Total Exercise Research Articles

The Effects of Resistance Training With and Without Electrical Muscle Stimulation on Body Composition of Obese Women

Background and Purpose: Nowadays, total body resistance exercise has been added to instability training and has become popular for improving health and sports performance. Resistance training is a beneficial way to improve body composition and increase muscle strength. This study aims to evaluate the effect of suspension training (total resistance exercises [TRX]) with and without electrical muscle stimulation (EMS) on body composition and muscle strength in obese women. Materials and Methods: This quasi-experimental research is an applied study in terms of research goal. A total of 36 Class 1 obese women (mean±SD age: 30.9±5.3 years, mean±SD body mass: 95.4±9.4 kg, mean±SD height: 168.2±7.8 cm) were randomly selected from qualified volunteers and grouped randomly into three groups (n=12 for each group): EMS, TRX, and TRX-EMS. The TRX group performed 8 weeks of suspension resistance training (3 sessions per week), and the TRX-EMS group performed the TRX exercises wearing a whole-body suit that provided electrical stimulation. EMS intervention includes 3 applications of 90 min/3 days per week for 8 weeks. Data were analyzed by analysis of covariance at a significance level of 0.05 using SPSS software. Results: Findings of this study demonstrate significant differences in body composition measurements among three groups after 8 weeks of interventions (P≤0.05). All three interventions increased muscle strength after 8 weeks. TRX+EMS was the most effective intervention on body composition measures (-4.3% in body mass index [BMI], -7.2% in body fat mass [BFM], and +3.6% in skeletal muscle mass [SMM]) and muscle strength (21.93% in BP-1RM and 27.4% in LP-1RM). Also, these findings may indicate that EMS was the least effective intervention on body composition and muscle strength compared with the TRX and TRX-EMS. Conclusion: According to these results, it is suggested that obese women use EMS with suspension training to lose weight and improve body composition and strength.

Postmanopozal kadınlarda osteoporoz bilgi düzeyi ve ilişkili faktörler

Objective: The aim of this study was to determine the knowledge of osteoporosis and related factors in postmenopausal women. Materials and Methods: The study was conducted with 326 postmenopausal women. A questionnaire, including Osteoporosis Knowledge Test and questions related with sociodemographic data, variables like chronic disease history, alcohol and cigarette smoking habits, gynecological-obstetric history, was applied by researchers with face to face interview to all of the participants. Results: The mean age of the participants was 59.0±10.1 years. Mean total knowledge score was 15.4±4.9; mean osteoporosis exercise knowledge score was 9.5±3.5 and mean osteoporosis calcium knowledge score was 10.6±3.3. It was found that mean total osteoporosis knowledge score, exercise and calcium knowledge scores was significantly high in participants with high educational level, non smokers. Similarly, the mean of these three scores was found to be significantly higher in participants with a history of abortion and corticosteroid use for more than 3 months. Osteoporosis knowledge score was significantly increased with menarche and menopause age. Conclusion: In conclusion, it was thought that the knowledge of osteoporosis in postmenopausal women is not sufficient, and it will be beneficial to protect and improve public health by identifying groups that may have low level of knowledge and providing health education. Keywords: Osteoporosis, menopause, level of knowledge

Implication of the Central Nucleus of the Amygdala in Cardiovascular Regulation and Limiting Maximum Exercise Performance During High-intensity Exercise in Rats

To date, the mechanism of central fatigue during high-intensity exercise has remained unclear. Here we elucidate the central mechanisms of cardiovascular regulation during high-intensity exercise with a focus on the hypothesis that amygdala activation acts to limit maximum exercise performance. In the first of three experiments, we probed the involvement of the central nucleus of the amygdala (CeA) in such regulation. Wistar rats were subjected to a maximum exercise test and their total running time and cardiovascular responses were compared before and after bilateral CeA lesions. Next, probing the role of central pathways, we tested whether high-intensity exercise activated neurons in CeA and/or the hypothalamic paraventricular nucleus (PVN) that project to the nucleus tractus solitarius (NTS). Finally, to understand the potential autonomic mechanisms affecting maximum exercise performance, we measured the cardiovascular responses in anesthetized rats to electrical microstimulation of the CeA, PVN, or both. We have found that (1) CeA lesions resulted in an increase in the total exercise time and the time at which an abrupt increase in arterial pressure appeared, indicating an apparent suppression of fatigue. (2) We confirmed that high-intensity exercise activated both the PVN-NTS and CeA-NTS pathways. Moreover, we discovered that (3) while stimulation of the CeA or PVN alone both induced pressor responses, their simultaneous stimulation also increased muscle vascular resistance. These results are evidence that cardiovascular responses during high-intensity exercise are affected by CeA activation, which acts to limit maximum exercise performance, and may implicate autonomic control modulating the PVN-NTS pathway via the CeA.

