Tool For Transfer Research Articles

Temporal Variations in Vertical Cloud Structure of Jupiter's Great Red Spot, Its Surroundings and Oval BA From HST/WFC3 Imaging

AbstractIn this study, we present the evolution of the properties and vertical distribution of the hazes in Jupiter's Great Red Spot (GRS), its surroundings and Oval BA from 2015 to 2021. To retrieve the main atmospheric parameters, we model the spectral reflectivity of a number of dynamically and/or spectrally interesting regions with a radiative transfer tool that uses an optimal estimator scheme. The spectra of the selected regions are obtained from high‐resolution Hubble Space Telescope Wide Field Camera 3 images that cover the spectral range from 200 to 900 nm. The a priori model atmosphere used to describe the various Jovian regions is taken from Anguiano‐Arteaga et al. (2021, https://doi.org/10.1029/2021JE006996) for each corresponding area. We find that the biggest variations in the GRS occur in the optical thickness of the stratospheric and tropospheric haze layers starting in 2019 and in the mean size of the tropospheric haze particles in 2018. The absorption spectra of both hazes show little variations among the analyzed regions and years, with the stratospheric haze properties seeming compatible with the chromophore proposed by Carlson et al. (2016, https://doi.org/10.1016/j.icarus.2016.03.008). We report a color change of Oval BA from red to white during these years that, according to our models, can be mostly explained in terms of a decrease in the stratospheric haze optical depth.

Improvement and applications of adeno-associated virus 2 (AAV-2) system for efficient gene transfer and expression in penaeid shrimp cells

Adeno-associated virus 2 (AAV-2)-mediated expression system is a well-developed and widely used gene transfer and expression tool in mammalian cells, but no attempt has been done to examine its infection and expression efficiency in shrimp cells. In this study, using eGFP as a reporter gene, we found that unmodified AAV-2 could infect primarily cultured shrimp hemolymph cells, but with an extremely low infection efficiency of up to 0.0067%. However, all the improvements of AAV-2 expression system tried in this study including the insertion of shrimp virus (IHHNV)-sourced P2 promoter into the AAV-2 vector (i.e. pAAV-CMV-P2-eGFP) and the inclusion of shrimp virus (IHHNV)-sourced nucleocapsid protein （IHCP） into or association of shrimp virus (WSSV)-sourced tegument protein (VP26) with the capsid of the improved AAV-2 s, respectively, could significantly increase the infection and expression efficiencies of this expression system in the primarily cultured shrimp hemolymph cells in comparison with wild-type AAV-2. Moreover, from the viewpoint of improving the infection and expression efficiency, the insertion of P2 promoter did best, followed by the association of WSSV tegument protein of VP26, and the last was the inclusion of IHHNV nucleocapsid protein of IHCP. In conclusion, an improved AAV-2 expression system which consists of four expression plasmids of pAAV-CMV-P2-eGFP, pAAV-RC, pHelper and pcDNA3.1-VP26 and one packaging cell line of HEK293T has been successfully developed in this study. This improved AAV-2 expression system will provide us a useful tool for efficient gene transfer and expression in shrimp cells.

Representative Survey for Evaluating Housing and Manure Handling Technologies of the Hungarian Pig Sector.

In Hungary, there is a lack of information on the pig production technologies in place in the base year of 2005 and changes since then, as well as a lack of information on the number of pigs kept in different age and production categories, which makes it difficult to calculate ammonia emissions and reductions in the national inventories. Our research team conducted a representative survey of pig farms to assess housing and manure management technologies in the Hungarian pig sector in 2005 and 2015. Novel expert-based calculation methods were developed to convert farm data on pig populations into daily average numbers (DAN) of animals in different statistical categories and feeding phases. The survey resulted in a representative database of housing, manure handling, storage and manure application practices in Hungarian pig production. The data and methodology from the survey helped to develop an ammonia emission calculator and knowledge transfer tool (AGEM-S) for use by farmers.

Examining the Use of Text Messages Among Multidisciplinary Care Teams to Reduce Avoidable Hospitalization of Nursing Home Residents with Dementia: Protocol for a Secondary Analysis.

