Transfer Of Women Research Articles

The impact of transfer from an alongside midwifery unit to labor and delivery on birthing women: A qualitative study

ObjectiveTo explore laboring women's thoughts, feelings, and experiences of transferring from an Alongside Midwifery Unit or free-standing birth center to labor and delivery. DesignA qualitative online survey was used for this research. SettingAn Alongside Midwifery Unit in the southwestern United States. ParticipantsEight women over the age of eighteen who had transferred to labor and delivery from either the AMU or free-standing birth center. FindingsFive themes emerging from the women's transfer experiences. It was important for the women to maintain their physiologic birth ideals. The initiation of transfer, even a discussion, altered the atmosphere in the birthing room. Women experienced a range of emotions surrounding the transfer. The stories spoke to mourning the loss of physiologic birth experience. Some women expressed guilt about the potential effects on their infants. Post-birth women had realizations about their mental and physical capabilities and limitations. Key conclusionsThis pertinent study addressed the effect on women when a transfer needs to occur from an Alongside Midwifery Unit or free-standing Birth Center to the Labor and Delivery Unit. Regardless of the reason, a transfer affected all participants. The psychological impact can have significant consequences on mother and baby's wellbeing. Women need an opportunity to share their story. The fifth theme of learning about themselves mentally and physically is new and not identified in other studies. Implications for practiceClinical recommendations are proposed to improve understanding and integrate into one's mindset, care processes, and clinical practice. Post-birth care should continue for these women until they completely process and come to a resolution of their experience of transferring to labor and delivery.

Letrozole During Frozen Embryo Transfer in Women With Polycystic Ovarian Syndrome: A Randomized Controlled Trial.

To compare live-birth rates between letrozole application and artificial cycle for endometrium preparation during frozen embryo transfer (FET) cycle among women with polycystic ovarian syndrome (PCOS). A randomized controlled trial was conducted. Women with PCOS were randomized to letrozole application for ovulation induction compared with artificial cycle for endometrial preparation during FET. The primary outcome was live-birth rate per embryo transfer. Secondary outcomes included pregnancy-related outcomes, perinatal outcomes, and maternal complication rates. Assuming α=0.05 and 80% power, 186 patients per group were required to demonstrate a difference of 15% in live-birth rate: 205 patients (at least) per group were randomized to allow for a 10% dropout rate. Four hundred twenty patients were enrolled from 2018 to 2021. Two hundred ten patients were assigned to the letrozole application group, and 210 were assigned to the artificial cycle group. There was no difference in the live-birth rate (42.4% vs 42.9%, P =>.99). There was no difference in secondary outcomes, including clinical pregnancy rate (51.4% vs 56.2%, P =.378), implantation rate (51.8% vs 55.8%, P =.401), and miscarriage rate (8.6% vs 11.0%, P =.511). For perinatal outcomes, singleton birth weight was significantly higher in the artificial cycle group (3,108±56 g vs 3,301±58, P =.018), and the incidence of gestational diabetes mellitus (GDM) was significantly higher in letrozole application group (14.6% vs 5.6%, P =.050). The other outcome was no difference in maternal complications. There was no difference in pregnancy outcomes between letrozole application compared with artificial cycle for endometrial preparation in women with PCOS who underwent FET. The risk of GDM was higher in the letrozole application group, and the singleton birth weight was lower in the artificial cycle group. Chinese Clinical Trial Registry, ChiCTR1800014746.

Reproductive Outcomes of in Vitro Fertilization and Embryo Transfer in Women with Unexplained Repeated Implantation Failure are Significantly Improved with Intravenous Immunoglobulins

Reproductive Outcomes of in Vitro Fertilization and Embryo Transfer in Women with Unexplained Repeated Implantation Failure are Significantly Improved with Intravenous Immunoglobulins

Pregnancy Outcomes of Freeze-All versus Fresh Embryo Transfer in Women with Adenomyosis: A Retrospective Study.