540-P: Meta-analysis of Blood Glucose Response to High Intensity Exercise in Adults with Type 1 Diabetes

Background: High intensity exercise-induced hyperglycemia is recognized in T1D clinical guidelines, but its occurrence after high intensity intermittent exercise (HIIE) in acute studies is inconsistent. This meta-analysis aimed to examine the available evidence of BG responses to HIIE in adults with T1D. The secondary aim was to assess the role of prandial status (fasted/fed) , sex (by percentage of female participants ≤ 50, or > 50) , mean age, fitness (VO2peak) , interval duration, and total exercise duration on BG outcomes. We hypothesized that there would be no consistent effect on BG from HIIE, unless examined in the context of participant prandial status. Methods: We conducted a literature search using keywords related to T1D and HIIE. Studies were required to have a minimum of 6 participants with T1D aged ≥17 years, involving a HIIE intervention, and a pre- and post-exercise measure of BG to be included. Analyses were performed using a general inverse variance statistical method with a random effects model on RevMan5® statistical software and a weighted multiple regression on STATA17® statistical software. Results: Seventeen interventions from 13 studies were included in the final analysis. A mean overall BG change of -1.4 mmol/L (-3.0, 0.2) was found during exercise albeit with high heterogeneity (I2= 92%) . Fasted exercise increased BG by +1.7 mmol/L (-0.2, 3.6) , while fed exercise decreased BG by -2.6 mmol/L (3.7, -1.5) , with a statistically significant difference between groups (p<0.001) . There were no significant effects from sex (p=0.74) , fitness (p=0.46) , age (p=0.89) , interval duration (p=0.25) or exercise duration (p=0.38) . Conclusions: The effect of HIIE on BG is inconsistent, but partially explained by prandial status. Disclosure R.Mcclure: None. E.Weseen: None. F.Alcántara cordero: None. M.Maldaner: None. S.Hart: None. N.G.Boulé: None. J.E.Yardley: Research Support; Abbott, Dexcom, Inc., LifeScan, Speaker's Bureau; Abbott Diabetes.

Effects of Tobacco Consumption on Aerobic Fitness in Indian Adult Men

Background and Aim: Smokeless tobacco products like khaini, guthakha, betel quid, zarda are very commonly consumed by men and women of all age group followed by smoking of bidi, cigarette and hookah. Tobacco consumption is associated with poor cardiorespiratory, gastrointestinal and overall health. Compromised physical fitness is seen in tobacco consumers and severity depends on type of product and duration of use. Aerobic or cardiorespiratory fitness is compromised in tobacco consumers. This study was planned to check the effect of tobacco consumption on aerobic fitness of Indian adult men of 18 to 60 years of age group. Methods: Participants for this study were recruited from Pramukhswami Medical College and its affiliated institutes after obtaining permission from the Institutional Ethics Committee (IEC). A total 74 adult men of 18-60 years’ age groups were enrolled for the present study after their voluntary consent. A total 24 participants who consume tobacco were placed in study group and a total 50 participants who were not consuming tobacco products were placed control group. All participants were apparently healthy at the time of Treadmill exercise stress test following Bruce protocol. Predicted VO2 max (PVO2 max) was calculated on the basis of total exercise time in minutes and seconds on Treadmill machine as per Bruce’s formula of calculating indirect maximal oxygen consumption. Results: PVO2 max values obtained by Treadmill exercise test following Bruce protocol in study group was 29.16 ± 8.88 ml/kg/min while control group was 36.47 ± 9.7. A statistically significant reduction in aerobic fitness was seen in study group as compared to control group. Conclusion: Aerobic fitness was significantly less in tobacco consumer Indian adult men of 18-60 years’ age group as compared to who do not consume tobacco.

