Optimization is a classical yet fast-growing field. It has been playing vital roles in many areas of Science, Engineering, Business, and our daily life. In recent years, the vast applications of optimization and the tremendous advancement in computing speed (even parallel computers) have created many new research frontiers and challenges both theoretically and numerically for the researchers and practitioners in the field of optimization. In this special issue, papers in continuous optimization as well as combinatorial optimization cover theoretical investigations, numerical experiments, and practical applications. The paper by Xiaoling Fu and Bingsheng He studies a class of monotone variational inequalities with linear constraints. Strong theoretical achievement and some efficient numerical scheme have been obtained. Numerical experiments, including some traffic equilibrium problems, are presented. In the paper by Min Li and Xiao-Ming Yuan, they focus on some nonlinear complementarity problems; by using the logarithmic-quadratic proximal method, a new efficient computing scheme is proposed. Solid convergence and attractive numerical results are presented. The paper by Hongyu Zhang and Yiju Wang proposes a new type of solution methods for the split feasibility problem. Its global convergence is proved under mild conditions, and preliminary numerical results are reported to show the efficiency of the proposed method. The next three papers focus on the combinatorial optimization. The paper by Qizhi Fang, Rudolf Fleischer, Jian Li, and Xiaoxun Sun is devoted to core stability