Reducing avoidable nursing home (NH)-to-hospital transfers of residents with Alzheimer disease or a related dementia (ADRD) has become a national priority due to the physical and emotional toll it places on residents and the high costs to Medicare and Medicaid. Technologies supporting the use of clinical text messages (TMs) could improve communication among health care team members and have considerable impact on reducing avoidable NH-to-hospital transfers. Although text messaging is a widely accepted mechanism of communication, clinical models of care using TMs are sparsely reported in the literature, especially in NHs. Protocols for assessing technologies that integrate TMs into care delivery models would be beneficial for end users of these systems. Without evidence to support clinical models of care using TMs, users are left to design their own methods and protocols for their use, which can create wide variability and potentially increase disparities in resident outcomes. Our aim is to describe the protocol of a study designed to understand how members of the multidisciplinary team communicate using TMs and how salient and timely communication can be used to avert poor outcomes for NH residents with ADRD, including hospitalization. This project is a secondary analysis of data collected from a Centers for Medicare & Medicaid Services (CMS)-funded demonstration project designed to reduce avoidable hospitalizations for long-stay NH residents. We will use two data sources: (1) TMs exchanged among the multidisciplinary team across the 7-year CMS study period (August 2013-September 2020) and (2) an adapted acute care transfer tool completed by advanced practice registered nurses to document retrospective details about NH-to-hospital transfers. The study is guided by an age-friendly model of care called the 4Ms (What Matters, Medications, Mentation, and Mobility) framework. We will use natural language processing, statistical methods, and social network analysis to generate a new ontology and to compare communication patterns found in TMs occurring around the time NH-to-hospital transfer decisions were made about residents with and without ADRD. After accounting for inclusion and exclusion criteria, we will analyze over 30,000 TMs pertaining to over 3600 NH-to-hospital transfers. Development of the 4M ontology is in progress, and the 3-year project is expected to run until mid-2025. To our knowledge, this project will be the first to explore the content of TMs exchanged among a multidisciplinary team of care providers as they make decisions about NH-to-hospital resident transfers. Understanding how the presence of evidence-based elements of high-quality care relate to avoidable hospitalizations among NH residents with ADRD will generate knowledge regarding the future scalability of behavioral interventions. Without this knowledge, NHs will continue to rely on ineffective and outdated communication methods that fail to account for evidence-based elements of age-friendly care. DERR1-10.2196/50231.

From colonial celebration to postcolonial performativity: ‘guilty multilingualism’ and ‘performative agency’ in the English Medium Instruction (EMI) context

ABSTRACT This article reports data from a qualitative study conducted within the elitist English-medium schools in three cities of Pakistan to claim that theory building, and English teaching practices are still modeled on monolingual biases inherent in the orthodox notions of linguistic purism and Anglo-normative traditions of the 1990s. Orthodoxy is manifest in schools’ strong emphasis on direct method and communicative language teaching, and essentialist language management where English is enforced as the sole legitimate language of academic and non-academic transactions. Native language use is attached a stigma and viewed as deficiency in the English language. Such Anglo-normative culture invokes guilty conscience in teachers and students as they disapprove native languages even when they know that they can serve as useful meditating tools for effective content transfer. Crucially, amid English gatekeepers’ celebratory attitudes toward English as the sole legitimate language, some teachers still demonstrate deviation from the pervasive linguistic norms. Showing reflexivity and agency, these teachers ideologically oppose the official policy. They discursively generate spaces for negotiating and appropriating the official policies, which signifies that language policy can be a complex multi-layered process rather than a linear, discrete, or top-down phenomenon. Teachers’ agency is interpreted as ‘decolonial performativity’.

Cell Surface Labeling and Detection of Protein Tyrosine Kinase 7 via Covalent Aptamers.

Covalent aptamers are novel biochemical tools for fast and selective transfer of labels to target proteins. Equipped with cleavable electrophiles, these nucleic acid probes enable the installation of functional handles onto native proteins. The high affinity and specificity with which aptamers bind their selected targets allows for quick, covalent labeling that can compete with nuclease-mediated degradation. Here, we introduce the first application of covalent aptamers to modify a specific cell surface protein through proximity-driven label transfer. We targeted protein tyrosine kinase 7 (PTK7), a prominent cancer marker, and demonstrated aptamer-mediated biotin transfer to specific lysine residues on the extracellular domain of the protein. This allowed for tracking of PTK7 expression, localization, and cellular internalization. These studies validate the programmability of covalent aptamers and highlight their applicability in a cellular context, including protein and small molecule delivery.

