The research belongs to those studies in which a successful attempt was made to investigate the moral foundations of Lesya Ukrainka's life strategy. The epistolary heritage was chosen as the object, as it is a grateful material for the study of the author as a real person without the admixture of interpretations of the recipients. A similar study is on time also because Lesya Ukrainka's published letters without Soviet banknotes are involved. Anthropological literary studies has been chosen as the main literary approach. This vector of exploration was determined by the reasoning of the well-known forester L. Skupeyko, who noted that modern science needs research on the concept of the author's personality. The study of the state of development of the problem has shown that science has occasional concluding statements, but there is no intelligence that would be the basis for such a study. Working with epistolary required special objectivity. M. Kotsyubynska's warnings about such treatment of letters were identified as the basis and important for compliance. To outline the content of the concepts of "responsibility" and "vocation" was chosen the latest study E. Mulyachuk. Thus, in order to determine one's own mission - life strategy - it is extremely important to be aware of one's own self-determination, to be ready to resist everyday life, and to give preference to the interests of others. Lesia Ukrainka's epistolary legacy gives grounds to say that it is important for a writer to have the inner strength to overcome her own misfortune in order to realize her own life strategy. This will help to overcome the fear of living. In addition, the awareness of the professional vocation must be in harmony with life goals. According to Lesia Ukrainka, the professional mission should be realized through a number of specific actions: publishing translations, forming a library, etc. In the future, it is advisable to continue the study of epistolary heritage, as well as to study the life strategies of the main characters of the writer's works. In this way, we will approach the creation of the concept of the personality of Lesya Ukrainka's work.