Abstract Esports and high-performance human-computer interaction are at the forefront of implementing new hardware and software technologies Despite that, there is a paucity of research on how championship-level esports professionals approach aspects of their preparation. To begin addressing this gap, we conducted, transcribed, and analyzed interviews with top-level tournament players, coaches, and managers in the period 2015–2019. The interviews focused on mental, physical, and nutritional aspects of esports preparation. Initial processing included transcription and manual verification. Furthermore, where applicable, interview responses were rated and quantified by a panel of experts. Physical training was most often mentioned as a relevant or consistent activity, while nutrition was indicated as relatively unimportant. Qualitative analysis indicated that consistency and resilience are key factors for upcoming esports competitors to focus on. Interviewees also emphasized balancing their gameplay time with other activities. Lastly, we identified important areas critical for a deeper understanding of the mental and physical demands of professional esports players.