3DLightBeam+. Design, simulation, and testing of carbon-efficient reinforced 3D concrete printed beams

The paper presents a workflow for the design, material testing and numerical simulation of shape-optimised reinforced 3D Concrete Printed (3DCP) beams tested structurally in three-point bending. Building upon previous research on structurally optimised toolpath planning for 3DCP, the presented work suggests a method for the computational design optimisation process based on material efficiency principles and the parallel development of a lossless data transfer tool from the 3D modelling environment to a Finite Element Analysis (FEA) workspace taking into account the layered process characteristic of 3DCP and the consequent weak interactions generated between adjacent printed concrete filaments. The proposed FEA model was calibrated through cored cylindrical specimens and then applied to the design, fabrication and experimental testing of a proof-of-concept shape- and infill-optimised 3-metre simply supported beam. The comparative analysis of simulation and structural testing proves the reliability of the numerical model, which correctly estimated peak load and damage patterns for 3DCP. The tests highlight how, with a shear failure mode, the dominant cracks start from the support region and reach the area of load application. The presented work advances the research in 3DCP by developing 3DLightBeam+, a carbon-efficient reinforced concrete beam design with a 200% higher flexural strength-to-weight ratio than a full comparable beam. The beam is conceived through a seamless workflow for its FE analysis and structural verification that accurately predicts structural capacity and behaviour without destructive testing methods.

CRBF: Cross-Referencing Bloom-Filter-Based Data Integrity Verification Framework for Object-Based Big Data Transfer Systems

Various components are involved in the end-to-end path of data transfer. Protecting data integrity from failures in these intermediate components is a key feature of big data transfer tools. Although most of these components provide some degree of data integrity, they are either too expensive or inefficient in recovering corrupted data. This problem highlights the need for application-level end-to-end integrity verification during data transfer. However, the computational, memory, and storage overhead of big data transfer tools can be a significant bottleneck for ensuring data integrity due to the large size of the data. This paper proposes a novel framework for data integrity verification in big data transfer systems using a cross-referencing Bloom filter. This framework has three advantages over state-of-the-art data integrity techniques: lower computation and memory overhead and zero false-positive errors for a limited number of elements. This study evaluates the computation, memory, recovery time, and false-positive overhead for the proposed framework and compares them with state-of-the-art solutions. The evaluation results indicate that the proposed framework is efficient in detecting and recovering from integrity errors while eliminating false positives in the Bloom filter data structure. In addition, we observe negligible computation, memory, and recovery overheads for all workloads.

Assessment of the Apical Transportation and Quantity of Root Canal Dentin Removed Using Different New Rotary File Systems: An Original Study.

The rotary systems have found a common application in the clinical practice for the endodontic therapies. Hence, we compared three recent endodontic systems for the comparison of the dentine removal and the apical transportation particularly in the curved canals. Oneshape, Pro Taper Next, and Edgefile X3 were the three systems that were compared. Thirty maxillary mesio buccal canals of the human permanent teeth were compared due to its curved nature. The volume of dentin removed and apical transportation (mm) were measured using micro-computed tomographic imaging (mm). Both the coronal section and the entire canal length had their dentin removed in accordance with measurements. Total dentine removed, coronal dentine removed, and the canal transportations were compared for the three rotary file systems. The values were compared with appropriate statistical tests for evaluating the significance. There was no statistically significant difference between the three file systems for the dentin removed. The mean canal transportation was 0.33 ± 0.12, 0.21 ± 0.25, and 0.23 ± 0.21 mm, respectively, for Oneshape, Pro Taper Next, and Typhoon CM. In terms of statistics, there were no appreciable variations among the three rotary tools for apical transfer. The three rotary systems were comparable for the apical transportation and the dentine removal. Despite variations in the magnitude of apical enlargements, none of the instrumentation methods detected apical transportation.