Effect of Surgical Mask use on Peak Physical Performance During Exercise Treadmill Testing-A Real World, Crossover Study.

Background: Mask wearing is an essential strategy to combat the spread of SARS-CoV-2. Some individuals may wear masks during physical activity to reduce disease transmission. This study aimed to investigate the real-world effect of wearing a surgical face mask on physiological parameters at peak exercise in healthy individuals. Methods: In this crossover design study, participants underwent maximal treadmill electrocardiogram exercise tests using the Bruce protocol on two separate occasions, once with a standard 3-ply surgical face mask and once without. Heart rate, oxygen saturation, blood pressure, rate pressure product, metabolic equivalents (METS) and total exercise time were measured. Subjective rate of perceived exertion was also assessed using the modified Borg Scale. Results: 50 adults (mean age = 31.7 ± 6.5 years; 27 males) completed both treadmill tests. Mask wearing resulted in a significant reduction in peak METS by 1.5 units, maximum speed by 0.5 km/h, exercise time by 68.4 s with a significantly lower peak heart rate by 4.4 bpm, and lower percentage of age-predicted maximum heart rate by 2.5% (p < 0.001 for all parameters). During each corresponding stage of the Bruce protocol, the average modified Borg score was found to be significantly higher in subjects exercising with mask after adjusting for age, gender and body mass index (p < 0.03). Conclusion: In a cohort of healthy individuals, wearing of a surgical face mask during maximal treadmill exercise lead to reduced physical performance and increased rate of perceived exertion. Individuals exercising with surgical masks need to be mindful of these limitations while undergoing physical training in order to differentiate these physiological responses from symptoms of early respiratory illness.

Comparison of the Effects of Total Body Resistance Exercise and Traditional Resistance Training on the Immune System Biomarker in Inactive Obese Women

Objective: This study aimed to compare the effect of eight weeks of traditional resistance training and total body resistance exercise (TRX) on the immune system of obese sedentary women.&#x0D; Materials and Methods: In this quasi-experimental study, 28 obese women with a mean body mass index (BMI) of 30.39± 4.65 (kg/m2) were randomly divided into three groups of TRX training (N= 9), traditional resistance training (N= 9) and control (N= 10). The experimental groups performed exercise training in three sessions per week for 8 weeks. Blood samples were taken from all subjects 48 hours before and after the last training session and were used for neutrophil, lymphocyte, monocyte, basophil, and eosinophil analysis. Data were statistically analyzed using dependent T-test and one-way analysis of variance (ANOVA) by SPSS software, the significance level was P&lt; 0.05.&#x0D; Results: The results of the study did not show significant differences within and between groups in the variables of the immune system (neutrophils, lymphocytes, monocytes, eosinophils) (P&lt; 0.05). Also, the results of ANOVA showed a significant difference in basophil count only between the three groups (P= 0.006).&#x0D; Conclusion: According to the results of the study, no significant difference in immune system indices was observed between the groups. Therefore, performing traditional resistance exercises and moderate-intensity TRX has no significant effect on the immune system of sedentary obese women.

The Effect of Amiloride (10mg) on the Blood Pressure Response to Ischemic Exercise: Preliminary Observations

