In 1930 and in 1934 Milkman1reported a case exhibiting a skeletal osteopathy which he considered unique and which he named spontaneous idiopathic symmetrical In the succeeding twelve years we were able to find references to only 3 similar cases2in the English literature and to 15 cases in the foreign medical literature. Our purpose in this report is to review briefly the literature and to add a twentieth case. This syndrome is characterized by pain, disturbances of gait and the radiologic appearance of multiple transparent bands or zones often symmetrically located in various portions of the skeleton, usually interpreted as representing fractures. Locomotion eventually becomes so impeded as to render the patient bedfast. REPORT OF CASE History.— Mrs. H. S., aged 34, a native American housewife, was admitted to Mount Sinai Hospital on July 16, 1942 complaining of weakness, painful lower extremities and inability to