Physical conditions for dust grain alignment in Class 0 protostellar cores

Context. The polarized dust emission observed in Class 0 protostellar cores at high angular resolution with ALMA has raised several concerns about the grain alignment conditions in these regions. Aims. We aim to study the role of the radiation field in grain alignment mechanisms that occur in the interior (≤1000 au) of Class 0 protostars. Methods. We produced synthetic observations of the polarized dust emission from a magnetohydrodynamic model of protostellar formation using the POLARIS dust radiative transfer tool, which includes dust alignment with radiative torque alignment (RAT). We tested how the polarized dust emission from the model core depends on the irradiation conditions in the protostellar envelope by varying the radiation due to accretion luminosity propagating from the central protostellar embryo throughout the envelope. The level of grain alignment efficiency obtained in the radiative transfer models was then compared to (sub)millimeter ALMA dust polarization observations of Class 0 protostars. Results. Our radiative transfer calculations have a central irradiation that reproduces the protostellar luminosities typically observed toward low- to intermediate-mass protostars, as well as super-paramagnetic grains and grains ≥10 µm, which are required to bring the dust grain alignment efficiencies of the synthetic observations up to the observed levels. We discuss the characteristics timescales of the grain alignment physics together with the radiative torque disruption (RATD) of grains and the typical time variability of accretion occurring in Class 0 protostellar cores. In our model, during an accretion burst or a steady-state phase of high luminosity from the protostellar embryo, RATD could have enough time to disrupt the largest grains in irradiated regions. Finally, in high-luminosity conditions (with L★ ≥ 20 L⊙ in our model), we find that the alignment of grains with respect to the anisotropic component of the radiation field (k-RAT) could drive inefficient alignment for grains ≳10 µm. However, given the high grain alignment efficiency observed in protostellar envelopes, large grains are most likely aligned with the magnetic field and thus potentially subject to rotational disruption, depending on their tensile strength. Conclusions. Our radiative transfer calculations show that irradiation plays an important role in the mechanisms that dictate the size range of aligned grains in Class 0 protostars. Regions of the envelope that are preferentially irradiated harbor strong polarized dust emission but can be affected by the rotational disruption of dust grains, thus controlling the population of the largest aligned grains. Episodes of high luminosity could affect grain alignment and trigger grain disruption mechanisms.

Tools for care transfer in intensive care units: systematic review of observational studies

Objective: to evaluate the effectiveness of the use of tools for care transfer in patients admitted to an intensive care unit (ICU). Methods: Systematic review consulted in the databases PubMed, Embase, Cochrane Library, LILACS until August 2022. The descriptors “Patient Handoff”, “Continuity of Patient Care”, “SBAR”, “ISBAR”, “SBAR-R”, “ISBARR”, “ISOBAR”, “Communication” and “Intensive Care Units” were used. Observational studies use of any tools to transfer care in patients admitted to any ICU were included. Risk of bias using the Newcastle-Ottawa Scale. Results: the findings suggest that the professionals' perceptions are positive and that there was an improvement in multidisciplinary communication. As for the impact on patient care, the findings suggest that the use of transfer tools in care favors the complete completion of the medical record, as well as the notification of events in the medical records. Conclusions: no robust evidence was found regarding the use of ICU care transfer tools.

Gene therapy for inborn errors of immunity.

In the early 1990's, gene therapy (GT) entered the clinical arena as an alternative to hematopoietic stem cell transplantation (HSCT) for those forms of inborn errors of immunity (IEIs) that, because of their severity, are not medically manageable. In principle, the use gene-corrected autologous hematopoietic stem cells presents several advantages over HSCT, including making donor searches unnecessary and avoiding the risks of graft-versus-host disease (GVHD). In the past 30+ years of clinical experience, the field has witnessed multiple examples of successful applications of GT to a number of IEIs, as well as some serious drawbacks that have highlighted the potential genotoxicity of integrating viral vectors and stimulated important progress in the development of safer gene transfer tools. The advent of gene editing technologies promises to expand the spectrum of IEIs amenable to GT to conditions caused by mutated genes that require precise regulation of expression or by dominant-negative variants. Here, we review the main concepts of GT as it applies to IEIs and the clinical results obtained to date. We also describe the challenges faced by this branch of medicine that operates in the unprofitable sector of human rare diseases.

