This paper reports on an experimental study of influences of the bias direct currents on the transverse giant magnetoimpedance effect in a FeCoNiBSiMo microwire. Along with increasing the bias direct currents, the low field sensitivity of the impedance increases evidently at high frequency (10–120 MHz). The low field sensitivity (4 Oe) by presence of 30 mA of bias direct currents is about 3 times larger than that without using bias direct currents at 60 MHz. However, the high field sensitivity of the impedance decreases by use of bias direct currents at high frequency. In addition, the low field linearity is improved by use of bias direct currents at high frequency. The experimental results could be very useful for the design of multi-dimensional giant magnetoimpedance sensors with high low field sensitivity and linearity.