Treatment Of Axillary Hyperhidrosis Research Articles

Long-Term Quantitative Benefits of Botulinum Toxin Type A in the Treatment of Axillary Hyperhidrosis

Long-Term Quantitative Benefits of Botulinum Toxin Type A in the Treatment of Axillary Hyperhidrosis

Multi-Injection Plate for Botulinum Toxin Application in the Treatment of Axillary Hyperhidrosis

Department of Dermatology, Hospital Clinic, University of Barcelona, Barcelona, Spain Address correspondence and reprint requests to: Ramon Grimalt, MD, Department of Dermatology, Hospital Clinic, C/Villarroel 170, 08036 Barcelona, Spain, or e-mail: [email protected]. R. Grimalt, MD, G.A. Moreno-Arias, MD, and J. Ferrando, MD have indicated no significant interest with commercial supporters.

Multi-Injection Plate for Botulinum Toxin Application in the Treatment of Axillary Hyperhidrosis

Multi-Injection Plate for Botulinum Toxin Application in the Treatment of Axillary Hyperhidrosis

Botulinum toxin injection is an effective treatment for axillary hyperhidrosis.

Botulinum toxin injection is an effective treatment for axillary hyperhidrosis.

Treatment of axillary hyperhidrosis: combination of the starch-iodine test with the tumescent liposuction technique.

To evaluate and permanently improve axillary hyperhidrosis. Excessive sweating of the axillae is a common problem for which patients frequently seek dermatologic advice and therapy. Many treatments, including aluminum chloride, topical and systemic anticholinergic agents, tranquilizers, iontophoresis, direct surgical excision, botulinum toxin injection, and thoracic sympathectomy, have been employed to control this problem. All have drawbacks of one sort or another. The starch-iodine technique for delineation of preoperative and postoperative axillary sweating is described in detail. A method of sweat gland removal utilizing tumescent liposuction is discussed. The combination of the starch-iodine technique and tumescent liposuction is safe and effective for therapy of axillary hyperhidrosis.

Axillary Hyperhidrosis Treatment by Simple Skin Excision and Undermining

The current literature of axillary hyperhidrosis is reviewed. Excision of the gland-containing skin of the axilla has been a mainstay in the treatment of axillary hyperhidrosis for many years. A retrospective study was performed using data accumulated from 56 consecutive patients who underwent a surgical procedure modified from that originally described by Hurley and Shelley. Excision of the hair-bearing portion of the axilla with undermining of the adjacent skin and simple closure was performed under local or general anesthesia. Ninety-two per cent of patients were satisfied with the results. Five patients wished to undergo a second procedure, either because they still had excessive perspiration or because they were unhappy with their scars. Complication rates were low and were compared with other series. Thus, the described procedure provides a simple, safe and effective modality for the treatment of axillary hyperhidrosis.

Axillary hyperhidrosis treatment by simple skin excision and undermining

Axillary hyperhidrosis treatment by simple skin excision and undermining

Botulinum A neurotoxin for axillary hyperhidrosis. No sweat Botox.

Axillary hyperhidrosis causes considerable emotional stress and is associated with extraordinary costs and limitations in clothing. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae. Botulinum A neurotoxin (Botox) has been shown to decrease sweating in normal skin and in palmar hyperhidrosis. The current study was undertaken to demonstrate the utility of using Botox in the treatment of axillary hyperhidrosis. Twelve patient with axillary hyperhidrosis underwent intradermal injection with 50 units of Botox in the axillary skin bilaterally. All patients enjoyed relatively complete anhidrosis of the axillary skin in periods ranging from 4 to 7 months. Repeat injections produced similar results. Botulinum A neurotoxin (Botox) is an elegant and simple treatment for axillary hyperhidrosis.

Science, technology and government: The United Kingdom

Primary axillary hyperhidrosis has limited noninvasive, effective, and well-tolerated treatment options.To evaluate the topical treatment of axillary hyperhidrosis with the novel anticholinergic sofpironium bromide.A phase II, multicenter, randomized, controlled, double-blinded study. Participants were randomized to 1 of 3 dosages or vehicle, with daily treatment for 42 days. Coprimary end points were the percentage of participants exhibiting ≥1-point improvement in the Hyperhidrosis Disease Severity Measure-Axillary (HDSM-Ax) score by logistic regression, and change in HDSM-Ax as a continuous measure by analysis of covariance. Pair-wise comparisons were 1-sided with α = 0.10.At the end of therapy, 70%, 79%, 76%, and 54% of participants in the 5%, 10%, 15%, and vehicle groups exhibited ≥1-point improvement in HDSM-Ax (P < .05). Least-square mean (SE) changes in HDSM-Ax were −2.02 (0.14), −2.09 (0.14), 2.10 (0.14), and −1.30 (0.14) (all P ≤ .0001). Most treatment-related adverse events were mild or moderate.Not powered to detect changes in gravimetric sweat production.Sofpironium bromide gel produced meaningful reductions in hyperhidrosis severity and had an acceptable safety profile.

Carbon dioxide laser treatment vs subcutaneous resection of axillary osmidrosis.

