We study the stability of z = 4 topological black hole in 4 + 1-dimensional Horava–Lifshitz gravity against scalar perturbations by analyzing the quasinormal modes (QNMs). It is possible to distinguish two cases for which the black hole is stable. The first one occurs when p + Q > 0 and QNMs are characterized by a real and imaginary part, meaning that the field has oscillatory modes but with Im (ω) < 0; therefore, it is stable. While in the second case p + Q < 0, QNMs are purely imaginary ( Im (ω) < 0) and then absolutely damped.