Adenomyosis has been associated with adverse fertility and pregnancy outcomes, and its impact on the outcomes of in vitro fertilization (IVF) has received much attention. It is controversial whether the freeze-all strategy is better than fresh embryo transfer (ET) in women with adenomyosis. Women with adenomyosis were enrolled in this retrospective study from January 2018 to December 2021 and were divided into two groups: freeze-all (n = 98) and fresh ET (n = 91). Data analysis showed that freeze-all ET was associated with a lower rate of premature rupture of membranes (PROM) compared with fresh ET (1.0% vs. 6.6%, p = 0.042; adjusted OR 0.17 (0.01-2.50), p = 0.194). Freeze-all ET also had a lower risk of low birth weight compared with fresh ET (1.1% vs. 7.0%, p = 0.049; adjusted OR 0.54 (0.04-7.47), p = 0.642). There was a nonsignificant trend toward a lower miscarriage rate in freeze-all ET (8.9% vs. 11.6%; p = 0.549). The live birth rate was comparable in the two groups (19.1% vs. 27.1%; p = 0.212). The freeze-all ET strategy does not improve pregnancy outcomes for all patients with adenomyosis and may be more appropriate for certain patients. Further large-scale prospective studies are needed to confirm this result.

Pregnancy Outcomes after Frozen Embryo Transfer and Fresh Embryo Transfer in Women of Advanced Maternal Age: Single-Center Experience.

Delayed childbearing leads to increased assisted reproductive technology use by women of advanced maternal age (AMA). It is unclear whether fresh or frozen embryo transfer (FET) is the better option. We aimed to assess maternal and neonatal outcomes in patients having their first FET after a freeze-all cycle versus those having their first fresh embryo transfer (ET). We reviewed 720 women of AMA undergoing a first fresh ET (n = 375) or FET (n = 345) between January 2016 and April 2021. No significant difference in the live birth rate was found between FET and fresh ET (19.7% vs. 24.3%, p = 0.141). The clinical pregnancy rate was significantly lower in the FET group than in the fresh ET group (26.4 % (91/345) vs. 33.6% (126/375), p = 0.035), but FET resulted in higher birthweights (3217.16 ± 734.44 vs. 3003.37 ± 635.00, p = 0.037) and was associated with a lower incidence of preterm births (2.6% vs. 5.6%, p = 0.046). The risks of other maternal and neonatal outcomes did not differ significantly between the groups. Among women of AMA, the transfer of frozen embryos did not result in significantly higher rates of live birth than fresh embryos did; however, a freeze-all strategy may not be beneficial for the women of AMA.

The Effectiveness of Two Cycles of Single Embryo Transfer (Fresh + Frozen) vs. One Fresh Double Embryo Transfer in Women Treated in an Oocyte Donation Program

The Effectiveness of Two Cycles of Single Embryo Transfer (Fresh + Frozen) vs. One Fresh Double Embryo Transfer in Women Treated in an Oocyte Donation Program

Prospects of Germline Nuclear Transfer in Women With Diminished Ovarian Reserve.

Diminished ovarian reserve (DOR) is associated with a reduced quantity and quality of the retrieved oocytes, usually leading to poor reproductive outcomes which remain a great challenge for assisted reproduction technology (ART). Women with DOR often have to seek for oocyte donation, precluding genetically related offspring. Germline nuclear transfer (NT) is a novel technology in ART that involves the transfer of the nuclear genome from an affected oocyte/zygote of the patient to the cytoplast of an enucleated donor oocyte/zygote. Therefore, it offers opportunities for the generation of genetically related embryos. Currently, although NT is clinically applied only in women with serious mitochondrial DNA disorders, this technology has also been proposed to overcome certain forms of female infertility, such as advanced maternal age and embryo developmental arrest. In this review, we are proposing the NT technology as a future treatment option for DOR patients. Strikingly, the application of different NT strategies will result in an increase of the total number of available reconstituted embryos for DOR patients.

Reproductive Outcomes of Single Embryo Transfer in Women with Previous Cesarean Section.