BackgroundDuring exercise, blood pressure increases via augmented central command and stimulation of mechano‐ and metabosensitive muscle afferents (i.e., the exercise pressor reflex). Recent evidence has reported a strong role of acid sensing ion channels (ASIC’s) in mediating this reflex, as well as exercise induced muscle pain. Therefore, it is logical to suspect that inhibiting ASIC’s would mitigate the exaggerated blood pressure responses and exercise related muscle pain observed in individuals with peripheral artery disease (PAD).Purpose. We tested the hypothesis that a single 10mg dose of amiloride (a K+‐sparing diuretic known to inhibit ASIC’s) would attenuate the pressor response to blood flow restricted (BFR) plantar flexion exercise in young healthy adults.MethodsSix healthy subjects (5 male, 26 ± 2 y/o, 180.8 ± 12.1 cm, 79.7 ± 12.9 Kg) completed three separate visits. Each visit included two bouts of isometric plantar flexion, both performed until failure at 30% of the predetermined maximal voluntary isometric contraction. During one bout, blood flow to the limb was restricted via a pressurized cuff placed around the proximal portion of the lower leg (BFR); the other bout was performed under free flow conditions. In the first visit, subjects performed these two exercise bouts (in random order) under normal, non‐treated conditions. In the second and third visits, subjects performed these exercise bouts (same order as in visit 1) ~3 hrs after oral ingestion of 10mg of amiloride, or ingestion of a placebo (random order). Blood pressure and heart rate were continuously recorded throughout exercise, and time to fatigue and muscle pain (on a 12cm visual analog scale) was recorded at the end of each exercise bout. Only data from the placebo and amiloride conditions are presented here.ResultsThe addition of BFR reduced total exercise time by ~40.8% (t=2.99, p=0.03), but had no significant effect on peak muscle pain (p&gt;0.10). Due to the preliminary nature of these data, no significant main effects of treatment (amiloride vs. placebo) were observed for free flow or BFR exercise (all p&gt;0.05). However, we did observe a net decrease in the average heart rate response (+10.7 ± 3.0 bpm vs. +11.3 ± 3.7 bpm, ηp2=0.539, p&gt;0.47), the total blood pressure response (5477.5 ± 373.7 mmHg*sec vs. 5841.3 ± 518.9 mmHg*sec, ηp2=0.250, p&gt;0.30), the total time‐tension index (595.9 ± 406.5 Kg*sec vs. 691.6 ± 394.2 Kg*sec, ηp2=0.211, p&gt;0.30), and the blood pressure to time‐tension index relationship (9.09 ± 4.40 mmHg/Kg vs. 11.38 ± 6.30 mmHg/Kg, ηp2=0.08, p&gt;0.50) in the amiloride condition compared to the placebo condition during BFR exercise.ConclusionsWhile these preliminary findings do not indicate significant effects of treatment, these observations serve as strong pilot data to support the continued investigation of amiloride as a method of attenuating the pressor response to ischemic exercise.

The Korean-Lung Information Needs Questionnaire: Translation, validation and clinical implications in comprehensive pulmonary rehabilitation.

PurposeChronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and persistent respiratory symptoms. Several symptom‐related questionnaires have been validated to improve understanding for patient with COPD. We aimed to systematically translate the English version of the Lung Information Needs Questionnaire (LINQ) into Korean and to verify the reliability, validity and clinical implications in comprehensive pulmonary rehabilitation (PR).MethodsThe original version of LINQ was translated into Korean by two translators and reviewed by the translation committee. It was then reverse translated back into English. The committee compared the reconciled version in Korean and the original version in English. A cognitive debriefing was performed on the pre‐final version, and a final version, K‐LINQ, was obtained. A test‐retest method for the analysis of reliability was performed within 2 weeks. Concurrent validity analysis was performed using Pearson correlation test of the K‐LINQ and other evaluation tools.ResultsA total of 110 patients were enrolled. The length, readability, understanding and suitability of the questionnaire rated well in scores for face validity of 52 Korean patients with COPD. No significant correlation was derived from the total K‐LINQ and each domain with other scales such as mMRC, K‐CAT and K‐LCADL. The intra‐class correlation coefficient of total score K‐LINQ showed high reliability. Patients who attended PR showed significantly poor pulmonary function or more severe symptoms. In addition, a significantly lower score in total score and exercise domain of K‐LINQ were confirmed in the group of PR attendees.ConclusionsWe translated the LINQ into Korean, implemented cross‐cultural adaptation and verified its validity and reliability. K‐LINQ can now be useful in various clinical and research fields in the Republic of Korea and could serve a complementary role and become an axis of successful treatment strategies, including a comprehensive PR programme.

Efficacy of INtensive Treatment vs. Standard Treatment of COmpound DanshEn Dripping Pills in Refractory Angina Patients With Incomplete Revascularization (INCODER Study): Study Protocol for a Multicenter, Double-Blind, Randomized Controlled, Superiority Trial.

