Introduction : During his second voyage to the Americas, Christopher Columbus brought to the West Indies, at the end of the 15th century, the sugar cane Saccharum officinarum , originally from Asia. It was only during the 17th century, somewhere around 1640, that an alcohol obtained from the sugar cane or more exactly from molasses, a residue of the sugar cane manufacture, appeared in different islands of the Caribbean. Rum (in French, rhum ) is obtained by distilling fermented cane juice (agricultural rum) or molasses (industrial rum). Today, every year more than 200 000 tons of sugar cane produce 8 M litres of rum and 4000 T of sugar in Martinique. Methods : The authors describe the manufacturing procedure of rum in Martinique (fermentation and distilling processes), then present the various qualities of agricultural and industrial rums and explain the criteria necessary for their A.O.C. appellation. As we know, rum contains 40 to 50% alcohol and is drunk pure or as a cocktail with sugar cane syrup or fruit juices. It may be dangerous for health. So, two pathologies must be considered: those where sugar is concerned and those where alcohol is involved. Some epidemiological studies have been conducted to sum up the situation of Martinique regarding these two problems. Results : In Martinique, type 2 diabetes appearing in the adult is the most frequent form. The prevalence of diabetes is 8 to 10%, which is 2 to 3 times higher than in metropolitan France and the rest of the world. While it is widely recognised that alcoholism has negative health effects, moderate consumption has been found in some research to have a positive effect on longevity. However, in the case of abuse, oxidative and nonoxidative pathways of alcohol metabolism have numerous detrimental consequences that contribute to tissue damage and diseases seen in alcoholic patients. Martinique is in particular exposed to excessive alcohol consumption: 14% of the male population and 2.7% of the female population show an addiction to alcohol. Young people under 18 are two times less likely than young people in metropolitan France to declare that they consume alcohol on a regular basis and four times less likely to declare repetitive drunkenness. As concerns the death rate related to alcoholism, it is considered that 80 to 95% of deaths due to liver cirrhosis, alcoholic psychosis, alcoholism and upper digestive tract cancer are related to an excessive alcohol consumption. On this basis, 85 to 100 deaths can be attributed to alcohol every year in Martinique. In comparison with metropolitan France, Martinique shows a lower death rate for liver cirrhosis and upper digestive tract cancer, but a higher death rate for alcoholic psychosis and alcoholism. This could be due probably to a genetic predisposition of the population. Conclusion : Rum is a strong alcoholic beverage. Its consumption is not forbidden but requires caution, and people may be informed of its adverse health consequences. As for the question: is rum toxic? The answer is: it all depends on how you manage it.