To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes. Multicenter, randomized clinical trial. University teaching hospitals. Women aged >18years with suspected endometriosis who elected to undergo surgical management. Randomization to conventional or robot-assisted laparoscopic removal of endometriosis. The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life. The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 ± 48.4minutes vs. 101.6 ± 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6weeks and 6months. There were no differences in perioperative outcomes between robotic and conventional laparoscopy. NCT01556204.