DESIGN OF A 10 TONS OVERHEAD CRANE WITH 21 METERS SPAN USING FINITE ELEMENT METHOD

A crane is a lifting equipment widely used to move cargo, construction sites, storage, and unload. The type of crane that is commonly used in industrial environments is the overhead crane. The overhead crane functions as a lifting device. Besides that, it also works as a load transfer tool even though the load being moved is limited to an environment that is not too large (indoor) at PT. A overhead crane is designed to overcome the problem of moving material in the mold storage area due to the area's expansion and the addition of 5-7 tons of mold material. Therefore, proper design is needed so the overhead crane can function properly. The design method uses the VDI 2221 or Finite Element with Solid works software. The results of the structure obtained are double box girder type girders with dimensions p = 21 m, t = 1224 mm, and l = 600 mm. The deflection results are 13.75 mm, and the runway uses steel profile I with dimensions 400 x 200 x 8 x 13 mm, with a deflection value at the runway stem of 5.6 mm. The type of wire rope used is type 6 x 37, with a diameter of 28 mm. The stress that occurs in the steel rope is 4306.1 Kg, less than the maximum allowable tensile stress of 8009.4 Kg. The single hook type with a hook diameter of 120 mm is made of material S45C. The tensile stress on the hook is 0.88 Kg, and the result is smaller than the allowable tensile stress of 12.72 Kg. The pulley diameter is 630 mm, the drum diameter is 604.9 mm, and the drum length is 279 mm.

The Regulation of Foreign Workers as Technology and Knowledge Transfer

The regulation of using foreign employees as a tool for technology and knowledge transfer, roadblocks that arise while implementing technology and knowledge transfer, and government initiatives to promote the quickening of technology and knowledge transfer are all examined in this study. This study is a normative legal investigation. Legal main and secondary sources are examples of primary data. The method for gathering data was a literature review, which involved reading books, looking over rules and regulations, and looking over other relevant research findings. The findings of this study suggest that Indonesia's laws governing the employment of foreign workers have not explicitly restricted the means through which technology can be transferred through foreign workers.

RANCANG BANGUN SISTEM KONTROL MINIATUR ALAT PEMINDAH MATERIAL PADA PROSES DISTRIBUSI BIJIH NIKEL MENGGUNAKAN PLC

This research aims to make a miniature ore material transfer tool automatically using Omron PLC. The way this tool works is that when the start button is pressed, motor 1 will move the apron containing the ore to be taken to the 3 storage barrels to be filled alternately. In each storage barrel, a proximity sensor is installed to detect the level of ore filling. On the rails that are passed by the apron, there are three limit switches that serve as indicators that the position of the apron is right above the storage barrel, then motor 2 will open the valve on the apron so that the ore on the apron falls into the reservoir. From this research, we have succeeded in obtaining an automatic control system for a miniature material transfer device in the ore distribution process.

Integrated modeling of cracking during deep penetration laser welding of nickel alloys

During deep penetration laser welding of nickel alloys, interactions between composition and processing conditions can lead to the formation of defects. Inconel 740H, for example, has demonstrated a susceptibility to horizontal fusion zone cracking at locations between 70% and 80% of the weld depth during laser welding at powers above 5 kW. Coupling three-dimensional heat transfer, fluid flow, and stress modeling tools allowed that both the strain rate and stress normal to the solidification direction to be calculated. In the Inconel 740H welds, cracks formed at locations where the strain rate and stress simultaneously reached critical levels. No cracking was observed in the Inconel 690 welds, since the strain rate and stress did not simultaneously reach these critical levels.

'Schrems II' Judgment C-311/18: Application of Charter Rights to Data Protection and Effective Remedy Beyond Eu Borders - A State of Play and a Critical Reflection Two Years Later

