The paper describes a discrete-event simulation model of transport and logistics infrastructure on the example of a road intersection at Profsoyuznaya Street, 64 k.2 / Nametkina Street, 6. The model allows the studying of traffic processes at the intersection with a high degree of accuracy, drawing analytical conclusions and making correct management decisions to improve the traffic situation on the basis of these conclusions. The developed simulation model consists of road network elements, agent generation system, process diagram functional blocks, control elements and infographics, etc. A number of simple experiments were performed with the model, including optimization, as a result of which the most optimal duration of the traffic light phases was determined, which ensures the minimum average travel time of vehicles. In addition, the model includes ground crossings that allow the study of the behavior of pedestrian masses when crossing the carriageway. The proposed solutions to the organization of traffic and pedestrian flows can be used to implement simulation models for a wide range of issues of modeling transport and logistics infrastructure, including railway transport, for example, when developing simulation models of transport interchange nodes. Software that was used in the study: the simulation environment AnyLogic 8 and the object-oriented programming language Java. The conducted research and preparation of the publication were carried out as part of the implementation of a grant from Russian Railways for the development of scientific and pedagogical schools in the field of railway transport.