Introduction. The article presents the problem of professional self-realization and self-determination of a young scientist in the conditions of transformation of educational and scientific institutions. The sharpness of it is added by the diversification of professional guidelines, supported by the vagueness of state policy in the field of fundamental science development, as well as its orientation to the use of quantitative assessment parameters.Purpose setting. The problem of professional self-determination and self-realization of a young scientist is considered not through the prism of postgraduate training and quantitative criteria for evaluating its effectiveness, but through the analysis and comparison of the dominant motives for carrying out research activities by young scientists, both in Russia and abroad, as well as the factors that determine its formation. This angle of the study represents the novelty of the work.The research methodology is based on the application of structural-functional and institutional approaches, as well as theories that reveal the process of self-determination, self-realization and motivation.Results. The author provides a wide range of examples of studying the phenomenon of self-realization in the scientific environment, both by Russian and foreign researchers. It shows the general and particular that distinguishes the process in Russia and other countries.Conclusions. The main problem of self-determination and self-realization is not so much the satisfaction of material needs as the strengthening of the meaning- forming component of research activity. It should be supported by transparency of criteria focused on the evaluation of the process, the development of the professional environment of interaction, including through improving the social status of scientists representing the middle age group. In this case, it will create prerequisites for young researchers to be confident in the future in science and education.