic meningitis and meningococcemia

Sulfadiazine and its sodium compound in treatment of meningococcic meningitis and meningococcemia

sulfadiazine and its sodium compound in treatment of meningococcic meningitis and meningococcemia

MENINGOCOCCIC INFECTIONS; REPORT OF 43 CASES OF MENINGOCOCCIC MENINGITIS AND 8 CASES OF MENINGOCOCCEMIA

Excerpt Recent reports indicate that there has been a marked increase in the incidence of cerebrospinal fever in Great Britain since the outbreak of the present war and similar increases have been ...

Treatment of Meningococcal Meningitis

Treatment of Meningococcal Meningitis

Treatment of Meningococcal Meningitis

Treatment of Meningococcal Meningitis

CHRONIC MENINGOCOCCEMIA PROMPTLY CURED BY SULFANILAMIDE

Sulfanilamide has been shown to be effective in the treatment of meningococcic meningitis. 1 Meningitis associated with acute meningococcemia has responded favorably to the drug. 1b Acute meningococcemia without meningitis has subsided after the administration of this therapeutic agent. 2 While sufficient data are not available for a final evaluation of the efficacy of this compound, it seems likely that it constitutes a valuable addition to the therapeutic armamentarium against meningococcic infection. The 2 cases of meningococcemia which are being reported are of interest because (1) in neither was there a demonstrable focus of infection; (2) in both chronic meningococcic bacteremia existed; (3) sulfanilamide in conventional doses promptly terminated the infection, and (4) we have not encountered in the literature reports of the use of sulfanilamide for this type of infection. REPORT OF CASES Case1.—E. B., a 12 year old girl, walked into the Nashville General Hospital on Feb.

A New Form of Treatment of Meningococcic Meningitis

A New Form of Treatment of Meningococcic Meningitis