The high level of development is directly proportional to the probability of accidents that may occur. In Indonesia, work accidents in the construction sector still often happened. Based on data from DataIndonesia.id, since 2017-2021 work accidents always increase every year, where in 2017 there were 123,040 accidents and in 2021 it reached 234,270 accidents with an average increase of 18% per year. This study aims to evaluate the implementation of the construction safety management system for toll road infrastructure project refers to the Minister of Public Works and Public Housing Regulation Number 10 of 2021 concerning Guidelines for Construction Safety Management Systems. This research applied a case study method-based with indepth interview and questionnaire techniques which were reviewed by descriptive analysis and statistical tests. The results of this study indicate that the implementation of the construction safety management system on the ABC Toll Road project is in the satisfactory category. There are several indicators whose implementation is not in accordance with the PUPR Ministerial Regulation Number 10 of 2021 due to the lack of insight or knowledge regarding the SMKK implementation program. The formulation of a recommendation strategy for improving the implementation of SMKK can be done by 1) Providing education, training, and/or counseling related to SMKK 2) Compiling SMKK documents in accordance with applicable regulations 3) Strengthening SMKK inspection programs and safety patrols 4) Documenting SMKK implementation activities 5) Procurement of activities such as safety morning talk and Toolbox meeting and procurement of facilities such as K2 information boards 6) Conduct safety meeting with MP regarding construction safety policies and explain to all project stakeholders 7) Provide awards or incentives if construction safety is achieved and 8) Conduct studies more in depth related to SMKK regulations.