Traditional Preventive Measures Research Articles

THE TREND OF PEMALI PRACTICES IN PREVENTING MISFORTUNE IN MARRIAGE FROM MAQASHID SHARIAH PERSPECTIVE: A STUDY OF LUYO COMMUNITY BELIEFS

This research aims to examine the traditional beliefs surrounding pemali in marriage practices within the Luyo community. Specifically, it explores the community’s understanding of pemali, the reasons behind these beliefs, and how they function as preventive measures to avoid misfortune or failure in marriage. The study investigates the cultural significance of pemali and its enduring influence on contemporary marriage rituals. The study employs a qualitative approach, using ethnographic methods such as participant observation and in-depth interviews with key informants from the Luyo community. Data were collected through fieldwork and analyzed thematically to uncover the underlying motivations and meanings attached to pemali practices. The research also draws on a literature review of similar cultural practices in Indonesia to provide a comparative analysis. The findings reveal that the Luyo community views pemali as a set of prohibitions imposed on brides and grooms to prevent calamities such as accidents or other misfortunes. These beliefs are deeply rooted in empirical experiences, either from personal encounters or the collective memory of the community. The study also highlights that pemali is perceived as a spiritual safeguard, with marriage seen as a long and sacred journey that is vulnerable to the interference of evil forces. Therefore, pemali serves as a protective measure to ensure marital success. This research contributes to the understanding of the persistence of traditional beliefs in modern marriage practices, specifically in the context of pemali. While previous studies have explored cultural beliefs in other regions of Indonesia, this study offers a unique focus on the Luyo community's specific practices and the experiential basis for their adherence. It provides new insights into how traditional beliefs are maintained and transmitted through generations in a contemporary setting. The study has implications for understanding the intersection of cultural traditions and modern life, particularly in the context of marriage. It sheds light on how communities like Luyo continue to rely on traditional preventive measures in marriage, which could influence both social practices and future research on cultural preservation. Additionally, these findings may inform local policymakers and cultural practitioners about the importance of integrating respect for traditional beliefs with evolving social norms.

Surface Prereacted Glass Ionomer Varnish as a Multifaceted Anticaries Agent: Investigating its Inhibitory Effects on Demineralization and Biofilm Formation on Primary Tooth Enamel.

Dental caries remains a significant oral health concern, particularly in young children. With an increasing interest in preventive strategies, pediatric and preventive dentistry research is now more focused on developing newer materials and techniques to coat the primary teeth to prevent the onset of new carious lesions. While traditional preventive measures such as fluoride application and sealants have been effective in reducing caries incidence, there is still a need for innovative approaches. To evaluate the effectiveness of surface prereacted glass ionomer (S-PRG) light-cured varnish in inhibiting demineralization of primary teeth enamel. In this study, primary teeth samples were randomly divided into two groups: the control group received no coating, while the test group received an S-PRG filler coat. The samples were allowed to demineralize, and various analyses, including Fourier transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM), energy-dispersive X-ray analysis (EDX), and Vickers microhardness analysis, were conducted. Additionally, biofilms of Streptococcus mutans and Enterococcus faecalis were developed on solid surfaces such as microtiter plates, glass, and dentures, and the quantity of bacterial biofilm was measured using crystal violet assay and fluorescence microscopy. The study results showed that the primary teeth samples in both groups had a significantly greater calcium content than the controls. The S-PRG group demonstrated a significant reduction in the development of biofilms of S. mutans and E. faecalis, as well as bacterial attachment to glass and denture surfaces compared to the control group, as indicated by crystal violet assay and fluorescence microscopy. The findings of this study suggest that S-PRG filler-containing coating materials have the potential to prevent demineralization and inhibit S. mutans and E. faecalis biofilm formation on primary tooth enamel. These results are promising and may have implications for the prevention of dental caries in young children. Fernandes RM, Kumar S, Suvarna R, et al. Surface Prereacted Glass Ionomer Varnish as a Multifaceted Anticaries Agent: Investigating its Inhibitory Effects on Demineralization and Biofilm Formation on Primary Tooth Enamel. Int J Clin Pediatr Dent 2024;17(9):1049-1056.

