ABSTRACT The introductory paper sets the stage for the research essays in the special issue. It provides an overview of the concepts of minilateralism and the context in which minilateralism has become an alternative form of collective action by states in the international arena, in particular in the Indo-Pacific region that has emerged as the new centre of gravity in world politics. How has minilateralism become a prominent feature of inter-state cooperation in the early twenty-first century, and how is it often used to complement (and in some cases, even substitute for) traditional international organisations, which are based on more liberal and inclusive multilateral norms and principles, but suffering from functional deficits? In a world of more diffuse power, how can minilateralism offer states an expanded toolset for pursuing their policy preferences and advancing their interests? At the same time, the paper also highlights the potential negatives of (or challenges to) minilateralism, including difficulties emanating from a narrowly framed agenda that perpetuates certain narratives, a leadership vacuum that could emerge from non-hierarchical arrangements, and questions about how to achieve support and legitimacy with low institutionalisation.