In its Schrems II judgment,1 the Grand Chamber of the Court ruled that the United States law and practices, notably bulk-interception programmes, were not providing a level of protection of personal data essentially equivalent to the protection conferred by the EU Charter of Fundamental Rights and, therefore, invalidated the Privacy Shield for violating Articles 7 and 8 of the Charter. Since, in addition, there is no effective remedy available to data subjects protected by the GDPR, the Court held that the Privacy Shield also violated Article 47 of the Charter. The Court, nevertheless, left the standard data protection clauses as one of the transfer tools available to data exporters, with the understanding that it is up to the data exporter to implement the additional safeguards necessary to compensate for any shortcomings in the third country and achieve an essentially equivalent level of protection. While the judgment provides, to some extent, clear guidance on the application of EU law and maps out a coherent regime as to how data can be transferred, this article reflects on some aspects that remain problematic in practice, both for data exporters in general and for the original complainant in the Schrems litigation in particular.2The 'risk-based approach' and its recognition are discussed, revealing that ultimately the law, and the Court's judgment, do not seem to allow for certainty in this matter and require the stakeholders to take a position in their respective situations, choosing between a strict or stretched interpretation.

WhatsApp Messenger as a Supplementary Tool for School Curriculum Knowledge Transfer and Acquisition During COVID-19 Stricter Lockdown: Educators’ Perceptions

The COVID-19 pandemic was unarguably one of the most disastrous events whose detriment to the normalcy of the education and training sectors will never be forgotten. To salvage the academic year, the Department of Basic Education (DBE) encouraged historically disadvantaged schools to explore rotational learning supplemented by mobile learning (with WhatsApp Messenger as schools’ most preferred application). However, in face of the concerns that were raised by the media, educational commentators, student bodies and teacher unions about the lack of public schools’ readiness for mobile learning, this social constructivist oriented qualitative study (which drew on 12 educators’ diverse and convergent views) adopted a Technology Acceptance Model (TAM) as a lens to investigate educators’ perceptions of WhatsApp messenger as a supplementary mode of curriculum knowledge transfer and acquisition during COVID 19 stricter lockdown at three historically disadvantaged schools in South Africa. Participants generally deposited positive feedback regarding the benefit of using it WhatsApp messenger to engender curriculum knowledge transfer and acquisition. They however explicitly also detailed a few negative aspects of this pursuit, primarily on how for socio-economic related reasons, the process was not completely inclusive as some learners could not partake in it. Also, educators admitted that while going beyond the call of duty was necessary during the pandemic, WhatsApp mediated teaching consumed most of their leisure time. According to them, this was compounded by poor internet connectivity due to the country’s power crisis, which in some instances adversely affected the productivity of WhatsApp messenger mediated curriculum knowledge transfer and acquisition processes during COVID-19 stricter lockdown.

Optimization of feature transfer based on BioTRIZ

Feature transfer is an important and practical tool to eliminate the disadvantages of old technology systems and develop new ones. However, in TRIZ feature transfer tools, there are some problems, such as an incomplete search of competitive systems and an imprecise selection of alternative systems. To solve these problems effectively, based on the basic principles of feature transfer and BioTRIZ, this study optimizes feature transfer by combining the related theories of BioTRIZ. Function-oriented search and bionic knowledge case base are used to supplement the search of competitive systems in the domain. The similarity principle is used for the strict selection of alternative systems. This method can find the competitive system more comprehensively, and provide quantitative criteria for the selection of alternative systems. By improving the terrain passing capacity of the wheeled walking mechanism, this paper proves the feasibility and effectiveness of the optimized feature transfer method.

Hydrodynamic and mass transfer correlations for SiC ceramic foam monolithic trays used in distillation column

AbstractBACKGROUNDCellular foam materials are excellent engineering materials for many applications in chemical engineering, especially process intensification of chemical conversions and separation. Recently, a silicon carbide (SiC) ceramic foam monolithic tray was developed as an excellent mass transfer tool to improve distillation and it showed an improved operational flexibility. Previous studies have revealed the effects of open cell diameter and tray thickness on the hydraulic performance and mass transfer efficiency of SiC foam monolithic trays, but relevant correlations are still missing, limiting their practical uses.RESULTSIn this study, based on the published experimental data, empirical correlations were developed to predict the hydrodynamic performance and mass transfer efficiency of SiC ceramic foam monolithic trays. The new correlations include the influence of the tray structure parameters, such as open cell (or pore) diameter and tray thickness, and of the operation conditions (such as the liquid and vapor volumetric flow rates), and the data obtained agree well with the experimental results.CONCLUSIONThe availability of such empirical correlations can be beneficial for the chemical engineering design of practical distillation processes based on SiC foam monolithic trays. © 2023 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).