Artificial Intelligence and Machine Learning in Predicting Intradialytic Hypotension in Hemodialysis Patients: A Systematic Review.

Intradialytic hypotension (IDH) is a common and potentially life-threatening complication in hemodialysis patients. Traditional preventive measures have shown limited effectiveness in reducing IDH incidence. This systematic review evaluates the existing literature on the use of artificial intelligence (AI) and machine learning (ML) models for predicting IDH in hemodialysis patients. A comprehensive literature search identified five eligible studies employing diverse AI/ML algorithms, including artificial neural networks, decision trees, support vector machines, XGBoost, random forests, and LightGBM. These models utilized various features such as patient demographics, clinical data, laboratory findings, and dialysis-related parameters. The studies reported promising results, with several models achieving high prediction accuracies, sensitivities, specificities, and area under the receiver operating characteristic curve values for predicting IDH. However, limitations include variations in study populations, retrospective designs, and the need for prospective validation. Future research should focus on multicenter prospective studies, assessing clinical utility, and integrating interpretable AI/ML models into clinical decision support systems.

Malaria vaccination in Africa: A mini-review of challenges and opportunities.

Malaria remains an endemic public health concern in Africa, significantly contributing to morbidity and mortality rates. The inadequacies of traditional prevention measures, like integrated vector management and antimalarial drugs, have spurred efforts to strengthen the development and deployment of malaria vaccines. In addition to existing interventions like insecticide-treated bed nets and artemisinin-based combination therapies, malaria vaccine introduction and implementation in Africa could drastically reduce the disease burden and hasten steps toward malaria elimination. The malaria vaccine rollout is imminent as optimistic results from final clinical trials are anticipated. Thus, determining potential hurdles to malaria vaccine delivery and uptake in malaria-endemic regions of sub-Saharan Africa will enhance decisions and policymakers' preparedness to facilitate efficient and equitable vaccine delivery. A multisectoral approach is recommended to increase funding and resources, active community engagement and participation, and the involvement of healthcare providers.

AI Empowers Data Mining Models for Financial Fraud Detection and Prevention Systems

With the rapid development of Internet finance, the problem of financial fraud has become increasingly prominent, which has brought severe challenges to the security and stability of the financial industry. This paper aims to use artificial intelligence (AI) technology to empower data mining models to build an efficient financial fraud detection and prevention system. First of all, through the analysis of the development trend of Internet finance and the current situation of financial fraud, the limitations of traditional prevention and control measures in the face of big data and complex fraud modes are revealed. Secondly, the paper introduces the application prospect of AI technology in the financial field, especially the advantages and potential in data mining and fraud detection. Then, the data mining techniques adopted are discussed in detail, including the application of machine learning-based model recognition and artificial intelligence algorithms, as well as data preprocessing and feature engineering in big data environment. Further, the paper describes the system architecture design and key technology implementation, including model training and optimization, real-time monitoring and early warning solutions. Finally, through the in-depth analysis and evaluation of the experimental results, the paper verifies the remarkable effect and feasibility of the system in financial fraud detection and prevention, and provides a new technical guarantee and risk management strategy for the financial industry. The experimental results show that the model has achieved good results in the actual data in the financial field, and provides effective technical guarantee and support for financial security.

Mediation effect of stroke recurrence in the association between post-stroke lactate dehydrogenase and functional disability.

