Training In Neuroradiology Research Articles

Relevance of antinuclear antibody in diagnosis and characteristics of multiple sclerosis

BackgroundCriteria for multiple sclerosis (MS) diagnosis rely upon clinical and paraclinical data that are supportive of MS in the absence of a better explanation. Patients referred for consideration of a MS diagnosis often undergo an extensive serologic workup including antinuclear antibody (ANA) testing, even when an individual already meets diagnostic criteria for MS. It is unclear whether ANA serostatus is associated with clinical outcomes in MS. The present study aims to determine if ANA seropositivity in those referred with concern for MS differs in those who meet 2017 revised McDonald criteria compared to those who did not receive a diagnosis of MS. Associations between ANA seropositivity and clinical or radiological phenotype of MS patients are also explored. MethodsThe cohort included people at least 18 years old, referred to our tertiary care MS center with concern for MS (regardless of prior diagnosis) who had an ANA test with known titer completed within one year of first evaluation. Electronic health record (EHR) charts were manually reviewed, and MRIs underwent blinded review by a radiologist with training in neuroradiology. Diagnosis of MS was determined by a neuroimmunologist and was based on 2017 revised McDonald Criteria. Results are reported as odds ratios from multivariable logistic regression analyses adjusted for age, sex at birth, race, smoking history, personal history of comorbid autoimmune conditions, and family history of autoimmunity. Within the MS cohort, similar analytical models were performed to assess association between ANA and clinical and radiological characteristics. ResultsA final cohort of 258 patients was analyzed (out of 542 referrals): 106 nonMS and 152 with MS. There was no association between MS (vs. nonMS) diagnosis and ANA status (ANA positive n = 74) in the multivariable models (OR 1.5, 95 % CI 0.82, 2.72, p = 0.20). Among those with MS, there was no association of ANA seropositivity with the odds of atypical brain MRI features, number of cardinal MRI areas involved, location of MRI lesions, or of having an atypical presentation of first demyelinating event. Black race (OR 2.8, 95 % CI 1.27, 6.26, p = 0.01) and family history of autoimmunity (OR 2.1, 95 % CI 1.09, 3.98, p = 0.03) were independently associated with increased odds of ANA positivity. Within the MS cohort analysis, progressive MS (PMS; vs relapsing-remitting MS), a covariate in the model, appeared to be at higher odds of being ANA positive (OR 3.6, 95 % CI 1.03, 13.05, p = 0.046) but only when assessing mean area of cardinal MS locations. ConclusionsWhile ANA testing does not appear to be useful in distinguishing MS from non-MS, it remains less clear as to whether it may be associated with differences in the clinical course of MS (relapsing-remitting vs progressive). Future studies should aim to systematically evaluate whether those who are ANA positive are more likely, in well-designed and representative prospective cohorts, to be diagnosed with or develop progressive MS. Whether a positive ANA early in MS is associated with increased risk over time of developing or diagnosing another systemic autoimmune disease would also be of interest.

Diagnostic and interventional neuroradiology training in the UK: a national trainee survey

Training structure in neuroradiology can be variable, nationally and internationally. Globally, there is a trend towards standardised training pathways, curricula and targeted competencies. Currently, there is limited understanding of the structure of neuroradiology training in the UK. This survey aims to: [1] identify different contemporary models of neuroradiology training in the UK, [2] compare UK trainees' commitments against national and international standards, and [3] understand whether career expectations match the predicted future demands of neuroradiologists. A survey was developed after consultation with BSNR and UKNG representatives. The eligibility criteria included current neuroradiology trainees in the UK with at least 3 months of experience or had recently completed neuroradiology training, but less than 18 months had elapsed since achieving a certificate of completion of training. A total of 50 trainees responded to the survey; 26 (52%) diagnostic neuroradiologists (DNRs) and 24 (48%) interventional neuroradiologists (INRs) with an overall mean age of 33 years. The mean duration of training at the time of survey was 18 months. The survey details trainee demographics, experience at work, research and teaching commitments and future goals. Most respondents are satisfied with their training and 90% want to remain in the UK after completion of training. There is room for improvement but the future of training and working in neuroradiology seems promising internationally, with ever-evolving techniques and developments. Advances in knowledge: This study evaluates neuroradiology training in the UK to enhance the training of future neuroradiologists, and safeguard the future of the speciality.