The aim of this study is to evaluate the reproductive outcomes of patients with previous cesarean section (CS) undergoing single-embryo transfer (SET). A total of 5479 patients previously underwent CS or vaginal delivery (VD) were included. The patients with previous CS included single/double cleavage (SCT/DCT), single/double blastocyst stage embryo transfer (SBT/DBT). The comparison of reproductive outcomes between CS and VD, SET, and double-embryo transfer of CS was conducted. The main outcome measures included clinical pregnancy rate (CPR), multiple pregnancy rate (MPR), live birth rate (LBR), and cumulative live birth rate (CLBR). There were no differences in CPR and LBR between patients previously underwent CS and VD, and the preterm birth rate of multiple births in patients underwent CS were significantly higher than underwent VD. As for patients underwent CS, the CPR, MPR, and LBR were lower in patients treated with SCT than DCT in IVF/ICSI cycles. The CPR and LBR of patients treated with SCT were not statistically different compared with DCT and SBT when patients' age were younger than 35years in FET cycles, and the MPR of patients treated with SCT was lower. The CPR and LBR of patients treated with SCT were lower than DCT/SBT when patients' age were 35years or older in FET cycles. The CPR, LBR, and CLBR of patients treated with SBT were not lower than DCT in IVF/ICSI-ET, FET, and complete cycles, but the MPR was lower. Reducing the number of embryos transferred should be considered seriously for CS. SCT under the 35years of FET cycles is feasible. SBT is an effective strategy to reduce MPR of IVF/ICSI, FET, and complete cycles regardless of overall or age stratification.

Whose voice matters? An experimental examination of gender bias in intra-household decision-making

We conduct an experiment to examine gender bias in intra-household decision-making in rural Bangladesh. The experiment mimics a real-life scenario, in which a risky choice with high stakes is offered to either spouse and he/she then has to decide whether to make the decision or transfer it to the other spouse. We then observe the decision-making process under alternative experimental conditions to determine intra-household gender bias. We find that women are more likely to allow their spouses to make decisions than men are. Our findings suggest that women's transfer decisions are driven by asymmetries in both power and perceived financial capabilities.

Pregnancy Outcome in Fresh and Frozen Embryo Transfer in Women with High Estradiol Levels

Pregnancy Outcome in Fresh and Frozen Embryo Transfer in Women with High Estradiol Levels

Pregnancy Outcome in Fresh and Frozen Embryo Transfer in Women with High Estradiol Levels

Pregnancy Outcome in Fresh and Frozen Embryo Transfer in Women with High Estradiol Levels

Fertility and Neonatal Outcomes of Freeze-All vs. Fresh Embryo Transfer in Women With Advanced Endometriosis.

Background: Eutopic endometrium from women with endometriosis has functional changes in several aspects, which may largely account for the decrease in the quality of endometrial receptivity. It is of utmost importance to know whether freeze-all strategy can restore optimal receptivity in endometriotic women leading to the better ART outcomes.Methods: Retrospective study involved patients with advanced endometriosis undergoing first embryo transfer cycles during the period from March 2006 to March 2017 at a tertiary care center. After propensity score matching, there were 506 women in the freeze-all group and 255 women in fresh group. Our main outcomes included the rates of implantation, clinical pregnancy, and live birth. Subgroup analyses were performed after stratification by the number of oocytes retrieved and fertilization method. Neonatal outcomes included gestational age and birth weight z-score for singletons and multiple births.Results: In our matched cohort, the implantation, clinical pregnancy and live birth rates were statistically significantly higher in the freeze-all group compared with fresh transfer groups (34.4 vs. 25.5%, 51.8 vs. 38.8%, and 45.3 vs. 31.8%, all P < 0.001, respectively). A more beneficial effect of freeze-all cycles was found in patients who got more than 15 oocytes. Additionally, when ICSI insemination techniques were used to achieve fertilization, the advantage of freeze-all strategy was not obvious. Assessment of 382 babies showed no statistically significant difference in the mode of delivery, sex of live-born, gestational age, unadjusted median birth weight, and z-score between two study groups.Conclusion: Freeze-all strategy is an attractive option to improve the outcomes of ART for women with advanced endometriosis.

Analysis of Factors Influencing the Cumulative Pregnancy Outcome of In Vitro Fertilization-Embryo Transfer in Women Aged 35 Years and Older with Normal Ovarian Reserve