We aimed to use lactate dehydrogenase (LDH) as a marker of inflammation burden and quantify post-stroke inflammation's direct and indirect effect on functional disability. We analyzed 5,129 patients with acute ischemic stroke (AIS) admitted to Shenyang First People's Hospital. Stroke recurrence and functional outcome measured by the modified Rankin Scale (mRS) were assessed at 90 days. Functional disability was defined as mRS score > 2. Receiver operating characteristic curve and restricted cubic spline (RCS) analysis were conducted to illustrate the associations between LDH levels and 90-day functional outcomes in patients with AIS. Mediation analyses were performed to examine the potential causal chain in which stroke recurrence may mediate the relationship between LDH and functional outcome. Positive correlation between LDH and hs-CRP was found and mediation effects of stroke recurrence in the association between LDH or hs-CRP and functional disability were both less than 20%. Sensitivity analyses in different subgroups showed comparable results. Among 5,129 included AIS patients, the median (IQR) level of LDH was 186 (161-204.4) U/L. Functional disability was seen in 1200 (23.4%) patients and recurrence was observed in 371(7.2%) patients at 90-day follow-up. Each standard deviation increase in the concentration of LDH was linked to an increased risk of functional disability (adjusted odds ratio[aOR], 1.07; 95%CI,1.04-1.09) and stroke recurrence (aOR,1.02; 95%CI, 1.01-1.04) within 90 days. The highest quartile of LDH (>204.2 U/L) had an elevated risk of suffering functional disability (aOR, 1.21; 95%CI, 1.00-1.47) and recurrence (aOR, 1.21; 95%CI,1.00-1.47) compared with the lowest quartile of LDH (<161 U/L). Stroke recurrence during follow-up explained 12.90% (95%CI, 6.22-21.16%) of the relationship between LDH and functional disability. Positive correlation between LDH and hs-CRP was found and mediation effects of recurrence in the association between LDH or hs-CRP and functional disability were both less than 20%. Sensitivity analyses in different subgroups showed comparable results. The relationship between LDH and functional disability at 90 days among AIS patients is partially mediated by stroke recurrence, accounting for less than 20%. LDH deserves equal attention as hs-CRP in predicting recurrence and functional outcome. In addition to traditional secondary prevention measures, innovative anti-inflammatory strategies warrant further investigation.

Prospects for the use of probiotic organisms to develop alternative strategies for disinfection and prevention of infectious diseases

Introduction: An important feature of microorganisms is the ability to adapt to adverse external influences, including the development of multiple antimicrobial resistance, leading to such negative consequences for humans as nosocomial infections, problems with cleaning rooms, medical and industrial equipment. The active use of chemical disinfectants for high-quality disinfection and cleaning has a number of disadvantages, including the risks of pathogens with new mechanisms of resistance to antimicrobial agents. The search for new, effective and safe antimicrobial agents as an alternative to chemical disinfectants is relevant. The use of probiotic strains of microorganisms, including lactic acid bacteria, in this capacity may be a promising area of research.Objective: to analyze the literature data on studies of the potential of probiotic organisms, including lactic acid bacteria, to develop alternative disinfection and prevention strategies.Materials and methods: This review of the subject field has been prepared based on the guiding principles of PRISMA-ScR. SCOPUS, Google Scholar, and RSCI databases were used. The works in Russian and English were considered, for the period 1995-2023.Results: The review included 89 articles exploring the disadvantages of traditional disinfection methods and the search for alternative sanitation strategies. The description of various solutions for the introduction of probiotic purification methods is systematized – using bacteriophages, probiotic microorganisms of R. Bacillus and representatives of lactic acid bacteria as active agents.Conclusions: A system of sanitary measures based on probiotic biodesinfectants, including lactic acid bacteria, can be included among the tools for countering pathogens, including their biofilms and forms with multidrug resistance. The introduction of a probiotic hygienic cleaning system, without having a negative impact on the environment, can increase the effectiveness of traditional hygienic preventive measures both in medical institutions and in production.

The future of preventive dentistry: Caries vaccine on the horizon

A common dental condition known as tooth decay is brought on by a combination between microbes and fermented sugars. Traditional preventive measures, such as oral hygiene practices and fluoride treatments, have proven effective in lowering the prevalence of cavities in the mouth. However, these approaches have limitations in terms of their effectiveness and accessibility. Caries vaccination has emerged as a promising approach to preventing dental caries, offering long-lasting protection against this disease. This abstract provides an overview of the prospects of caries vaccines, including their potential benefits, challenges, and limitations. While caries vaccines remain an area of active research and development, there are several promising prospects that suggest that by this approach potential cavity formation may be effectively avoided particularly. Ongoing research and evaluation of caries vaccines will be necessary to fully understand their potential benefits and risks and to develop safe and effective vaccines that can be widely used to prevent dental caries.

Antimicrobial Nanoparticles Mediated Prevention and Control of Membrane Biofouling in Water and Wastewater Treatment: Current Trends and Future Perspectives.

