The article represents the results of experimental reproduction of a bone defect (removal of the lower masticatory tooth) of rabbits, followed by closure of the hole by various methods. Experimental animals were divided into 4 groups: 1 group – control, 2 group – suturing «Vikril», 3 group – joining the edges with a laser scalpel and 4 group – welding SOPR in the area of the removed tooth using an electric welding machine «Patonmed» EKVZ-300.After the experimental study, the results of clinical (hyperemia, edema, suture divergence, laser thermometry) and histological parameters were analyzed. The results showed an easier course and reduction of the postoperative period, as well as the formation of a strong weld, which eventually completely restores its structure, using the proposed technique of electric welding of fabrics, in contrast to the classic suture material and laser technology.That is, the above allows us to draw conclusions about the eff ectiveness of the proposed method of connecting the edges of the mucous membrane by electric welding of tissues during cystectomy in the oral cavity. The use of electric welding can reduce the time of surgery by 2 times compared to traditional methods, mainly by reducing the time spent on homeostasis. Also, a large number of methods and technologies for the treatment of odontogenic cysts, on the one hand, indicates a signifi cant development of this area, and on the other hand – the unsatisfactory results of their use. Therefore, further improvement and search for more modern technologies, including methods of approximation of postoperative wounds, in cystectomy operations remains one of the main directions in maxillofacial surgery.