Abstract The toxicity of six fumigants—methyl bromide, ethylene dibromide, ethylene oxide, hydrogen cyanide, hydrogen phosphide and carbon tetrachloride to S. granarius was determined in atmospheres containing 0, 1, 3, 20·9 and 100 per cent oxygen. Toxicity was generally increased with decreasing oxygen concentration until the latter was reduced to 1 per cent. In an atmosphere of nitrogen, where no oxygen was present, toxicity was reduced by varying degrees depending on the fumigant; with hydrogen phosphide the insects could not be killed by any concentration of fumigant applied to them in the absence of oxygen. Carbon tetrachloride was most toxic in 20·9 per cent oxygen and below this concentration toxicity was reduced as oxygen was depleted. Tribolium confusum Du V. was found to differ from S. granarius because, in the absence of oxygen, the toxicity of methyl bromide was not reduced.
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