Subject. Pulp tissue diseases are characterized by a wide prevalence, which makes it possible to consider the quality of endodontic dental treatment one of the most urgent problems of modern dentistry. High-quality treatment of complicated forms of caries is the prevention of odontogenic inflammatory processes, which include periodontitis, periostitis, osteomyelitis, abscess and phlegmon. Therefore, new tools and methods of treatment of complicated forms of caries are proposed, aimed at long-term preservation of teeth as a functional unit of the dental system.
 Objective: to analyze modern laser technologies in the treatment of complicated forms of caries.
 Materials and methods. The study was based on the search and study of original articles on the endodontic treatment of complicated forms of caries using laser radiation in the databases: Russian state library, eLibrary, PubMed, the Cochrane Library, Google Scholar. The main selection of materials was carried out by keywords.
 Results. The literature review describes the positive properties of laser radiation, its mechanism of action, the basics of its use in endodontic treatment, and its application in various branches of dentistry.
 Conclusions. Analyzing the literature data, we can conclude that the use of laser technologies in the treatment of complicated forms of caries is promising. It is possible to achieve high-quality cleaning of the root canal system and the best long-term results. However, the literature does not sufficiently cover the use of Er, Cr:YSGG laser with a wavelength of 2780 nm in the treatment of purulent pulpitis and pulp necrosis. In addition, taking into account the possibility of using lasers at a therapeutic appointment, it is possible to significantly improve the professional level of a dentist, improving the quality of dental care, reducing the number of complications and preventing various dental diseases.