We present a comprehensive analysis of the loop induced top quark FCNC signals at the LHC within one class of the simplified model. The loop level FCNC interactions are well motivated to avoid the hierarchy of the top quark couplings from the new physics and standard model. Such a theory will posit a Majorana dark matter candidate and could be tested through dark matter relic density, direct detection experiments (the scattering between dark matter and heavy nuclei), and the collider signals at the LHC. We find that the spin-independent (SI) scattering between Majorana dark matter and nuclei will vanish at the leading order, while the next-to-leading order correction to the SI scattering becomes significant to constrain the parameter space of the model. A detailed comparison between direct detection experiments and LHC searches is also discussed and both of them are very important to fully constrain the model.