IntroductionPatients with incomplete revascularization (ICR) tend to develop refractory angina despite optimal medical therapy. The Compound Danshen Dripping Pills (CDDP) is a widely used antianginal drug in China and is shown to significantly alleviate myocardial ischemia. Previous studies showed dose-efficacy tendency when increasing doses of CDDP. This study aims to investigate the efficacy and safety of intensive doses of CDDP in patients with refractory angina with ICR.Methods and AnalysisThe INCODER study is a multicenter, double-blind, randomized controlled, superiority trial. We plan to recruit 250 patients aged 18–85 years with a diagnosis of refractory angina with ICR. Patients will be randomized (1:1) to intensive treatment group (CDDP 20 pills three times per day) or standard treatment group (10 pills CDDP and 10 pills placebo three times per day). Patients will have a 6-week medication period and be followed up every 2 weeks. The primary endpoint is the change of total exercise time from baseline to week 6 as assessed by cardiopulmonary exercise testing (CPET). Secondary endpoints include changes in the frequency of angina, Canadian Cardiovascular Society angina class, nitroglycerin use, Seattle Angina Questionnaire scores, peak oxygen uptake (VO2 peak) and other parameters as measured by CPET, and the levels of plasma C-reactive protein, homocysteine, and N-terminal pro-B-type natriuretic peptide. Safety events related to CDDP use will be monitored.Ethics and DisseminationThe research had been approved by the Clinical research and laboratory animal ethics committee of the First Affiliated Hospital, Sun Yat-sen University ([2019]65). The results will be reported through peer-reviewed journals, seminars, and conference presentations.Trial Registration Numberwww.chictr.org.cn (ChiCTR2000032384). Registered on 27 April 2020.

Daily physical activity measured by a wearable activity monitoring device in patients with rheumatoid arthritis.

Activities of daily living in patients with rheumatoid arthritis (RA) have been evaluated by patient-reported outcomes. However, it has been difficult to measure activity intensity quantitively. Calories expended, exercise, and steps were measured quantitively by a wearable activity meter, and their associations with patients' background characteristics were examined. Data from a prospective, observational study (CHIKARA study) were used. Eighty-five of 100 RA patients were entered and wore a wearable activity meter for 7days. The daily calories expended and exercise for both walking and housework and steps were evaluated. Total daily calories expended and exercise was defined as the sum of walking and housework. The relationships of DAS28-ESR, mHAQ, body composition, muscle function, and general status were analyzed. The median age was 66.0years, and the disease duration was 5.3years. DAS28-ESR was 3.11, and mHAQ was 0.125. Total daily calories expended, exercise, and number of steps were 461.7kcal, 3.97 METsh, and 4,788, respectively. MHAQ, walking speed, power, locomotive syndrome, and frailty were independently related to exercise. Total daily exercise and steps of the moderate and high disease activity group were significantly lower than those of the remission group. When the number of steps was < 3,333 and < 2,468, the odds ratios for locomotive syndrome and frailty increased 14.4-fold and 8.7-fold, respectively, using Fisher's exact test (P < 0.001). Daily physical activity and number of steps were significantly decreased in RA patients with moderate and high disease activity as measured by a wearable activity meter. Key Points • Total daily calories expended and exercise for both walking and housework and steps in patients with rheumatoid arthritis were 461.7 kcal, 3.97 METs h, and 4,788, respectively, using a wearable activity meter. • Daily physical activity, especially total daily exercise and number of steps, was significantly decreased in RA patients with moderate and high disease activity. • When total daily steps were < 3,333 and < 2,468, the odds ratios for locomotive syndrome and frailty increased 14.4-fold and 8.7-fold, respectively.