Education Research: Neuroradiology Curriculum and Competencies Among Canadian Adult Neurology Residency Programs: A Cross-Sectional Study.

While benefitting from neuroradiologists' reports, neurologists use their own image interpretation to guide clinical decisions, especially in acute care settings. This calls for robust neuroradiology training in neurology residency, informed by current educational gaps and practices. This study aims to (1) characterize the formal neuroradiology curriculum among Canadian neurology residency programs; (2) assess neurology residents' neuroimaging interpretation competencies; and (3) define neurology residents' and program directors' (PDs) attitudes toward the current curriculum and future directions. Anonymous surveys were sent to Canadian neurology residents and PDs, querying neuroradiology learning activities, imaging modalities covered, assessment modalities, perceived residents' competencies to interpret different modalities, and attitudes regarding neuroradiology training. Residents were asked to interpret 15 neuroimaging cases. Descriptive and inferential analyses were performed. Potential differences in residents' interpretation success rates by seniority, self-perceived proficiency, and perception of curriculum sufficiency were examined using 2-tailed Welch tests with a 95% CI and Holm-Bonferroni comparison adjustment. Statistics were computed using Excel. Seventy-eight (32.6%) residents and 11 (68.8%) PDs participated. Ten of 11 PDs reported including a mandatory neuroradiology rotation, and 9/11 offered a formal neuroradiology curriculum covering head CT, head and neck CT angiography (CTA), spine MRI, and head MRI. Programs predominantly offered additional didactic lectures (9/11), teaching cases (8/11), and imaging websites (8/11). Most of the residents agreed with a minimum 1-month long rotation and desired regular didactics from neuroradiologists. Residents favored learning about head MRI (88.5%), head and neck CTA (76.9%), and spine MRI (69.2%). Senior residents' self-perceived competencies were highest for head CT, head MRI, and head and neck CTA, but lower than PDs' perception. Senior residents had greater interpretation scores than juniors (84.5% ± 13.2% vs 69.1% ± 19.9%; p < 0.0001). Most PDs (7/11, 63.6%) expressed satisfaction with current curricula vs 32.1% of residents. PDs identified time and educator shortages as main barriers to increased training. Neuroradiology training varies among programs. Residents expressed strong interest in commonly taught modalities, for which they also expressed high self-perceived competencies. However, PDs expressed greater satisfaction than residents with the current training. Leveraging interactions with neuroradiologists and online case-based learning while emphasizing trainees' interests can enhance postgraduate neuroradiology training for this useful skill.

Interexpert agreement between neuroradiologists in the diagnosis of middle cerebral artery stroke by computed tomography

Background. To evaluate the diagnostic accuracy of radiologists with a wide range of experience and training in emergency neuroradiology and other specialty hospitals, as well as the level of inter-experts’ agreement regarding CT signs of ischemic stroke.Material and methods. Our study included a retrospective cohort of 100 patients who underwent NCCT, CT angiography (mCTA) and CT perfusion in St. Petersburg clinical hospital. Fifty patients had confirmed middle cerebral artery ischemic stroke. The study also randomly included fifty patients in whom this diagnosis was excluded, including on the basis of dynamic follow-up as part of further clinical evaluation and follow-up CT scan of the brain. All 100 CT were reviewed by 21 radiologists who independently assessed each study for CT evidence of ischemic stroke. Statistical analysis included the Kappa-Fleiss coefficient ( ) calculation of agreement for each sign of ischemic stroke, specificity, sensitivity, and accuracy of detection of these changes.Results. The staff radiologist’s mean experience in emergency neuroradiology affects both diagnostic performance and consistency for detection of most CT features of ischemic stroke. At the same time, experience does not affect the diagnostic efficiency of radiologists with no experience in stroke assessment. The most highly specific and reproducible sign of ischemic stroke was the hyperdense middle cerebral artery sign, and the most ambiguous diagnostic sign was the gyral effacement. At the same time, all radiologists, regardless of length of service record and experience in emergency neuroradiology, are prone to over-diagnosis.Conclusion. Further search for tools and solutions is needed to level out interexpert variability regarding assessment of ischemic CT signs, since this problem has high clinical importance.

