Tract Infection In Neonates Research Articles

Suprapubic Aspiration of Urine in Very Low Birth Weight Infants

The incidence of urinary tract infection in the neonatal period is higher in preterm than in term infants.1 These are typically late-onset infections occurring after 72 hours of age.2 Because the signs of urinary tract infection in neonates are nonspecific, a safe and effective way of sampling urine for culture such as suprapubic aspiration is essential. Although previous studies have demonstrated the efficacy of this procedure in term and preterm infants, the preterm infants studied previously were undoubtedly larger than those very low birth weight infants cared for in today's neonatal intensive care units, inasmuch as survival rates for these small infants have increased.1,3

Antifungal and antiviral activities of benanomicins and their analogues.

In vitro activities of benanomicins and their analogues against human immunodeficiency virus and fungi including Candida, Cryptococcus and Aspergillus, were examined. The free carboxyl group and at least one sugar moiety in the benanomicins were essential for their activities. Benanomicin A was most active and had low toxicity, and was selected as the best candidate for chemotherapy.

The prevalence of bacteriuria among high risk neonates in Nigeria.

Among the 446 high risk neonates studied for significant bacteriuria and pyuria in the neonatal wards of the Obafemi Awolowo University teaching hospital Complex, Ile-Ife, 7.6% and 5.8% were positive for significant bacteriuria and pyuria respectively, while none of the 81 infants in the control group were positive. Males and females were similarly affected and there was no seasonal variation in the prevalence of pyuria or bacteriuria. It is noteworthy that 25 (96%) of the 26 pyuria neonates also had bacteriuria emphazising the significance of pyuria as a possible screening method for urinary tract infections in neonates. The clinical problems in the neonates studied included prematurity, low birthweight, neonatal jaundice, fever, CNS symptoms, ophthalmia neonatorum, prolonged rupture of the membranes (PROM), respiratory distress, septic cord/skin, diarrhoea, vomiting and feeding problems. Only prematurity and low birthweight were significantly associated with bacteriuria in the neonates studied. The organisms encountered in this study were Escherichia coli (58.4%), Klebsiella species (35.3%) and Proteus species (5.9%). Of the bacterial isolates, 67% were sensitive to Ampicillin and 97% to Gentamycin. The combination of these antibiotics was effective in all cases in the present study. The study has highlighted the need for routine urine culture in our high risk neonates.

Trichomonas vaginalis urinary tract infection in an infant.

Trichomonas vaginalis is rarely associated with urinary tract infections in neonates. In the few cases reported T. vaginalis was present simultaneously with bacterial agents. We report an infant in whom T. vaginalis was identified as the sole pathogen.

Bladder emptying in neonates.

Ultrasound scanning was used to determine whether bladder emptying is complete when a newborn baby micturates. Residual urine was detected in 6 females and 9 males while one female emptied her bladder completely. The residual volume was estimated in 11 subjects and ranged from 3.9 to 13.9 ml. Incomplete bladder emptying cannot be the main factor in explaining the sex incidence of urinary tract infection in neonates.

Urinary Tract Bacterial Infections: Office Diagnosis and Management

The incidence, clinical features, diagnostic methods, bacteriology, and management of urinary tract infection in neonates and children are presented.