Global water scarcity and water pollution necessitate wastewater reclamation for further use. As an alternative to conventional techniques, membrane technology is extensively used as an advanced method for water purification and wastewater treatment due to its selectivity, permeability, and efficient removal of pollutants. However, microbial biofouling is a major threat that deteriorates membrane performance and imparts operational challenges. It is a natural phenomenon caused by the undesirable colonization of microbes on membrane surfaces. The economic penalties associated with this menace are enormous. The traditional preventive measures are dominated by biocides, toxic chemicals, cleaners and antifouling surfaces, which are costly and often cause secondary pollution. Recent focus is thus being directed to promote inputs from nanotechnology to control and mitigate this major threat. Different anti-microbial nanomaterials can be effectively used to prevent the adhesion of microbes onto the membrane surfaces and eliminate microbial biofilms, to provide an economical and eco-friendly solution to biofouling. This review addresses the formation of microbial biofilms and biofouling in membrane operations. The potential of nanocomposite membranes in alleviating this problem and the challenges in commercialization are discussed. The antifouling mechanisms are also highlighted, which are not widely elucidated.

Risky sexual practices and approaches to preventing sexually transmitted infections among urban dwelling older Yoruba men in Southwest Nigeria

Social and cultural norms and beliefs shape how men, as social actors, perceive and engage in sexual activities. Little is known about risky sexual practices and prevention strategies among older Yoruba men. As a growing concern in Nigeria, this paper explores risky sexual behaviours of older Yoruba men living in Ibadan, a metropolitan city, and their strategies for preventing sexually transmitted infections in old age. We held six focus groups and nine semi-structured interviews, with a total of 65 participants. The findings show that social norms allow older men to engage in multiple sexual relationships, which exposes them to sexually transmitted infections (STIs), and to use potent traditional medical protective and preventive measures to mitigate their vulnerability to sexually transmitted infections and the consequences of having sex with women under “magun.” Such measures include “magun” on men, incisions, amulets, and aseje (a traditionally prepared concoction). Additionally, the findings revealed that protective measures are against serious consequences of risky sexual behaviors, like sexual pleasures and death. The findings point to the need for more inclusive sexual health and HIV campaigns and strategies addressing the sexual health challenges of all men and women and must be culturally sensitive.

Traditional healers’ roles, and the challenges they face in the prevention and control of local disease outbreaks and pandemics: The case of the East Gojjam Zone in northwestern Ethiopia

ObjectivesThe main objective of this study was to assess the roles of traditional healers and the challenges they face in the of prevention and control of both local disease outbreaks and the COVID-19 pandemic, with a special emphasis on the work of traditional healers and healing centers in the East Gojjam Zone in northwestern Ethiopia, between 2020 and 2021.MethodsFrom 25 February 2021 to 2 May 2021, a mixed-methods study (qualitative techniques combined with a quantitative approach) was carried out. The study was conducted by traditional healers and at healing centers in the East Gojjam Zone. The quantitative sample size was calculated based on the assumption of a single population proportion formula. As part of the qualitative research, levels of data saturation were continuously monitored, and were used to determine what the maximum number of study participants should be. Traditional healers and their clients were the study units for the quantitative component, whereas traditional healthcare providers (of all types) and religious leaders were purposively selected as the study units for the qualitative part. Descriptive and inferential statistical methods of analysis, and narrative- and content-wise methods of analysis, were used for the quantitative and qualitative components of this study, respectively.ResultsThe quantitative findings of this study showed that 64.27% of respondents (95% CI 59.53% to 68.74%) had a good awareness of regional disease outbreaks and of the COVID-19 pandemic. Only 9.59% of people had a positive opinion regarding local disease outbreaks, the COVID-19 pandemic, and the preventive and control measures that were employed in response to these (95% CI 7.11% to 12.83%). In addition, this study revealed that a small percentage of participants (i.e., 2.16%) used traditional control and preventive measures in response to the COVID-19 pandemic and local disease outbreaks.ConclusionLess than one-tenth of respondents had a favorable attitude toward local disease outbreaks, the current COVID-19 pandemic, and the preventive and control measures that were employed in response to these. In addition, only a small number of study participants had actually used conventional control and preventive measures in response to local disease outbreaks and the COVID-19 pandemic. Nearly two-thirds of respondents had a good understanding of the preventive and control measures that were employed in response to local disease outbreaks and the COVID-19 pandemic.