The 'Sic Vos non Vobis' of Interventional Radiology - Rebranding and modernising the Interventional Specialities of Radiology in Australia and New Zealand.

The 'Sic Vos non Vobis' of Interventional Radiology - Rebranding and modernising the Interventional Specialities of Radiology in Australia and New Zealand.

Job-Readiness After Pediatric Neuroradiology Training: Defining Trainee Needs

To describe and analyze the pediatric neuroradiology implicit curriculum for general-pediatric and neuro-pediatric radiology fellowship training in order to define specific trainee needs and inform an explicit pediatric neuroradiology curriculum. A focus group of pediatric radiologists, pediatric neuroradiologists and fellows was conducted to create a needs assessment questionnaire that focused on training experience, current job, and a list of essential competency items. The questionnaire was distributed to 175 members of the Society for Pediatric Radiology. Data were derived from categorical and continuous survey variables. Using an inductive approach, we analyzed and systematically inspected the data to derive themes regarding trainee needs and how they might inform an explicit curriculum. Fifty-seven pediatric radiologists (response rate of 33%) responded to the survey. Sixty-three percent of respondents were fellowship trained in general pediatric radiology, 21% in pediatric neuroradiology, and 16% in both. In their current jobs, 75% of respondents were responsible for interpreting some pediatric neuroradiology. 50% or greater reported limited or no fellowship instruction in five areas of imaging interpretation: fetal neuroimaging; ear and/or nose and/or throat imaging; head and neck imaging; neuroembryology; neuro-spectroscopy and four areas of technical skills and/or image quality: reducing imaging time; choice of contrast agents; sedation; understanding clinical management pathways. Trainees endorse inadequate training in certain aspects of imaging interpretation and technical skills which are known to remain a significant and vital aspect of pediatric neuroradiology practice, revealing an opportunity to emphasize these aspects in an explicit curriculum and dedicate educational resources towards this cause.

Recommendations for Neuroradiology Training during Radiology Residency by the American Society of Neuroradiology Section Chiefs Leadership Group.

The American Society of Neuroradiology [ASNR] Section Chiefs Leadership Group strongly feels that residency education in neuroradiology should become more standardized and wishes to make recommendations and facilitate the ability of residency programs to educate and train their residents in

Diagnostic Neuroradiology Subspecialty Training: 1 Versus 2 Years; the Canadian Perspective

Canada began a national reform of its post-graduate medical education training programs to a Competence By Design (CBD) model. Trends from accredited neuroradiology programs from the past 10 years were investigated to inform educators and stakeholders for this process. A 13-question electronic survey was sent to program directors of all 8 accredited neuroradiology training programs in Canada. Data was requested for each year on the 2008-2019 graduating classes. Questions pertained to program enrolment; program completion; post-training employment; and the sufficiency of 1-year training programs. Response rate was 100%. Over the timeframe studied, the 2-year programs increased in size (P = 0.007), while the 1-year programs remained steady (P = 0.27). 12.2% of trainees enrolled in the 2-year program dropped out after 1 year, and were considered 1-year trainees thereafter. A higher proportion of 2-year trainees obtain positions within academic institutions (89.5 vs 67.2%, P = 0.0007), whereas a higher proportion of 1-year trainees obtain positions within non-academic institutions (29.3 vs 8.1%, P = 0.0007). A higher proportion of those with Canadian board certification in diagnostic radiology who completed a 2-year program obtained a position within a Canadian academic institution compared to non-certified 2-year trainees (P < 0.001). 71.4% of program directors agreed that a 1-year program was sufficient for non-academic staff positions. The length of the training program has significant impact on employment in academic vs non-academic institutions. This information can be used to guide the upcoming CBD initiative for neuroradiology programs.

