BackgroundNursing is considered a difficult and stressful profession as it deals with the human aspects of health and illness, which can ultimately lead to job dissatisfaction and exhaustion. AimThe study aims to find out the levels of burnout and resilience among nurses and compare them with other variables. The study also attempts to determine the relationships between burnout and resilience of nurses. MethodsThe study used a cross-sectional design and the data was collected by utilizing a standardized questionnaire which was conducted through an electronic survey from nurses at public hospitals that were entirely or partially designated for treating COVID-19 cases. Both descriptive statistics and inferential statistics were used for data analysis. ResultsThe response rate was 92.7% to the questionnaires. The findings illustrated that 56.4% of them were female. The total mean and standard deviation scores for Maslach's Burnout Inventory were 64.8 (18.1), respectively. The resilience overall mean and standard deviation were 26.1 and (6.6). The results suggest that the work shift of nurses had a significant difference in the means compared with the total resilience at p-value p = 0.003. ConclusionsDuring the COVID-19 pandemic, nurses in Kirkuk city had a moderate level of burnout and resilience. Burnout and resilience were indicated as statistically related to the shift of working with the total resilience and hardness subscale.