Insulin delivery through an insulin pump may help maintain blood glucose levels during exercise. Accordingly, individuals on insulin pump therapy may be able to better meet the current recommended guidelines for daily, moderate exercise in comparison to diabetics relying on injected insulin. Currently no data are available regarding the short-term effects of moderate-level exercise on blood glucose levels in IDDM patients undergoing initial insulin pump therapy. Therefore, the purpose of this study was to determine the change in blood glucose (BG) level following an exercise bout designed to meet the current recommendations outlined by the CDC and ACSM. Twenty-two patients (36± 15 yr) undergoing initial insulin pump therapy (basal rate: 0.4± 0.2 units/hr) participated in this study. Each exercise session consisted of approximately 5 min of warm-up, 20 min of conditioning, and 5 min of cool-down exercises for a total exercise time of approximately 30 min. Blood glucose samples were analyzed at rest and immediately after treadmill walking at a self-selected pace (2.8 ± 0.5 mph, 62±%MaxHR, 12± 1 RPE, and 3.3 ±.88 METs). Data were analyzed by the Student's T-test. Following exercise BG decreased (total change: 55 ± 36 mg/dL, pre-BG 180 ± 50, post-BG 125 ± 48; ρ<0.05). These results indicate that moderate-level treadmill walking in patients undergoing initial insulin pump therapy is a safe an effective means of controlling exercise BG. Further, better exercise BG control may help individuals with IDDM meet recommended daily requirements for physical activity.