Neuroradiology training in EU: international survey of 31 countries within UEMS frame

ObjectiveTo assess the current framework of interventional and diagnostic neuroradiology in EuropeMethodsThe UEMS (European Union of Medical Specialists) Section of Radiology and the subspecialty UEMS Division of Neuroradiology collected by e-mail a survey on the situation of diagnostic and Interventional Neuroradiology’ training and practice in Europe. The questionnaire was sent to the national delegates from 31 UEMS member countries, belonging to the European Union, the European Economic Area and the Council of Europe. In case of uncertain or discordant replies, the survey envisaged the involvement of neuroradiology scientific societies’ experts for providing a decisive answer.ResultsA formal post-residency training in diagnostic and interventional neuroradiology is provided respectively by 12/31 and 20/31 of the European countries. Currently, for becoming neuroradiologist in a country without fellowship program, a radiologist should (1) get subspecialty credits, (2) follow training inside national or international neuroradiology departments, or (3) perform the main reporting activity in neuroradiology.In nearly 2/3 of the States included in the survey, the neurointerventional procedures are provided by radiologists (22/31) and in the most frequent scenario a specific training in neurovascular is required to all radiologist or non-radiologist candidates (18/31).ConclusionsThe European framework of neuroradiology’s training and practice that emerged through this survey is fragmented, but there is an increasing attention by European scientific societies and institutions to create a common path of training and practice that can guarantee high educational and patient care standards.

Differences in Outcomes Associated With Individual Radiologists for Emergency Department Patients With Headache Imaged With CT: A Retrospective Cohort Study of 25,596 Patients.

OBJECTIVE. The purpose of this study was to determine whether diagnostic radiologists impart variation into resource use and patient outcomes in emergency department (ED) patients undergoing CT for headache. MATERIALS AND METHODS. This was a single-institution retrospective quality assurance cohort study of 25,596 unique adult ED patients undergoing head CT for headache from January 2012 to October 2017. CT examinations were interpreted by 55 attending radiologists (25 neuroradiologists, 30 radiologists of other specialties) who each interpreted a mean of 1469.8 ± 787.9 CT examinations. Risk adjustment for variables thought to influence outcome included baseline risk (demographics, Elixhauser comorbidity score), clinical factors (vital signs, ED triage and pain scores, laboratory data, hydrocephalus, prior intracranial hemorrhage, neurosurgical consultation within last 12 months), and system factors (time of CT, physician experience, neuroradiology training). Multivariable models were built to analyze the effect of individual radiologists on subsequent outcomes. Any p value less than 0.007 was considered significant after Bonferroni correction. RESULTS. The study found 57.5% (14,718/25,596) of CT interpretations were performed by neuroradiologists, and most patients (98.1% [25,119/25,596]) had no neurosurgical history. After risk adjustment, individual radiologists were not an independent predictor of hospital admission (p = 0.49), 30-day readmission (p = 0.30), 30-day mortality (p = 0.14), or neurosurgical intervention (p = 0.04) but did predict MRI use (p < 0.001; odds ratio [OR] range among radiologists, 0.009-38.2), neurology consultation (p < 0.001; OR range, 0.4-3.2), and neurosurgical consultation (p < 0.001; OR range, 0.1-9.9). CONCLUSION. Radiologists with different skills, experience, and practice patterns appear interchangeable for major clinical outcomes when interpreting CT for headache in the ED, but their differences predict differential use of downstream health care resources. Resource use measures are potential quality indicators in this cohort.

Standards for European training requirements in interventional neuroradiology guidelines by the Division of Neuroradiology/Section of Radiology European Union of Medical Specialists (UEMS), in cooperation with the Division of Interventional Radiology/UEMS, the European Society of Neuroradiology (ESNR), and the European Society of Minimally Invasive Neurological Therapy (ESMINT)

This document sets out standards for training in interventional neuroradiology (INR) in Europe. These standards have been developed by a working group of the European Society of Neuroradiology (ESNR) and...

Standards for European training requirements in interventional neuroradiology

This document sets out standards for training in Interventional Neuroradiology (INR) in Europe. These standards have been developed by a working group of the European Society of Neuroradiology (ESNR) and the European Society of Minimally Invasive Neurological Therapy (ESMINT) on the initiative and under the umbrella of the Division of Neuroradiology/Section of Radiology of the European Union of Medical Specialists (UEMS).

In Memoriam Grant Hieshima, MD: 1942–2019: Pioneer, Mentor, Visionary, Friend

Grant Hieshima, MD died unexpectedly on August 9, 2019, at the age of 77, while enjoying one of his lifelong passions, deep-sea fishing, with his son Michael at his side....

CT angiograms of the neck in strangulation victims: incidence of positive findings at a level one trauma center over a 7-year period.

