AbstractThe literature on policy coordination between government agencies reveals little about how coordination is managed in centralized political systems. This paper, therefore, presents a dynamic and quantitative analysis of policy coordination in China based on the science and technology (S&T) policy documents issued by China’s central government agencies in the period 1978–2019. From a series of snapshots depicting inter-agency policy development in five historical stages over this timeframe, we find that (1) policy coordination has developed steadily and has mainly occurred to interpret macro strategies and put in place more detailed implementation measures. (2) Ministries under the purview of the State Council have played a leading role in policy coordination, while other types of agencies have cooperated in more supporting roles. (3) Coordination efforts have mainly focused on inclusive and national demand-oriented themes, such as high-tech industrialization, rural S&T, and social development. This research offers a panoramic view of policy coordination trajectories and mechanisms in centralized political systems. As such, it adds to the analysis methods available for quantitatively studying policy documents.