Background: To investigate the factors associating with the cumulative clinical pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) in women aged 35 years and older with normal ovarian reserve. Methods: A total of 358 patients undergoing IVF-ET at the Department of Reproductive Medicine, the First Affiliated Hospital of Xinjiang Medical University between January 2014 and June 2016 were analyzed by the Kaplan–Meier method and Cox proportional hazards model. Results: The probability of pregnancy in women 35–37 years of age and 38–40 years of age was 75.9% (95% confidence interval [CI]: 75.1%–76.7%) and 66.9% (95% CI: 65.6%–68.2%), respectively, and it was 37.8% (95% CI: 34.7%–41.1%) in women aged 40 years and older. Univariate analysis (hazard ratio [HR]: 2.50, 95% CI: 1.647–3.774) and multivariate analysis (HR: 2.17, 95% CI: 1.427–3.268) showed a correlation between the number of retrieved oocytes and successful pregnancy. Conclusions: The number of retrieved oocytes plays a key role in the pregnancy outcome of women aged 35 years and older with normal ovarian reserve. We recommend the number of retrieved oocytes be increased for women aged 35 years and older with normal ovarian reserve.

Learning and Transfer in Women's Artistic Gymnastics

The scientific argument is to highlight the methodological aspects of learning and transfer in women's artistic gymnastics. Purpose of the paper: to present the effectiveness of using transfer and biomechanical analysis in learning technical elements in women's artistic gymnastics. This approach led to the organization of a study of case in School Sports Club no.7 Dinamo Bucharest. Methods . The study was conducted during the period (11.03.2011- 10.04.12), applied to only one female gymnast 10 years old, Junior IV and III level. Gymnast's evolutions throughout training and competition preparation stages were monitored by means of video method of biomechanical analysis (World in motion), statistical-mathematical method and graphical representation. Results. The study points out the influence of transfer and biomechanical analysis in learning and perfecting the technical elements. Comparative analysis highlights the dynamics of technical elements learning on each apparatus, the relationship of transfer achievement, the detection and correction of technical mistakes and the performances obtained in competitions. The results of statistical-mathematical calculations in terms of dynamics of technical elements learning on apparatus show significant differences between tests at p<0.05, p<0.01 and not significant differences at p>0.05, while the results achieved in competitions emphasize the increase of A1 score mean (difficulty), improvement of B score mean (execution) and of final score and the achievement of good performances both in all-round finals and apparatus finals. Conclusions. The efficient use of transfer and biomechanical analysis in learning technical elements in women's artistic gymnastics contributes to improving the preparation level and getting better performances in competitions.

Secure transfer of postnatal information: The STOW project

In London, it is estimated that about 10% of women deliver in one NHS trust but receive postnatal care in another area. Transfer of postnatal information about women and babies is done via fax. A more reliable method of communication was needed. A pilot project, the Secure Transfer of Women (STOW), was undertaken in four NHS trusts in north London to test the transfer of postnatal information via email, using NHSmail between the maternity units. Communication with other NHS trusts would continue via fax. Training and IT support was provided in the pilot NHS trusts. An evaluative study undertaken showed that members of staff liked the system. They felt that email transfer improved the service for mothers and babies. Maternity units also received fewer calls from mothers to say that they had not yet had their postnatal visit. Postnatal transfer of information via email is now being rolled out across London.

Current Outcomes of Zygote Intrafallopian Transfer (ZIFT) Compared With Conventional Embryo Transfer in Women of Advanced Maternal Age: Is There a Benefit?