To determine the incidence of acute findings diagnosed with computed tomography angiography (CTA) of the neck among emergency department patients presenting with strangulation injury. This institutional review board-approved, HIPAA-compliant retrospective review was performed at our academic urban level 1 trauma center. The PACS database was queried for all consecutive patients who had CTAs of the neck performed for the exam indication of strangulation between January 1, 2009, and April 30, 2016, resulting in 142 included patients. Analysis of the individual cases was then performed, recording any positive results, with clinical findings classified using, when possible, standardized terminology found in the literature. Frequency of acute injury in the CTA neck examinations was determined with the calculation of 95% confidence interval (CI) and positive clinical findings were evaluated by calculation of prevalence. Additionally, two board certified radiologists with training in neuroradiology assessed the cases for vascular injury. There were 142 patients who met inclusion criteria (average age, 32.6years) and 116 (81.7%) patients were female. CTA of the neck revealed 21 patients to have acute injuries (15.5%, 95% CI 9.5, 21.4) including 6 initially reported vascular injuries (4.2%, 95% CI 0.9, 7.5). Although neck pain (73, 51.4%), loss of consciousness (67, 47.2%), and headache (31, 21.8%) were frequently reported in the ROS, their predictive value of vascular injury was weak (4.1%, 4.5%, and 3.2%, respectively). On physical exam, redness/bruising of the neck (73, 51.4%) and neck tenderness (47, 33.1%) were both the most common and had the highest prevalence (19.2% and 12.8%, respectively), however, when selecting for vascular injuries alone were found to have low predictive yield (vascular injury 4.1% and 2.1%, respectively). The above statistics were based on the initial radiologist report and Emergency Department findings. After retrospective review, 3 Grade 1 BIFFL vascular injuries were identified (2.1%), with one false negative case (0.7%). Performing CTA of the neck after acute strangulation injury rarely identifies clinically significant findings, with vascular injuries proving exceedingly rare. As positive vascular injury could not be clinically predicted by history and physical examination, prospective validation of a clinical prediction rule in this population is warranted.

Missed Opportunity: Neuroradiology Training Programs and Social Media.

OBJECTIVE. The purpose of this study was to ascertain the degree to which the academic neuroradiology community is embracing social media in its messaging. The hypothesis was that, compared with peer neurosurgery and neurology programs, a majority of neuroradiology programs would actively engage through Facebook and Twitter accounts. MATERIALS AND METHODS. An Internet search was conducted for Facebook, Twitter, LinkedIn, and Instagram accounts for the 75 National Resident Matching Program-registered U.S. neuroradiology fellowship programs and their division chiefs and for the neurosurgery and neurology social media accounts of the same institutions. The content and audience responses of the neuroradiology accounts were categorized. RESULTS. Only 8 of 75 neuroradiology programs had one or more social media accounts. Neurosurgery (odds ratio, 5.9; 95% CI, 2.5-14.0) and neurology (odds ratio, 3.2; 95% CI, 1.3-7.9) had a significantly greater social media presence than neuroradiology did. Larger neuroradiology programs (five or more fellowship positions) had significantly greater likelihood (odds ratio, 7.6,; 95% CI, 1.6-36.4) of having social media accounts compared with those with fewer than five positions. Division chiefs had accounts on LinkedIn more than other media. Few neuroradiology chiefs actively engaged professionally on Facebook and Twitter. Most neuroradiology programs used social media more for recruitment and program information than for education, research, or patient information. CONCLUSION. Most neuroradiology training programs do not have social media accounts and do not use social media for education, engagement, recruitment, or research promulgation. Neurosurgery and neurology programs have more but still limited World Wide Web representation. There is an opportunity for neuroradiology programs to have greater impact in this arena.

