Trace Metals In Environment Research Articles

Determination of trace metals in aqueous environments by anodic stripping voltammetry with a vitreous carbon rotating electrode.

Determination of trace metals in aqueous environments by anodic stripping voltammetry with a vitreous carbon rotating electrode.

Production of arterial hypertension by cadmium in the dog.

Abstract This investigation was undertaken to determine whether or not systemic arterial hypertension could be induced in the dog by cadmium, an environmental trace metal implicated in the pathophysiology of human hypertension. Eight adult healthy female mongrel dogs were given 24 intraperitoneal injection of cadmium acetate, 2 mg. per kilogram body weight over a 9 month period. Systemic blood pressure, heart rate, cardiac output, systemic vascular resistance, in vivo magnification selective renal arteriography and regional distribution of renal blood flow, and detailed hematologic and biochemical studies were serially performed. It was found that there was no mortality or significant morbidity or changes in the total body weights of the cadmium-treated dogs. Except for the decreased creatinine clearance in the cadmium-treated dogs, there were no significant abnormalities detected in the hematologic and biochemical monitoring of the renal, hepatic, and cardiac systems, and mineral metabolism. The average mean arterial pressure was significantly elevated (P