Axillary osmidrosis is a distressing disorder characterized by unpleasant odor, profuse sweating, and occasional staining of clothes that may handicap those affected both socially and in the work place. Various types of surgical procedures have been developed for the treatment of axillary hyperhidrosis and osmidrosis. Our purpose is to seek a more effective surgical procedure than preexisting various subcutaneous resection techniques for axillary osmidrosis. After single transverse incision in the center of one axilla, undermining was performed from the incision edges to make a wide subcutaneous tunnel and then apocrine glands and subcutaneous fats were vaporized with a CO2 laser. Subcutaneous resection technique was performed on the opposite axilla in the same patient. A total of 20 patients have been evaluated for 4 months to 1 year, with an average of 8 months. The results from commonly used surgical procedures can be improved upon by the use of the CO2 laser. The frequency of complications and the mean duration of suture removal were diminished on the laser-operated side. CO2 laser vaporization in osmidrosis produces significant patient-benefit during the postoperative course. We believe that this laser-assisted combined surgical procedure can be a viable option for the treatment of axillary hyperhidrosis and osmidrosis.

Surgical treatment of axillary osmidrosis.

Various types of surgical procedures have been developed for treatment of axillary hyperhidrosis and osmidrosis. However, Asian people tend to seek treatment for osmidrosis rather than hyperhidrosis. In this article, we report a new modified surgical method concerning axillary osmidrosis. At first we make four transverse parallel incisions; two incisions in the center are large (approximately 4 cm in length) and the lateral ones are small (approximately 1.5 cm in length). Then, we do enough undermining from the four wound edges to make a wide subcutaneous tunnel, and the adipose tissue beneath the skin is removed with scissors through each incision. Finally, two pieces of Penrose drain are inserted through the small lateral incisions. With this method we have operated on 21 patients in the past 3 years; 19 patients were female, and only 2 were male. Patients were followed for a minimum of 3 months and a maximum of 22 months, with an average follow-up of 7 months. In terms of results, 14 were good, 5 fair, and 2 poor. Minor complications such as partial epidermal necrosis occurred in only 2 patients, but healed with conservative treatment, and other complications such as hematoma formation or infection did not occur. In this article, we emphasize two merits of our procedure. One is that adding small incisions at both lateral margins makes it possible to perform the further excision of the apocrine glands. The other merit is that drainage from the small incisions is very effective. We believe this procedure is a viable option for treatment of axillary hyperhidrosis and osmidrosis.

A noninvasive surgical treatment of axillary hyperhidrosis

E xcessive inappropriate sweating is an acute problem for many individuals, both men and women. Patients troubled with this condition are usually emotionally sensitive and perspire profusely at a slight stimulus. The disorder first appears at puberty, on maturation of the apocrine glands. These patients find their lives deeply affected. They suffer the embarrassment and discomfort of stained clothing and odor. They may be barred from many occupations and social activities. Dermatitis and intertrigo may develop in the chronically damp axilla, even in patients of normal weight and body configuration.

Liposuction for Treatment of Axillary Hyperhidrosis

Axillary hyperhidrosis is a common and often troublesome problem. Current therapy includes topical antiperspirants, systemic anticholinergic medications, iontophoresis, and surgery. Axillary liposuction promises to be the surgical treatment of choice for those patients refractory to other modalities.

Prophylactic Antibiotics in Surgical Treatment of Axillary Hyperhidrosis

Prophylactic Antibiotics in Surgical Treatment of Axillary Hyperhidrosis

Surgical treatment of axillary hyperhidrosis.

In the human axilla, the proportion of eccrine and apocrine sweat glands is 1:1. The former are in the dermis, while most of the latter are in the subcutaneous cellular tissue. After studying the difficult methods that have been described for the surgical treatment of axillary hyperhidrosis, we concluded that the treatment should be as radical as possible and deal with both types of glands. The technique described here is a combined method which removes en bloc the skin and subcutaneous cellular tissue of more than half the area of sweating and the subcutaneous cellular tissue of the rest, leaving an S-shaped scar that follows the main axis of the axilla. Problems with this method have been minimal. Follow-up studies carried out up to 3 years after the operation have indicated excellent results.

Axillary hyperhidrosis: A simple surgical procedure.

A simple method for surgical treatment of excessive sweating of the axilla is presented. The procedure, which is performed under local anesthesia on an outpatient basis, is described in detail. After mapping the sweat gland bearing area with crepe paper, the hyperhidrotic area was excised using a bat-shaped excision. The skin was closed without undermining. This method has been used in 14 consecutive patients (28 axillae) resistant to topical administration of aluminum chloride hexahydrate in ethanol. The postoperative results were excellent in 12 patients and were good in 2. There were three minor wound infections and one case of postoperative bleeding. This procedure is suitable for all patients who need surgical treatment for axillary hyperhidrosis and requires no training in plastic surgery.

Axillary skin excision for the treatment of axillary hyperhidrosis

Axillary skin excision for the treatment of axillary hyperhidrosis

Treatment of axillary hyperhidrosis.

Treatment of axillary hyperhidrosis.

Treatment of axillary hyperhidrosis

Treatment of axillary hyperhidrosis

Points: Treatment of axillary hyperhidrosis

Points: Treatment of axillary hyperhidrosis