A meta-analysis of the mastitis vaccination efficacy in dairy cattle.

Mastitis is the most important disease in dairy cattle with impact in welfare of animals and the economy of the dairy farming activity. Attempts have been made to produce vaccines to prevent the disease, however, results have been dubious. The aim of this study was to evaluate the efficacy of the mastitis vaccination in dairy cattle by merging several trials to allow evidence synthesis. A list of publications with common methodological grounds was selected to allow a quantitative comparison in a meta-analysis with moderators. A mixed methods model (p < 0.001), with four significant moderators was successfully fitted: "year of publication" (p < 0.001), "vaccination timing" (p < 0.01), "type of animal" (p < 0.001), and "vaccine fabrication" (p < 0.001). The model is homogeneous (p > 0.05), with the moderators explaining the variability. Efficacy decreases over time. Vaccines applied after calving show inefficacy [log risk ratio (RR) 1.72 (1.34, 2.21)], and applied before calving show reduced efficacy [log RR 0.86 (0.72, 1.03)]. Commercial vaccines don't show efficacy [log RR 1.07 (0.94, 1.22)]. Self-fabricated vaccines show efficacy [log RR (0.51, 0.94)]. Full clarification of efficacy is not shown; however, if vaccination is used, must follow a pre-calving protocol. While not showing efficacy, the vaccination has demonstrated a reduction of the severity in clinical cases, rate of culling, and has increased the production of milk and milk solids. Vaccination may improve health and welfare but does not prevent the disease effectively; it must be seen as an additional tool to the traditional preventive measures.

This Month in Anesthesiology

This Month in Anesthesiology

P214 PROGNOSTIC IMPACT OF RESIDUAL INFLAMMATORY RISK AFTER ACUTE CORONARY SYNDROME

Abstract Background Recent randomized clinical trials have shown that an anti–inflammatory treatment may reduce the recurrence of cardiovascular events in association with traditional secondary prevention measures. Aim: The aim of this observational retrospective study based on patients with acute coronary syndrome (ACS), treated with high intensity statins and undergoing an early invasive strategy, was to evaluate the incidence of residual inflammatory risk after 1 month, its possible determinants and its association with the medium–long term prognosis. Methods We selected patients with ACS without ST segment elevation (ACS–NSTEMI) admitted to our hospital from June 2015 to June 2018 who had a complete biochemical examination at 1 month after the acute event. All these patients were included in the PRATO–ACS Registry (ClinicalTrials.gov ID: NCT04087200). All–cause mortality was analyzed within 3 years. Residual inflammatory risk (RIR) was defined as 1–month high sensitivity C reactive protein (hs–CRP) value &amp;gt; 2 mg/l. The association between 1–month hs–CRP and 3–year all–cause mortality was expressed by hazard ratio (HR) and 95% confidence interval (CI). Results The study group consisted of 739 patients (mean age 68 ± 12 years, male 68.3%, mean hospital stay 5 ± 2 days) all treated with high intensity statins (rosuvastatin 20–40 mg or atorvastatin 40–80 mg) immediately upon admission and scheduled for early invasive strategy (74.5% underwent PCI). At baseline 525 patients (71%) had hs–CRP values ≥ 2 mg/l and 568 (77%) LDL cholesterol levels &amp;gt; 100 mg/dl. The incidence of RIR was 58.7%, with no significant differences between patients with LDL &amp;lt;or&amp;gt; 70 mg/dl. Lipid profile (LDL &amp;gt; 100 mg/dl, HDL &amp;lt; 40mg/dl in man and &amp;lt; 50mg/dl in woman), hs–CRP &amp;gt; 2 mg/l, the left ventricular ejection fraction &amp;lt; 40% and glomerular filtration rate &amp;lt;60 ml/min/m2 were independently associated with RIR. Multivariate analysis showed that RIR was an independent predictor of 3–year all–cause mortality (HR = 2.15 (95% CI 1.06–4.33; p = 0.03)) while LDL cholesterol &amp;gt; 70 mg/dl did not (HR = 0.98 95% (CI 0.50–1.91; p = 0.9)). Conclusions In a population of ACS patients treated with high intensity statins and an early invasive therapeutic strategy, the incidence of RIR (hs–CRP ≥ 2 mg/l) at 1 month after ACS is high (58.7%). The RIR is associated with a higher baseline clinical risk profile and was an independent predictor of 3 year all–cause mortality regardless of achieved LDL values.

