Small, transportable 20 to 30 W TEM oo carbon dioxide lasers offer capability for performance of the largest number of ear, nose, and throat office procedures with a single laser. By combining sharp 200-μm size incision capability with dedicated focused handpieces and layer-by-layer char-free ablation of extended surfaces at low-power levels with the SwiftLase flashscanner technology, such important procedures as laser-assisted uvulapalatoplasty (LAUP), tonsil cryptolysis, lingual tonsillectomy, and other oral cavity procedures can be performed in the office. Treatments normally last a few minutes, using only local anesthesia. With the laser in the superpulse mode and the beam coupled to thin, 1-mm diameter waveguides (FlexiLase, Sharplan Lasers), char-free ablation of deep nasal lesions, such as hypertrophic turbinates, can also be achieved with minimal necrosis. A modified flashscanner technology can also be used in the office for skin resurfacing and hair transplant. Although less versatile and more expensive to buy and to operate, the Nd:YAG laser offers excellent ambulatory treatment of hypertrophic nasal turbinates. Noncontact Nd:YAG fibers can be used endoscopically for the treatment of nasal epistaxis and Nd:YAG contact technology can be used for the ablation of few highly vascular lesions.