For a connected graph $$G=(V,E)$$ , two spanning trees $$T_1$$ and $$T_2$$ of G are said to be a pair of completely independent spanning trees (or a dual-CIST for short) if for any two vertices $$u,v\in V$$ , the paths joining u and v in the two trees have no common vertex except for u and v. Although the existence of a dual-CIST in the underlying graph of a network has the practical application of protection routing on fault-tolerance, it has been proved that determining whether a graph G admits a dual-CIST is NP-complete. As we know that Cayley graphs are a large family of graphs, some of its subclasses have been attracted and thus graphs in these subclasses have been adopted as the topologies of interconnection networks, such as the n-dimensional star graphs $$S_n$$ , bubble sort graphs $$BS_n$$ , pancake graph $$P_n$$ , alternating group networks $$AGN_n$$ and so on. Pai and Chang (IEEE/ACM Trans Netw 27(3): 1112–1123, 2019) recently showed that there exist dual-CISTs in $$S_n$$ , $$BS_n$$ , $$AGN_n$$ for $$n\geqslant 5$$ and provided their corresponding protection routings. So far, the problem of constructing dual-CISTs on $$P_n$$ has not been dealt with yet. In this sequel, we continue the investigation of the construction of dual-CISTs in pancake graphs as a complementary result. Since $$P_n$$ , $$S_n$$ , and $$BS_n$$ are with the same scale, we experimentally assess the performance of protection routing through simulation results for comparing them when $$n=5,6,7$$ .