Neuroradiology in Azerbaijan and in the Netherlands: A healthcare assessment from the neurologist’s perspective

Background. Referring physicians are valuable sources of information for radiologist to improve quality in radiology. In differenthealthcare systems neuroradiology has developed differently. Healthcare in Azerbaijan is developing and investmentstake place both in infrastructure and knowledge. Tools to compare healthcare in Azerbaijan and western countries can help toguide these improvements by providing detailed information about a specific field resulting in a more focused approach.Methods. A survey covering the field of neuroradiology was developed, with a variety of items including the availability ofequipment, the contentment with the radiological report, the experience of the neurologist, and factors omitting neurologicalimaging. Data was collected both in Azerbaijan and the Netherlands.Results. In both countries most neurologist do not receive formal neuroradiology training. The data demonstrate a higher availabilityof advanced computed tomography (CT) and magnetic resonance imaging (MRI) machines in the Netherlands comparedwith Azerbaijan, and a higher experience with requesting imaging and case reading for the Dutch respondents. The financialsituation of the patient can be a reason for Azerbaijan neurologists to omit imaging (due to the establishment of CT and MRIin most cases in specialized and private centers).Conclusion. The presented survey allows comparison of neuroradiological healthcare between countries in general, and identificationof required preconditions to improve collaboration between neurologists and radiologists. A future lower financialthreshold for imaging and a future increase in availability of PACS (picture archiving and communication system) will facilitatethe improvement of neuroradiological skills of Azerbaijan neurologists. Both Dutch and Azerbaijan neurologists considerweekly clinical neuroradiological conferences together with radiologists useful to improve their skills.

NEURORADIOLOGY IN AZERBAIJAN AND THE NETHERLANDS: A HEALTHCARE ASSESSMENT FROM THE NEUROLOGIST’S PERSPECTIVE

Background. Referring physicians are valuable sources of information for radiologist to improve quality in radiology. In different healthcare systems neuroradiology has developed differently. Healthcare in Azerbaijan is developing and investments take place both in infrastructure and knowledge. Tools to compare healthcare in Azerbaijan and western countries can help to guide these improvements by providing detailed information about a specific field resulting in a more focused approach. Methods. A survey covering the field of neuroradiology was developed, with a variety of items including the availability of equipment, the contentment with the radiological report, the experience of the neurologist, and factors omitting neurological imaging. Data was collected both in Azerbaijan and the Netherlands. Results. In both countries most neurologist do not receive formal neuroradiology training. The data demonstrate a higher availability of advanced computed tomography (CT) and magnetic resonance imaging (MRI) machines in the Netherlands compared with Azerbaijan, and a higher experience with requesting imaging and case reading for the Dutch respondents. The financial situation of the patient can be a reason for Azerbaijan neurologists to omit imaging (due to the establishment of CT and MRI in most cases in specialized and private centers). Conclusion. The presented survey allows comparison of neuroradiological healthcare between countries in general, and identification of required preconditions to improve collaboration between neurologists and radiologists. A future lower financial threshold for imaging and a future increase in availability of PACS (picture archiving and communication system) will facilitate the improvement of neuroradiological skills of Azerbaijan neurologists. Both Dutch and Azerbaijan neurologists consider weekly clinical neuroradiological conferences together with radiologists useful to improve their skills.

Benchmarking Lumbar Puncture Fluoroscopy Time during Fellowship Training.

We sought to establish a guide for identifying fellowship competency in performing fluoroscopically guided lumbar punctures. With a linear mixed-effects model, we compared the fluoroscopy time between the first and last 3 months of neuroradiology training. During 7 years, 55 fellows performed 1142 and 861 lumbar punctures in the first and last quarters of training. A target fluoroscopy time of 0.26 minutes, the upper 95% confidence interval, can serve as a fellowship benchmark for successfully achieving competence in fluoroscopically guided lumbar punctures.

Can Medical Professionals with Minimal-to-No Neuroradiology Training Monitor MS Disease Progression Using Semiautomated Imaging Software? (P2.151)

Can Medical Professionals with Minimal-to-No Neuroradiology Training Monitor MS Disease Progression Using Semiautomated Imaging Software? (P2.151)

Perspective on “China's Medical Education and Interventional Neuroradiology Training”

More than any neurosurgical specialty, neurointerventional surgery is truly a multidisciplinary specialty, and training modern neurointerventionalists poses significant challenges. What was originally the domain of neuroradiologists, neurointerventional surgery now largely comprises neuroradiologists, neurosurgeons, and neurologists with respective and potentially competing organizations, journals, and interests. Resident education for each of these specialties is often vastly different with regard to the spectrum of cerebrovascular disease encountered and the clinical management of that disease. Endovascular exposure during residency is also varied, not just among specialties, but even among different training programs within a given specialty. All of these factors combine to make it difficult to ensure uniform training for neurointerventional fellows.