Background: Success rates with assisted reproductive techniques are significantly lower for women of advanced maternal age (AMA). Although early studies reported improved implantation and pregnancy rates with ZIFT compared with traditional in vitro fertilization–embryo transfer (IVF-ET) for patients with recurrent implantation failure, recent randomized controlled trials have shown no difference in outcomes. However, no studies have examined the efficacy of ZIFT specifically for patients of AMA.Objective: To determine whether ZIFT improves clinical pregnancy rates in women of AMA compared with IVF-ET.Materials and Methods: Records from January 2004 through October 2007 were reviewed, and all patients who underwent ZIFT were identified. Only patients who were ≥38 years old were included. Cycles involving donor eggs and/or frozen embryos were excluded. A control population of patients undergoing IVF-ET during the same time period was chosen using the same criteria. Two controls were selected randomly for each case.Results: 32 ZIFT and 64 IVF-ET cycles were used in the final analysis. Although the controls were chosen with the same inclusion criteria, the mean age of the ZIFT group was statistically higher than that of the controls (41.2 ± 1.7 years vs. 40.3 ± 2.1 years; P<.05). The ZIFT group had significantly more previously failed cycles than the controls (2.78 ± 2.2 vs. 0.61 ± 0.95; P<.01). The ZIFT group and the controls had a similar number of days of stimulation (9.7 ± 1.3 vs. 9.8 ± 2.2) as well as total number of ampules administered (62.9 ± 17.6 vs. 63.8 ± 22.6). There was no significant difference in the clinical pregnancy rate between the ZIFT group and the controls (25% vs. 26%). Additionally, mean implantation rates did not differ between the two groups (ZIFT 7.6 ± 0.2% vs. IVF 9.0 ± 0.2%).Conclusions: ZIFT is a viable treatment option for women of AMA. Despite a higher mean age and a higher number of previously failed cycles, ZIFT patients had pregnancy outcomes and implantation rates similar to patients undergoing IVF-ET. Therefore, ZIFT may impart an advantage over IVF-ET for older patients, especially in the setting of recurrent implantation failure. Background: Success rates with assisted reproductive techniques are significantly lower for women of advanced maternal age (AMA). Although early studies reported improved implantation and pregnancy rates with ZIFT compared with traditional in vitro fertilization–embryo transfer (IVF-ET) for patients with recurrent implantation failure, recent randomized controlled trials have shown no difference in outcomes. However, no studies have examined the efficacy of ZIFT specifically for patients of AMA. Objective: To determine whether ZIFT improves clinical pregnancy rates in women of AMA compared with IVF-ET. Materials and Methods: Records from January 2004 through October 2007 were reviewed, and all patients who underwent ZIFT were identified. Only patients who were ≥38 years old were included. Cycles involving donor eggs and/or frozen embryos were excluded. A control population of patients undergoing IVF-ET during the same time period was chosen using the same criteria. Two controls were selected randomly for each case. Results: 32 ZIFT and 64 IVF-ET cycles were used in the final analysis. Although the controls were chosen with the same inclusion criteria, the mean age of the ZIFT group was statistically higher than that of the controls (41.2 ± 1.7 years vs. 40.3 ± 2.1 years; P<.05). The ZIFT group had significantly more previously failed cycles than the controls (2.78 ± 2.2 vs. 0.61 ± 0.95; P<.01). The ZIFT group and the controls had a similar number of days of stimulation (9.7 ± 1.3 vs. 9.8 ± 2.2) as well as total number of ampules administered (62.9 ± 17.6 vs. 63.8 ± 22.6). There was no significant difference in the clinical pregnancy rate between the ZIFT group and the controls (25% vs. 26%). Additionally, mean implantation rates did not differ between the two groups (ZIFT 7.6 ± 0.2% vs. IVF 9.0 ± 0.2%). Conclusions: ZIFT is a viable treatment option for women of AMA. Despite a higher mean age and a higher number of previously failed cycles, ZIFT patients had pregnancy outcomes and implantation rates similar to patients undergoing IVF-ET. Therefore, ZIFT may impart an advantage over IVF-ET for older patients, especially in the setting of recurrent implantation failure.

A Matched Control Study of Pregnancy Rates Following In Vitro Fertilization–Embryo Transfer in Women Aged ≤37 Years With Diminished Versus Normal Egg Reserve

A Matched Control Study of Pregnancy Rates Following In Vitro Fertilization–Embryo Transfer in Women Aged ≤37 Years With Diminished Versus Normal Egg Reserve

High Dose versus Low Dose Corticoidsteroid Therapy during Ovarian Stimulation and Embryo Transfer in Women undergoing In Vitro Fertilisation-Embryo Transfer: A Prospective Randomised Study

High Dose versus Low Dose Corticoidsteroid Therapy during Ovarian Stimulation and Embryo Transfer in Women undergoing In Vitro Fertilisation-Embryo Transfer: A Prospective Randomised Study

The Effect of the Serum Progesterone Level on the Day of Human Chorionic Gonadotropin Injection on Outcome Following In Vitro Fertilization Embryo Transfer in Women Using Gonadotropin Releasing Hormone Antagonists

Background and Significance: There have been many previous studies of pregnancy rates (PRs) following in vitro fertilization (IVF) – embryo transfer (ET) according to the serum progesterone (P) at the time of human chorionic gonadotropin (hCG) injection. Various conclusions as to the negative influence of a higher serum P were reached. Most of these studies involved the use of luteal phase gonadotropin releasing hormone (GnRH) agonists.