The United Kingdom has declared a climate change policy of 100% reduction in carbon dioxide emissions by 2050. Efforts thus far have been limited solely to electricity generation methods. While progress has been admirable, effort now must be directed at the nation’s non-electrical energy use. Nuclear energy is an essential part of any energy future, since it is low-carbon, firm and supplies synchronous electricity; however the nation’s nuclear strategy to date has been erratic, costly and lacking in strategic oversight. A multitude of reactor designs are on offer for potential uptake, and decision-makers must have clarity of vision on what these systems must deliver before forming a strategy. Choosing between these systems, given the uncharted energy future faced by the UK is a daunting prospect. Generic feasibility assessment offers a tool for decision-makers to assist them in selecting the most suitable nuclear system for chosen future conditions. Generic feasibility assessment offers an alternative to traditional multi-attribute decision analyses, which can be confusing to even committed stakeholders when large numbers of attributes are weighted and compiled. Generic feasibility assessment forms part of a toolkit which will be of utility in achieving net zero by 2050, given the short time that remains.