Objective To approach the operative effect of dural bilaminar saturation in frontal-temporal skull defect repairs after standard decompressive craniectomy. Methods Fifty-two patients with titanium cranioplasty in frontal -temporal skull defect were retrospectively analyzed;27 of them adopted dural bilaminar saturation in the first standard decompressive craniectomy(test group);25 of them adopted dural monostratal saturation in the first operation(control group). The operation time,blood loss, postoperative complications in the two groups were compared. Results The mean operation time: the test group was(65.00±8.15)min and the control group was(83.00±10.25) min, there was statistically significant differences between the two groups(t=7.059,P 0.05). Conclusion Skull repairs in second standard decompressive craniectomy by dural bilaminar saturation, can be shortened the operation time and lessened amount of bleeding. Key words: Skull defects; Dural bilaminar saturation; Standard decompressive craniectomy