A bundle of infection control measures reduces postoperative sternal wound infection due to Staphylococcus aureus but not Gram-negative bacteria: a retrospective analysis of 6903 patient episodes

Prevention of cardiac surgical site infection has largely focused on reducing infection due to Staphylococcus aureus, although other bacteria also play an important role in this complication. To assess the impact of an evolving infection control programme on the incidence of sternal wound infection (SWI), and the changing incidence of non-staphylococcal infections. A retrospective cohort study of all patients who underwent primary sternotomy at a single UK centre between September 2010 and May 2018 was undertaken. Data were collated from the 2 years preceding the stepwise introduction of a broad-ranging infection control programme, including S. aureus decolonization. In total, 6903 primary sternotomies were performed, of which 2.6% (N=178) were complicated by SWI. Gram-negative bacteria (GNB) and S. aureus were most commonly identified as causative pathogens (45.5% and 30.3%, respectively). Following programme introduction, there was a reduction in the rate of SWI from 3.9 to 1.8 cases/100 patients/month. This was mainly due to a sustained reduction in cases of S. aureus infection, with no discernible impact on GNB. Multi-variable logistic regression analysis identified coronary artery bypass grafting, procedural urgency, and procedures performed in the third quarter of the calendar year (July to September) as independent risk factors for postoperative infection. A multi-faceted infection control programme was successful at reducing the rate of SWI, primarily due to a reduction in S. aureus infections. GNB also play an important role in SWI, and traditional preventative measures fail to address these. Future intervention and impact assessments should consider GNB infections when measuring effectiveness.

Year-end academic review of 2021: Advances in the field of birth defect prevention and control in China as of 2021

Year-end academic review of 2021: Advances in the field of birth defect prevention and control in China as of 2021

IV: Glimpses from villages in the Northeast: Traditional quarantine measures came alive during the COVID-19 pandemic

During the COVID-19 pandemic, communities in the hills of Northeast India fought the epidemic by taking recourse to traditional preventive health measures, both sealing off villages and quarantining to combat the spread of the highly infectious coronavirus. These traditional emergency health measures grew out of local experience with disease but resemble the current practices of lockdown and quarantine. Quarantine measures, dismissed by the World Health Organization in 2018 as ‘no longer efficient’, were re-established in the course of the epidemic. However, these practices continued to be part of the oral tradition of villages in the Northeast and highlighted an aspect of their autonomy in this arena.

Importance of humidity and temperature in breech strike of Merino sheep

Context Breech strike is a serious disease particularly in wool sheep. Skin wrinkle and dags are known predisposing factors for breech strike, although a large part of the variation between sheep is unexplained. Aims We used sensor buttons to determine whether there were differences in humidity and temperature in the breech area of Merino sheep exposed to blowflies without traditional preventive measures being used in the flock. Methods Sixty-two Merino rams and 62 Merino ewes that had high or low breeding values for breech strike were each fitted with a sensor button to record hourly temperature and humidity in the breech over 49 days. The sensors were fitted before the onset of the blowfly season. The sensor was tied to a wool staple close to the skin in the breech and was removed when a sheep was struck. All remaining buttons were removed prior to shearing. Breech wrinkle, neck wrinkle, breech cover and faecal soiling (dags) were recorded on all the sheep. A total of 98 213 hourly temperature and humidity records were analysed with cubic smoothing splines to assess how humidity and temperature differed between struck and unstruck sheep, and whether the breech indicator traits affect temperature and humidity in the breech. Results Time of day and day-to-day variation prior to being struck explained most of the variation of temperature and humidity in the breech of the sheep. Humidity and temperature increased with an increase in breech cover. The humidity in the breech area was, on average, 2% higher in struck sheep prior to being struck. There was a sharp increase in humidity in struck sheep in the 8 days leading up to detection of breech strike relative to unstruck animals, most probably due to exudate from the wound. Conclusions Sheep prone to be struck have higher humidity in the breech than sheep less prone to be struck. Implications Temperature in the breech does not qualify as a potential indicator trait for breech strike in wool sheep, whereas humidity needs further research to determine its effectiveness as a potential indicator trait.