The THE COMPARISON OF PLYOMETRIC AND RESISTANCE WARMUP PROTOCOLS ON THE RUNNING PERFORMANCE IN RECREATIONAL ATHLETES

Background: Warm-up prepares the body to withstand the high-intensity exercises and improves the athletic performance and reduces the risk of musculoskeletal injury. Active warm-up is one of the best and commonly used techniques in athletes that can induce a special type of cardiovascular and metabolic changes that can bring prominent change in running performance. Objective: To compare resistance and plyometric warm up Protocols in recreational athletes to improve running performance. Methods: A randomized clinical trial was conducted at Aman Medical Institute Islamabad. A total n=33 recreational athletes of both genders, having total exercise load less than 5 hours per week, with normal BMI and Must fulfill the 10 minutes’ walk test on treadmill before starting the warm-up were recruited through convenience sampling technique. The sample was randomly assigned through sealed envelope method into Resistance warm up protocol (n=11), plyometric warm up protocol(n=11) and control group(n=11). The running performance was measured with lower limb power, VO2max, endurance, fatigue and time of exhaustion. The RCT was registered in national library of medicine. Data was analyzed on SPSS version 23. After checking the normality, kruskal walis test was applied to compare the groups. Results: The mean age of the participants were 21.97+1.3 years and BMI were 23.27+1.12 kg/m2. There was significant improvement in plyometric group in terms of VO2max (p=0.003), rate of perceived exertion (p&lt;0.001), time of exhaustion (p&lt;0.001), fatigue (p=0.002), power p=(.002), endurance (p&lt;0.001) as compared to other groups. Conclusion: It is concluded that there was improvement in running performance in plyometric warm up protocol and resistance warm up protocol as compared to control group Keywords: Lower limb power, Plyometric, Resistance warm up, Running performance

Impact of the COVID-19 Pandemic on Exercise Habits Among US Primary Care Patients.

To explore how the COVID-19 pandemic has affected exercise habits, we hypothesized that participants' physical activity would have increased by at least 30 min/wk after the onset of the pandemic. We distributed an anonymous survey to ambulatory patients at the Family Medicine Clinic, University of Kansas Medical Center to analyze changes in exercise habits and weight. Of the 500 adult patients surveyed, 382 were included. Results were stratified by demographics, including employment status before and during COVID-19. The median change in weekly exercise duration was 0.0 minutes, but the mean change was -25.7 minutes; total exercise duration decreased after the pandemic's onset (paired Wilcox signed rank test P < .001). More individuals reported participation in virtual group classes (6.3% before the pandemic vs 13.1% during the pandemic; McNemar's P < .001). Individuals with home exercise equipment before the pandemic were more likely to acquire more than were those who had none before (Chi square test P < .005). Overall, there is a significant trend in the direction of weight gain (Wilcox signed rank test P < .001). Most participants decreased physical activity during the unprecedented COVID-19 pandemic, expanding our understanding of how exercise habits change during stressful life events.

CHARACTERISTICS OF BODY LOAD IN PHYSICAL TRAINING FOR FOOTBALL PLAYERS

ABSTRACT Introduction: Overtraining in football is caused by an imbalance between body load, stress, and recovery. High-volume non-scientific physical training and continuous high-intensity football matches are often the main reasons for the overtraining of athletes. Objective: This article explores the characteristics of the changes in physical function of football players during a complete training cycle. Methods: We use experimental methods to analyze the changes in the physical load characteristics of football players during high-intensity training. Results: Creatine kinase, urea nitrogen, and oxygen transport indicators did not change significantly during football training. Testosterone and cortisol will gradually increase with an increase of exercise load. Conclusion: In football training, we need to reasonably arrange the total exercise volume, exercise intensity, and exercise interval time of the athletes according to the trainer’s physical adaptability and athletic ability, supplemented with nutrition and enthusiasm recovery measures. These methods can improve or enhance the physical function of football players. Level of evidence II; Therapeutic studies - investigation of treatment results.

The effect of TRX suspension trainer and BOSU platform after reconstruction of anterior cruciate ligament of the knee joint

Background and Study Aim. The tear of the anterior cruciate ligament of the knee joint is experienced by people of all ages for a variety of reasons. The physiotherapy procedures with different equipment help recover lost functions. The aim of this research was to determine the effect of ‘TRX’ (Total body Resistance eXercise) suspension trainer and platform ‘BOSU’ (Both Sides Utilized) after anterior cruciate ligament of knee joint reconstruction.&#x0D; Material and Methods. The study included 20 patients after anterior cruciate ligament reconstruction surgery, 13 women, age (31.7 ± 3.4) and 7 men, age (31.7 ± 3.5) participated in the assessment. The strength of the calf flexors and extensors muscles was assessed by Lovett scale. The range of motion of the knee joint was assessed by goniometer. The static and dynamic body balance was assessed by Fullerton Advanced Balance Scale. The stability of the knee joint was assessed by Lachman test. The statistical data reliability was evaluated using Student's T criterion.&#x0D; Results. The data obtained showed that stabilization exercises with ‘TRX’ suspension trainer ant platform ‘BOSU’ have positive effect on knee joint after reconstruction. In the first and second group strength of the calf flexors and extensors muscles, amplitude of knee joint, static and dynamic balance significantly increased (p&lt;0.05). Knee joint stability increased. Comparing both groups’ results, there are no statistically significant difference (p&gt;0.05). &#x0D; Conclusions. Physiotherapy exercises with TRX suspension trainer and platform ‘BOSU’ can help patients to return lost muscles strength, knee joint amplitude, static and dynamic balance and knee joint stability.

