Enterocolitis is evolving as a common entity in patients after surgery for T.C.A., irrespective of the surgical procedure. The syndrome is characterized by diarrhea, cachexia,and abdominal distention. We evaluated 3 childrens with this syndrome, aged 13 months, 14 months, and 6 years. Patients had evidence of marked small and large bowel dilatation on xray, confirmed on barium studies. Stool cultures were negative for all currently known enteropathogens and rotovirus. All patients had malabsorption as indicated by iron deficiency anemia, an abnormal stage 2 Schillings test, and abnormal lactose hydrogen breath test. Colitis and enteritis were documented on biopsy. Duodenal fluid cultures were negative for bacterial pathogens. Treatment: All patients were placed on hyperalimentation and total bowel rest. T.P.N. alone did not alleviate their symptoms. Metronidazole and Sulfasalizine therapy however induced remission in all 3 patients. Conclusions: Enterocolitis is common following surgery for T.C.A. 2. Malabsorption occurred in all 3 patients. 3. T.P.N., Sulfasalizine, and Metronidazole therapy resulted in remission in all 3 patients, supporting the role of bacterial overgrowth in the pathogenesis of this syndrome.