Learning Objectives To review the prevalence, etiology, pathogenesis, anatomy, presentation, and diagnosis of ectopic varices. The variety of transcatheter approaches, techniques, technical tips, risks, and results of each will be presented. Background Ectopic varices may be best defined as large pressurized portosystemic venous collaterals occurring anywhere in the abdomen except in the gastro-esophageal region. They account for up to 5% of all variceal bleeding; however, hemorrhage can be massive with mortality reaching up to 40%. They can develop in sites of prior surgical adhesions or spontaneously through latent embryologic portosystemic anastomoses. Given their sporadic nature, literature is limited to case reports, small case series and reviews, without guidelines on management. Clinical Findings/Procedure Details This exhibit illustrates the pathways and clinical presentations of duodenal, jejunal, ileal, stomal, colonic, roux, gallbladder, rectal, urinary bladder, umbilical, and retroperitoneal varices, and their respective interventional therapies. The role of diagnostic CT, sonography, angiography, and venography is reviewed. The authors demonstrate in a pictorial fashion, drawing upon extensive experience as well as comprehensive lliterature review. Techniques include antegrade transjugular, transhepatic and transsplenic approaches with or without shunt creation; embolization, and variceal obliteration using coils, plugs, sclerosants, and adhesives; B-RTO approaches (through renal/adrenal/ gonadal approaches, etc); and direct variceal puncture by sonographic guidance. Tabular results from published literature are presented,with an algorithm for choosing therapeutic approaches for individual cases. Conclusion and/or Teaching Points Ectopic varices develop and present in a myriad of locations and fashions, from mild, occult, to massive intra or retro-peritoneal, urinary, or gastrointestinal hemorrhage. In 2012, the interventional radiologist has multiple, new demonstratedly effective means of providing temporizing or definitive therapy, warranting high suspicion, early diagnosis, referral and intervention.