Effect of trimetazidine on the functional capacity of ischemic heart disease patients not suitable for revascularization: Meta-analysis of randomized controlled trials.

ObjectiveTo explore the effect of adding trimetazidine to other anti-anginal drugs on the functional capacity of ischemic heart disease (IHD) patients not suitable for revascularization when compared to first-line antianginal drugs alone.MethodsMEDLINE and EMBASE databases were searched for English-language peer-reviewed randomized controlled trials (RCTs) comparing trimetazidine with first-line antianginal drugs alone or with placebo in IHD patients not suitable for revascularization and were included in this review. Quality of studies were assessed using the Cochrane collaboration “risk of bias” tool.ResultsSix RCTs, three were crossover studies. A total of 312 participants were included in this review. Overall quality of studies was moderate. Two studies found improvement in the 6-minute walking test (6-MWT) [standardized mean differences (SMD) 1.75; 95% CI 1.35 to 2.14; p <0.001], and two trials found improvement in the Canadian cardiovascular society (CCS) grading of angina class (SMD -1.37; 95% CI -1.89 to -0.84) in the trimetazidine group. Three of the better-quality trials found no increase in total exercise duration (TED) (SMD 0.34; 95% CI -0.10 to 0.78; p < 0.13). Significant heterogeneity was identified among trials describing outcomes for the New York Heart Association (NYHA) functional classification and left ventricular ejection fraction (LVEF %).ConclusionTrimetazidine improve walking time and angina severity in IHD patients not suitable for revascularization. Due to the inconsistency of available evidence, RCTs targeting IHD patients with “no option” to undergo coronary revascularization is required to clarify this review question.

High-Intensity Interval Training for Reducing Cancer-Related Fatigue in Survivors of Cancer: Challenges and Solutions for Translation and Implementation in Cancer Rehabilitation

Moderate-intensity continuous aerobic exercise training (MICT) is used to help alleviate symptoms of cancer-related fatigue (CRF) in many cancer rehabilitation programs. High-intensity interval training (HIIT) has become increasingly popular, including several research studies demonstrating promising effects of HIIT on CRF among patients and survivors of cancer. However, we propose that 2 primary limitations exist in the current literature that must be addressed before HIIT should be translated from research studies and implemented in cancer rehabilitation. These limitations are the lack of generalizability of this research and a paucity of studies that have directly compared MICT with HIIT while matching for total exercise volume. In this commentary, we expand on the rationale for the proposed limitations and provide suggestions for future research directions.

Prospective Associations Between Physical Activity and Perceived Fatigability in Older Men: Differences by Activity Type and Baseline Marital Status.

Lower physical activity has been cross-sectionally associated with greater perceived fatigability, defined as self-reported fatigue anchored to activity intensity and duration. The temporality of this relationship, and whether it differs by activity type or marital status, remains unclear. In the Osteoporotic Fractures in Men Study (N = 1 759), self-reported total, exercise, and household activity were assessed using the Physical Activity Scale for the Elderly across 7 visits (2000-2016). The Pittsburgh Fatigability Scale (range: 0-50; higher scores = greater fatigability) measured physical (mean = 16.6 ± 9.7) and mental (mean = 7.8 ± 8.3) fatigability at Year 14. Least absolute deviation and linear regression were used to examine associations between baseline and change in activity over 14 years with subsequent fatigability. Models were adjusted for demographic, health, and lifestyle factors. After adjustment, lower baseline (β= -0.08, 95% confidence interval [CI]: -0.12, -0.04) and greater annual declines in total activity (β = -0.09, 95% CI: -0.14, -0.05) were prospectively associated with higher Pittsburgh Fatigability Scale (PFS) Physical scores. Associations were similar for mental fatigability (both p < .05). Lower baseline leisure exercise, but not baseline household activity, predicted higher PFS Physical scores (β = -0.10 vs -0.001). In contrast, greater declines in household activity, but not declines in exercise, were associated with higher PFS Physical scores (β = -0.09 vs -0.03). Lower baseline household activity predicted higher PFS Mental scores only for unmarried men (β = -0.15, 95% CI: -0.29, -0.01, interaction p = .019). Baseline total activity and leisure exercise, and declines in total and household activity, were associated with higher subsequent perceived fatigability in older men. Marital status may mitigate the contribution of household activity to subsequent fatigability.