Clinical evaluation of complex treatment and prevention of generalized periodontitis in patients with type I diabetes mellitus with cardiomyopathy

Annotation. Diabetes mellitus is an acute problem, as evidenced by the large number of people suffering from this disease, and the tendency to significantly increase the incidence rate. The most serious complications of diabetes include cardiomyopathy, the pathogenetic aspects of which are being actively studied. Widespread inflammatory-dystrophic periodontal disease and an increase in the proportion of generalized periodontitis in patients with diabetes mellitus complicated by cardiomyopathy, makes the problem of effective treatment and prevention of this pathology among the most relevant. The purpose of the study: clinical evaluation of complex treatment and prevention of generalized periodontitis in patients with type I diabetes mellitus with cardiomyopathy according to the developed algorithm. Comprehensive treatment and prevention measures were performed in 127 patients with generalized periodontitis on the background of type I diabetes mellitus with cardiomyopathy, of which 82 patients were the main group, where treatment was carried out using our proposed treatment and prevention algorithm. The control group, in which treatment was carried out according to protocol methods, consisted of 45 patients. Clinical visual examination and determination of paraclinical indices were performed on day 30 after treatment. Statistical calculation of digital values was performed on a Pentium II computer using the statistical software package “Statgraphic 2.3” and “Microsoft Excel 2000”, the significance of changes was evaluated by t-test. As a result of the research it was found that on average, 30 days after treatment, in the main group where we used the proposed pharmacotherapy, “normalization” of periodontal tissues was studied in 26.83 % of patients, “improvement” – in 30.49 % of patients’ treatment was ineffective in 42.68 % of patients, with a reliability of p&gt;0.05. In patients of the control group, where traditional treatment and prevention measures were used to treat generalized periodontitis, on average, “normalization” of periodontal tissue was recorded in 17.78 % of patients, “improvement” of periodontal tissue was found in 28.89 % of patients. Treatment was ineffective in 53.33 % of patients. Thus, as a result of research, it can be argued that in patients with generalized periodontitis on the background of type I diabetes mellitus complicated by cardiomyopathy, whose treatment was carried out using our treatment and prevention algorithm, which included local measures and general appointments, significantly improved periodontal tissues, as confirmed by clinical observation. In the control group, where traditional treatment regimens were used, the treatment of generalized periodontitis was ineffective. In further studies, it is planned to study the microbiome of the oral cavity in patients with generalized periodontitis on the background of type I diabetes mellitus complicated by cardiomyopathy.

Influence of motor activity on indicators of physical state of student youth

The article describes the influence of motor activity on the physical condition of student youth. It is established that there is a tendency to decrease motor activity among modern youth. The positive effect of physical activity on physical fitness, health and psycho- emotional state has been studied. The importance of motivation for physical education classes and increase of motor activity is revealed. It was found that one of the valeological factors that contributes to the formation of the foundations of health and longevity of modern youth is physical activity; Excessive educational workload in higher education institutions has a negative impact on the process of students' recovery. In order to determine the level of physical health of student youth and motivation of physical education classes, a questionnaire and research were conducted according to the method of O. Pirogova. Harmonious development of personality provides adequate motor activity and cultural and aesthetic activities. Students of pedagogical specialties are not able to fully organize their motor activity. This is due to a fairly large mental load, low motivation to engage in physical education, non- adherence to a healthy lifestyle and insufficient efficiency of modern organization of physical education of students.&#x0D; One of the most common reasons is the deterioration of the diet, reduced efficiency of traditional preventive measures, reduced physical activity due to the rapid development of information and communication technologies.