좌업 생활 노인의 걷기 운동량에 따른 대사증후군과 대사 관련 요인 관계 분석

Purpose: The purpose of this study is to assess the influence of the amount of walking exercise on metabolic syndrome and metabolism-related factors for the elderly with sedentary life using KNHNES data.<BR> Method: The data were obtained from the KNHNES Ⅶ conducted in 2016~2108. The subjects, a total of 4,288 elderly aged 65 years and older, were classified into two groups based on habitual sedentary life time and three groups based on total walking exercise amount. The dta processor for this study was used as a percentage and standard error (SE) or mean (M) of all measured values, used chi-square test, generalized linear model, and logistic regression analysis.<BR> Results: The results of this study are as follows. 1) The body mass index and waist circumference of the sedentary life group were significantly higher than those of tehnormal group (p<.001). 2) The prevalence of metabolic syndrome was significantly higher in the sedentary lief group than in the normal group (p<.001). 3) The difference of metabolism-related factors between the walking exercise amount groups in sedentary life was significantly higher in height, weight, total calorie intake (p<.001), and HDL-C (p<.01). 4) The prevalence of metabolic syndrome in the walking exercise groups was significant (p<.05).<BR> Conclusion: In summary, the findings in this study confirm that people with a sedentary life are more likely to have metabolic syndrome. The amount of high-intensity walking exercise and the amount of moderate-intensity walking exercise in a sedentary life can prevent metabolic syndrome.

Intensive physical therapy after emergency laparotomy: Pilot phase of the Incidence of Complications following Emergency Abdominal surgery Get Exercising randomized controlled trial.

Postoperative pneumonia and delayed physical recovery are significant problems after emergency laparotomy. No randomized controlled trial has assessed the feasibility, safety, or effectiveness of intensive postoperative physical therapy in this high-risk acute population. The internal pilot phase of the Incidence of Complications after Emergency Abdominal Surgery: Get Exercising (ICEAGE) trial was a prospective, randomized controlled trial that evaluated the feasibility, safety, and clinical trial processes of providing intensive physical therapy immediately following emergency laparotomy. Fifty consecutive patients were recruited at the principal participating hospital and randomly assigned to standard-care or intensive physical therapy of twice daily coached breathing exercises for 2 days and 30 minutes of daily supervised rehabilitation over the first 5 postoperative days. Interventions were provided exactly as per protocol in 35% (78 of 221 patients) of planned treatment sessions. Main barriers to protocol delivery were physical therapist unavailability on weekends (59 of 221 patients [27%]), awaiting patient consent (18 of 99 patients [18%]), and patient fatigue (26 of 221 patients [12%]). Despite inhibitors to treatment delivery, the intervention group still received twice as many breathing exercise sessions and four times the amount of physical therapy over the first 5 postoperative days (23 minutes [interquartile range, 12-29 minutes] vs. 86 minutes [interquartile range, 53-121 minutes]; p < 0.001). One adverse event was reported from 78 rehabilitation sessions (1.3%), which resolved fully on cessation of activity without escalation of medical care. Intensive postoperative physical therapy can be delivered safely and successfully to patients in the first week after emergency laparotomy. The ICEAGE trial protocol resulted in intervention group participants receiving more coached breathing exercises and spending significantly more time physically active over the first 5 days after surgery compared with standard care. It was therefore recommended to progress into the multicenter phase of ICEAGE to definitively test the effect of intensive physical therapy to prevent pneumonia and improve physical recovery after emergency laparotomy. Therapeutic/Care Management; Level II.